Alteration of Signal-Transducing Molecules and Phenotypical Characteristics in Peripheral Blood Lymphocytes from Gastric Carcinoma Patients

The B7 and CD28 receptor families

1994 • 1,342 citations

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1992 • 1,046 citations

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

CD28- T lymphocytes. Antigenic and functional properties.

1993 • 403 citations

Anergic T Cells as Suppressor Cells in Vitro

1994 • 389 citations

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma.

1993 • 385 citations

Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

1993 • 344 citations

Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma.

1996 • 216 citations

Alterations in T cell receptor and signal transduction molecules in melanoma patients.

1995 • 192 citations

Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex.

1995 • 150 citations

Variable expression of CD3‐ζ chain in tumor‐infiltrating lymphocytes (TIL) derived from renal‐cell carcinoma: Relationship with til phenotype and function

1995 • 111 citations

Tumor specific cytolysis by tumor infiltrating lymphocytes in breast cancer

1994 • 109 citations

p56lck association with CD4 is required for the interaction between CD4 and the TCR/CD3 complex and for optimal antigen stimulation.

1992 • 94 citations

Tumor-infiltrating lymphocytes: their phenotype, functions and clinical use

1994 • 92 citations

Abnormal signal transduction by T cells of mice with parental tumors is not seen in mice bearing IL-2-secreting tumors.

1994 • 82 citations

Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis.

1997 • 81 citations

T cells infiltrating non-Hodgkin's B cell lymphomas show altered tyrosine phosphorylation pattern even though T cell receptor/CD3-associated kinases are present.

1995 • 76 citations

T cells from late tumor-bearing mice express normal levels of p56lck, p59fyn, ZAP-70, and CD3 zeta despite suppressed cytolytic activity.

1995 • 57 citations

The role of CD4+ tumor-infiltrating lymphocytes in human solid tumors

1995 • 57 citations

T cell immune response to cancer in humans and its relevance for immunodiagnosis and therapy.

1992 • 43 citations

Low T cell reactivity to combined CD3 plus CD28 stimulation is predictive for progression to AIDS: correlation with decreased CD28 expression

1996 • 36 citations

Down‐regulation of CD28 via Fas (CD95): influence of CD28 on T‐cell apoptosis

1998 • 31 citations

Alteration of signal-transducing molecules in tumor-infiltrating lymphocytes and peripheral blood T lymphocytes from human colorectal carcinoma patients

1998 • 30 citations

Immunoregulatory effects of CD4+ T helper subsets in human melanoma

1995 • 27 citations

Novel immunologic strategies in ovarian carcinoma

1992 • 22 citations