Transport of pefloxacin across the bacterial cytoplasmic membrane in quinolone-susceptible Staphylococcus aureus

Lipid Asymmetry in Membranes

1979 • 1,245 citations

Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli.

1980 • 584 citations

Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones

1990 • 479 citations

Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug-DNA binding model

1989 • 417 citations

Aqueous solubilities of some variously substituted quinolone antimicrobials

1990 • 284 citations

Mechanisms of Active Transport in Isolated Membrane Vesicles

1971 • 201 citations

Endogenous active efflux of norfloxacin in susceptible Escherichia coli

1988 • 183 citations

Mechanisms of quinolone resistance in Escherichia coli: characterization of nfxB and cfxB, two mutant resistance loci decreasing norfloxacin accumulation

1989 • 129 citations

Investigations into the mechanism of action of the antibacterial agent norfloxacin

1984 • 126 citations

Uptake of ciprofloxacin by macrophages.

1985 • 102 citations

Coupling between energy conservation and active transport of serine in Escherichia coli

1973 • 70 citations

Fluorometric measurement of ofloxacin uptake by human polymorphonuclear leukocytes

1989 • 70 citations

Factors influencing the accumulation of ciprofloxacin in Pseudomonas aeruginosa

1989 • 61 citations

Accumulation of enoxacin by Escherichia coli and Bacillus subtilis

1987 • 60 citations

Interaction of the fluoroquinolone antimicrobial agents ciprofloxacin and enoxacin with liposomes

1989 • 46 citations

Inhibition by quinolones of DNA gyrase from Staphylococcus aureus

1991 • 44 citations

Quinolone accumulation in Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus

1992 • 43 citations

Quinolone antimicrobial agents: mechanism of action and resistance development.

1989 • 41 citations

DNA gyrase of Staphylococcus aureus and inhibitory effect of quinolones on its activity

1988 • 40 citations

In vitro evaluation of WIN 57273, a new broad-spectrum fluoroquinolone

1990 • 32 citations

Contribution of permeability and sensitivity to inhibition of DNA synthesis in determining susceptibilities of Escherichia coli, Pseudomonas aeruginosa, and Alcaligenes faecalis to ciprofloxacin

1989 • 23 citations

Resistance emerging after pefloxacin therapy of experimental Enterobacter cloacae peritonitis

1989 • 18 citations