The Role of Copper Reduction by α-Tocopherol in Low-Density Lipoprotein Oxidation

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Role of oxidized low density lipoprotein in atherogenesis.

1991 • 2,691 citations

The role of lipid peroxidation and antioxidants in oxidative modification of LDL

1992 • 2,335 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

1984 • 1,631 citations

[8] Reassessment of Ellman's reagent

1983 • 1,076 citations

Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein

1993 • 710 citations

Measurement of Plasma Hydroperoxide Concentrations by the Ferrous Oxidation-Xylenol Orange Assay in Conjunction with Triphenylphosphine

1994 • 657 citations

Role of vitamin E in preventing the oxidation of low-density lipoprotein

1991 • 649 citations

Role of oxidatively modified LDL in atherosclerosis

1990 • 614 citations

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture.

1984 • 547 citations

Monocytes and Neutrophils Oxidize Low Density Lipoprotein Making It Cytotoxic

1985 • 536 citations

Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant

1992 • 513 citations

Effect of oral supplementation with D-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation.

1991 • 477 citations

The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells.

1987 • 465 citations

Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions

1992 • 463 citations

Effect of dietary antioxidant combinations in humans. Protection of LDL by vitamin E but not by beta-carotene.

1993 • 408 citations

α-tocopherol consumption during low-density-lipoprotein oxidation

1990 • 312 citations

Effect of dietary supplementation with alpha-tocopherol on the oxidative modification of low density lipoprotein.

1992 • 299 citations

Mechanisms of copper- and iron-dependent oxidative modification of human low density lipoprotein

1993 • 282 citations

Intact human ceruloplasmin oxidatively modifies low density lipoprotein.

1994 • 265 citations

Requirement for, Promotion, or Inhibition by α-Tocopherol of Radical-Induced Initiation of Plasma Lipoprotein Lipid Peroxidation

1997 • 264 citations

Long-lived reactive species on free-radical-damaged proteins

1992 • 224 citations

Effects of native and oxidized low density lipoproteins on formation and inactivation of endothelium-derived relaxing factor.

1991 • 190 citations

Oxidation of low-density lipoproteins: intraindividual variability and the effect of dietary linoleate supplementation

1993 • 179 citations

Lipid hydroperoxide involvement in copper-dependent and independent oxidation of low density lipoproteins.

1991 • 177 citations

The oxidative modification of low-density lipoproteins by macrophages

1990 • 169 citations

Cellular oxidation of low density lipoprotein is caused by thiol production in media containing transition metal ions

1993 • 159 citations

Lipoprotein oxidation: mechanistic aspects, methodological approaches and clinical relevance.

1994 • 154 citations

Reduction of Copper, but Not Iron, by Human Low Density Lipoprotein (LDL)

1995 • 152 citations

Role of lipoprotein-copper complex in copper catalyzed-peroxidation of low-density lipoprotein

1992 • 145 citations

Varying susceptibility of different low density lipoproteins to oxidative modification.

1991 • 140 citations

Vitamin E content and low density lipoprotein oxidizability induced by free radicals

1990 • 137 citations

Lipoprotein oxidation

1994 • 122 citations

α-Tocopherol as a Reductant for Cu(II) in Human Lipoproteins

1996 • 117 citations

Mechanistic and genetic aspects of susceptibility of LDL to oxidation

1993 • 115 citations

Oxidation of low-density lipoproteins: questions of initiation, propagation, and the effect of antioxidants

1995 • 113 citations

Oxidation resistance, oxidation rate, and extent of oxidation of human low-density lipoprotein depend on the ration of oleic acid content to linoleic acid content studies in vitamin E deficient subjects

1993 • 104 citations

Interaction of α-tocopherol with copper and its effect on lipid peroxidation

1994 • 94 citations

Prooxidant role of vitamin E in copper induced lipid peroxidation

1993 • 93 citations

Role of leukotrienes in leukocyte adhesion following systemic administration of oxidatively modified human low density lipoprotein in hamsters.

1991 • 81 citations

The oxidative modification of low density lipoprotein by human lymphocytes

1992 • 74 citations

The role of oxidized low-density lipoprotein in atherogenesis

1993 • 73 citations

Low density lipoprotein composition and oxidizability in coronary disease — apparent favourable effect of beta blockers

1992 • 61 citations

Oxidation of low-density lipoproteins: effect of antioxidant content, fatty acid composition and intrinsic phospholipase activity on susceptibility to metal ion-induced oxidation

1995 • 55 citations

Predisposition to LDL oxidation during copper-catalyzed oxidative modification and its relation to α-tocopherol content in humans

1991 • 48 citations

The effect of lipoproteins on the release of some eicosanoids by stimulated human leukocytes. A possible role in atherogenesis.

1991 • 24 citations