Generation of human monoclonal antibodies to human immunodeficiency virus.

Abnormalities of B-Cell Activation and Immunoregulation in Patients with the Acquired Immunodeficiency Syndrome

1983 • 1,625 citations

Defective Regulation of Epstein–Barr Virus Infection in Patients with Acquired Immunodeficiency Syndrome (AIDS) or AIDS-Related Disorders

1986 • 384 citations

HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN TWO COHORTS OF HOMOSEXUAL MEN: NEUTRALISING SERA AND ASSOCIATION OF ANTI-GAG ANTIBODY WITH PROGNOSIS

1987 • 249 citations

Mechanisms of B cell activation in patients with acquired immunodeficiency syndrome and related disorders. Contribution of antibody-producing B cells, of Epstein-Barr virus-infected B cells, and of immunoglobulin production induced by human T cell lymphotropic virus, type III/lymphadenopathy-associated virus.

1986 • 229 citations

Human monoclonal antibody production

1987 • 224 citations

Restricted neutralization of divergent human T-lymphotropic virus type III isolates by antibodies to the major envelope glycoprotein.

1986 • 204 citations

Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24

1988 • 203 citations

Characterization of a Circulating Subpopulation of Spontaneous Antitetanus Toxoid Antibody Producing B Cells Following in Vivo Booster Immunization

1979 • 201 citations

Streptococcus pneumoniae infections and bacteremia in patients with acquired immune deficiency syndrome, with report of a pneumococcal vaccine failure.

1984 • 180 citations

Construction and testing of mouse--human heteromyelomas for human monoclonal antibody production.

1983 • 168 citations

Generation of human monoclonal antibodies reactive with cellular antigens.

1983 • 164 citations

Sera from HTLV-III/LAV antibody-positive individuals mediate antibody-dependent cellular cytotoxicity against HTLV-III/LAV-infected T cells.

1987 • 154 citations

Defective B-Lymphocyte Function in Homosexual Men in Relation to the Acquired Immunodeficiency Syndrome

1984 • 146 citations

In vitro antigen-induced, antigen-specific antibody production in man. Specific and polyclonal components, kinetics, and cellular requirements.

1981 • 130 citations

Detection of cell surface and intracellular antigens by human monoclonal antibodies. Hybrid cell lines derived from lymphocytes of patients with malignant melanoma.

1983 • 110 citations

The high efficiency, human B cell immortalizing heteromyeloma CB-F7

1988 • 101 citations

B-cell activation in HIV infection: relationship of spontaneous immunoglobulin secretion to various immunological parameters.

1988 • 84 citations

Spontaneous in vitro production of virus-specific antibody by lymphocytes from HIV-infected subjects

1988 • 82 citations

Immunoglobulin expression by human B lymphocytes clonally transformed by Epstein Barr virus.

1982 • 78 citations

Nonrandom development of immunologic abnormalities after infection with human immunodeficiency virus: implications for immunologic classification of the disease.

1987 • 77 citations

Human lymphocyte Hybridomas and Monoclonal Antibodies

1986 • 74 citations

Serum IgD elevation is an early marker of B cell activation during infection with the human immunodeficiency viruses.

1987 • 60 citations

Senescence of a human lymphoblastoid clone producing anti‐Rhesus(D)

1985 • 55 citations

Characterization and epitope mapping of a human monoclonal antibody reactive with the envelope glycoprotein of human immunodeficiency virus.

1987 • 51 citations

Human Hybridomas and Monoclonal Antibodies

1985 • 48 citations

A monoclonal antibody against LAV gag precursor: use for viral protein analysis and antigenic expression in infected cells.

1986 • 33 citations

Human monoclonal antibody directed against gag gene products of the human immunodeficiency virus.

1988 • 30 citations

Antibody to a synthetic peptide detects a conserved region of retrovirus transmembrane proteins

1985 • 22 citations

Idiotypic Network in Myasthenia Gravis Demonstrated by Human Monoclonal B‐Cell Lines

1987 • 20 citations

A sensitive radioimmunoprecipitation assay for human immunodeficiency virus (HIV)

1988 • 17 citations

High Frequency of Loss of Human Kappa Light Chain Expression in Mouse-Human Heterohybridomas

1987 • 12 citations

Transcription and replication of human immunodeficiency virus-1 in B lymphocytes in vitro.

1988 • 12 citations

Potential use of serotherapy in the prevention and treatment of infection with the human immunodeficiency virus

1987 • 10 citations

Epitope mapping of human immunodeficiency virus: a monoclonal approach.

1987 • 5 citations