Interaction of enrofloxacin with breast cancer resistance protein (BCRP/ABCG2): influence of flavonoids and role in milk secretion in sheep

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

2012 • 1,196 citations

Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

2001 • 1,116 citations

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes.

1999 • 810 citations

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

2002 • 682 citations

Role of Breast Cancer Resistance Protein in the Bioavailability and Fetal Penetration of Topotecan

2000 • 640 citations

The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

2000 • 528 citations

Impact of Drug Transporter Studies on Drug Discovery and Development

2003 • 493 citations

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk

2005 • 412 citations

Identification of a missense mutation in the bovine ABCG2 gene with a major effect on the QTL on chromosome 6 affecting milk yield and composition in Holstein cattle

2005 • 359 citations

Effects of the Flavonoids Biochanin A, Morin, Phloretin, and Silymarin on P-Glycoprotein-Mediated Transport

2002 • 314 citations

Functional Characterization of the Human Multidrug Transporter, ABCG2, Expressed in Insect Cells

2001 • 310 citations

Phytoestrogens/Flavonoids Reverse Breast Cancer Resistance Protein/ABCG2-Mediated Multidrug Resistance

2004 • 280 citations

Human Breast Cancer Resistance Protein: Interactions with Steroid Drugs, Hormones, the Dietary Carcinogen 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and Transport of Cimetidine

2004 • 278 citations

Interaction of the breast cancer resistance protein with plant polyphenols

2004 • 222 citations

The Breast Cancer Resistance Protein (BCRP/ABCG2) Affects Pharmacokinetics, Hepatobiliary Excretion, and Milk Secretion of the Antibiotic Nitrofurantoin

2005 • 220 citations

BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION

2006 • 196 citations

Desirable characteristics of forage legumes for improving protein utilization in ruminants.

1995 • 188 citations

The Product of the ABC Half-Transporter Gene ABCG2 (BCRP/MXR/ABCP) Is Expressed in the Plasma Membrane

2000 • 184 citations

Sterol Transport by the Human Breast Cancer Resistance Protein (ABCG2) Expressed in Lactococcus lactis

2003 • 158 citations

Simple, rapid determination of enrofloxacin and ciprofloxacin in bovine milk and plasma by high-performance liquid chromatography with fluorescence detection

2004 • 155 citations

Pharmacokinetics of enrofloxacin after single intravenous, intramuscular and subcutaneous injections in lactating cows

1995 • 150 citations

Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin

2003 • 144 citations

Combined Effects of Multiple Flavonoids on Breast Cancer Resistance Protein (ABCG2)-Mediated Transport

2004 • 138 citations

Multiresidue determination of fluoroquinolones in milk by column liquid chromatography with fluorescence and ultraviolet absorbance detection

2004 • 131 citations

TRANSPORT OF ANTHELMINTIC BENZIMIDAZOLE DRUGS BY BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2)

2005 • 122 citations

N-Linked Glycosylation of the Human ABC Transporter ABCG2 on Asparagine 596 Is Not Essential for Expression, Transport Activity, or Trafficking to the Plasma Membrane

2005 • 110 citations

Pharmacokinetics of Enrofloxacin and Danofloxacin in Plasma, Inflammatory Exudate, and Bronchial Secretions of Calves following Subcutaneous Administration

1999 • 108 citations

Intestinal Secretion Is a Major Route for Parent Ivermectin Elimination in the Rat

2002 • 104 citations

Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway?

1994 • 94 citations

Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice.

2004 • 83 citations

Selamectin is a potent substrate and inhibitor of human and canine P‐glycoprotein

2005 • 77 citations

Transport of pefloxacin across the bacterial cytoplasmic membrane in quinolone-susceptible Staphylococcus aureus

1992 • 77 citations

Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and intramuscular administrations in sheep

1996 • 73 citations

Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry

2003 • 70 citations

Comparative pharmacokinetics of enrofloxacin in mice, rats, rabbits, sheep, and cows

1999 • 66 citations

Intestinal elimination of albendazole sulfoxide: pharmacokinetic effects of inhibitors

2003 • 53 citations

Benzimidazoles, potent anti-mitotic drugs: Substrates for the P-glycoprotein transporter in multidrug-resistant cells

1994 • 52 citations

Antibiotics and Breast-Feeding

2002 • 45 citations

Interactions between cimetidine, nitrofurantoin, and probenecid active transport into rat milk.

2001 • 45 citations

Intestinal elimination of ofloxacin enantiomers in the rat: evidence of a carrier-mediated process

1996 • 42 citations

Pharmacokinetics of enrofloxacin in lactating sheep

2003 • 42 citations

Influence of albendazole on the disposition kinetics and milk antimicrobial equivalent activity of enrofloxacin in lactating goats

2003 • 30 citations

Penetration of enrofloxacin and ciprofloxacin into breast milk, and pharmacokinetics of the drugs in lactating rabbits and neonatal offspring

1996 • 26 citations