Sequences in the rev‐responsive element responible for premature translational arrest in the human‐immunodeficiency‐virus‐type‐1 envelope

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

Nucleotide sequence of the AIDS virus, LAV

1985 • 1,225 citations

ALTERNATIVE SPLICING IN THE CONTROL OF GENE EXPRESSION

1989 • 701 citations

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.

1989 • 634 citations

Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

1988 • 608 citations

Genetic variability of the AIDS virus: Nucleotide sequence analysis of two isolates from African patients

1986 • 513 citations

HIV-1 structural gene expression requires binding of the rev trans-activator to its RNA target sequence

1990 • 457 citations

Errors and alternatives in reading the universal genetic code

1989 • 407 citations

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

1989 • 400 citations

Regulation of human immunodeficiency virus env expression by the rev gene product

1989 • 365 citations

HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev response element region

1990 • 354 citations

Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein

1991 • 333 citations

Development of a sensitive quantitative focal assay for human immunodeficiency virus infectivity

1988 • 314 citations

Translational frameshifting generates the gamma subunit of DNA polymerase III holoenzyme.

1990 • 300 citations

The Molecular Biology of Human Immunodeficiency Virus Type 1 Infection

1991 • 278 citations

Retrovirus Envelope Glycoproteins

1990 • 276 citations

Induction of HTLV-III/LAV from a Nonvirus-Producing T-Cell Line: Implications for Latency

1986 • 264 citations

Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs

1990 • 250 citations

Programmed ribosomal frameshifting generates theEscherichia coliDNA polymerase III γ subunit from within the τ subunit reading frame

1990 • 243 citations

Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu 2 RNAs.

1991 • 232 citations

Ribosome gymnastics—Degree of difficulty 9.5, style 10.0

1990 • 226 citations

The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs.

1992 • 208 citations

Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex.

1990 • 190 citations

Generation of human monoclonal antibodies to human immunodeficiency virus.

1989 • 183 citations

Mutational analysis of the cleavage sequence of the human immunodeficiency virus type 1 envelope glycoprotein precursor gp160

1989 • 172 citations

Identification and characterization of intragenic sequences which repress human immunodeficiency virus structural gene expression

1991 • 160 citations

CUG initiation codon used for the synthesis of a cell surface antigen coded by the murine leukemia virus

1989 • 152 citations

Functional Analysis of CAR, the Target Sequence for the Rev Protein of HIV-1

1989 • 152 citations

Hepatitis B surface antigen: an unusual secreted protein initially synthesized as a transmembrane polypeptide.

1986 • 142 citations

Mutational analysis of the human immunodeficiency virus type 1 env gene product proteolytic cleavage site

1990 • 131 citations

Castanospermine inhibits alpha-glucosidase activities and alters glycogen distribution in animals.

1985 • 130 citations

Analysis of rev gene function on human immunodeficiency virus type 1 replication in lymphoid cells by using a quantitative polymerase chain reaction method

1989 • 122 citations

Minimal Rev-response element for type 1 human immunodeficiency virus

1991 • 117 citations

Multiple topogenic sequences in bovine opsin.

1987 • 115 citations

Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport

1989 • 103 citations

Transcriptional and post-transcriptional regulation of TcR, CD4 and CD8 gene expression during activation of normal human T lymphocytes.

1990 • 88 citations

Stop making sense or Regulation at the level of termination in eukaryotic protein synthesis

1988 • 78 citations

Mutations within the human immunodeficiency virus type 1 gp160 envelope glycoprotein alter its intracellular transport and processing

1991 • 75 citations

The role of cytosolic and membrane factors in processing of the human beta-2 adrenergic receptor following translocation and glycosylation in a cell-free system.

1990 • 55 citations

Sequences in the U5-gag-pol region influence early and late pathogenic effects of Friend and Moloney murine leukemia viruses

1990 • 23 citations

Functional tolerance of the human immunodeficiency virus type 1 envelope signal peptide to mutations in the amino-terminal and hydrophobic regions

1992 • 19 citations

In vitro synthesis and processing of herpes simplex virus type 2 gG-2, using cell-free transcription and translation systems

1990 • 12 citations