T‐cell‐mediated cytotoxicity against keratinocytes in sulfamethoxazol‐induced skin reaction

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

1968 • 1,363 citations

Molecular Mechanisms of Lymphocyte-Mediated Cytotoxicity and Their Role in Immunological Protection and Pathogenesis In Vivo

1996 • 614 citations

Cutaneous Disease and Drug Reactions in HIV Infection

1993 • 485 citations

Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.

1996 • 401 citations

Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine.

1995 • 351 citations

Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones.

1997 • 279 citations

Drug disposition and drug hypersensitivity

1987 • 199 citations

Adverse Reactions to Trimethoprim-Sulfamethoxazole in Hospitalized Patients

1982 • 186 citations

Erythema multiforme: Clinical, histopathologic, and immunologic study

1984 • 153 citations

Clinical and Laboratory Markers of Hypersensitivity to Trimethoprim-Sulfamethoxazole in Patients with Pneumocystis carinii Pneumonia and AIDS

1993 • 126 citations

T-Cell Subsets in Drug-Induced Toxic Epidermal Necrolysis

1991 • 120 citations

Interferon-gamma concentrations are increased in sera from individuals infected with human immunodeficiency virus type 1.

1989 • 119 citations

Post-Mitotic Human Dermal Fibroblasts Efficiently Support the Growth of Human Follicular Keratinocytes.

1989 • 119 citations

Lymphocyte Activation in Cutaneous Drug Reactions

1995 • 106 citations

Herpes Simplex Virus Protein Targets for CD4 and CD8 Lymphocyte Cytotoxicity in Cultured Epidermal Keratinocytes Treated with Interferon-γ

1996 • 86 citations

Allergic manifestations of human immunodeficiency virus (HIV) infection

1991 • 77 citations

Increased drug reactions in HIV-1-positive patients: a possible explanation based on patterns of immune dysregulation seen in HIV-1 disease. The Military Medical Consortium for the Advancement of Retroviral Research (MMCARR).

1997 • 61 citations

Increased drug reactions in HIV-1-positive patients: a possible explanation based on patterns of immune dysregulation seen in HIV-1 disease^*

1997 • 47 citations

Immunohistological assessment of cutaneous drug hypersensitivity in patients with HIV infection

1994 • 43 citations

Interleukin-12 expression in human lymphomas and nonneoplastic lymphoid disorders

1995 • 40 citations

Successful prophylaxis of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in AIDS patients with previous allergic reactions.

1989 • 30 citations

Successful prophylaxis of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in AIDS patients with previous allergic reactions.

1989 • 17 citations

Managing HIV. Part 3: Mechanisms of disease. 3.5 How HIV leads to hypersensitivity reactions.

1996 • 10 citations

Lytic susceptibility of target cells to cytotoxic T cells is determined by their constitutive major histocompatibility complex class I antigen expression and cytokine-induced activation status.

1994 • 9 citations

3.5 How HIV leads to hypersensitivity reactions

1996 • 8 citations