Molecular anatomy of the neuro-immune connection

The American Journal of Physiology

1899 • 5,863 citations

Noradrenergic and peptidergic innervation of lymphoid tissue

1985 • 996 citations

Effect of Neuropeptides on Production of Inflammatory Cytokines by Human Monocytes

1988 • 929 citations

The Immune-Hypothalamic-Pituitary-Adrenal Axis*

1989 • 671 citations

Stress and immunity: An integrated view of relationships between the brain and the immune system

1989 • 533 citations

Opioid Peptides and Opioid Receptors in Cells of the Immune System

1988 • 436 citations

Reduction of immune function in life stress and depression

1990 • 345 citations

Neuroimmune networks: physiology and diseases

1990 • 228 citations

Brain, behavior, and immunity

1987 • 199 citations

NPY-, galanin-, VIP/PHI-, CGRP- and substance P-immunoreactive neuronal subpopulations in cat autonomic and sensory ganglia and their projections

1989 • 193 citations

Neuroendocrine, Sympathetic and Metabolic Responses Induced by Interleukin-1

1989 • 164 citations

Multiple neuropeptides in nerves supplying mammalian lymph nodes: messenger candidates for sensory and autonomic neuroimmunomodulation?

1988 • 147 citations

Selective localization of vasoactive intestinal peptide and substance P in human eosinophils

1987 • 145 citations

Neuropeptide Innervation of Lymphoid Organsa

1990 • 143 citations

Receptors for sensory neuropeptides in human inflammatory diseases: Implications for the effector role of sensory neurons

1989 • 138 citations

Innervation of the spleen in the rat: Evidence for absence of afferent innervation

1989 • 138 citations

Neuropeptide Y, enkephalin and noradrenaline coexist in sympathetic neurons innervating the bovine spleen

1986 • 119 citations

Psychoneuroimmunology for the psychoneuroendocrinologist: A review of animal studies of nervous system-immune system interactions

1989 • 118 citations

Neuropeptides as growth factors. Possible roles in human diseases

1989 • 110 citations

Peptide neuroanatomy of adjuvant-induced arthritic inflammation in rat

1988 • 102 citations

The localization of sensory nerve fibers and receptor binding sites for sensory neuropeptides in canine mesenteric lymph nodes

1988 • 99 citations

Target-related patterns of co-existence of neuropeptide Y, vasoactive intestinal peptide, enkephalin and substance P in cranial parasympathetic neurons innervating the facial skin and exocrine glands of guinea-pigs

1990 • 96 citations

Brain modulation of the immune system: association between lymphocyte responsiveness and paw preference in mice

1988 • 93 citations

Vasoactive intestinal peptide and related peptides.

1988 • 93 citations

Norepinephrine and serotonin content of the murine spleen: Its relationship to lymphocyte β-adrenergic receptor density and the humoral immune response in vivo and in vitro

1988 • 92 citations

Neuropeptides : basics and perspectives

1990 • 87 citations

Tachykinins, calcitonin gene-related peptide and neuropeptide Y in nerves of the mammalian thymus: interactions with mast cells in autonomic and sensory neuroimmunomodulation?

1989 • 87 citations

Interferon‐gamma‐like immunoreactivity in certain neurons of the central and peripheral nervous system

1989 • 83 citations

Substance P induces chemotaxis of neutrophils in normal and capsaicin‐treated rats

1987 • 72 citations

Neuroimmunomodulation: facts and dilemmas

1989 • 71 citations

Prejunctional modulatory action of neuropeptide Y on peripheral terminals of capsaicin‐sensitive sensory nerves

1989 • 70 citations

Peripheral effects of opioid drugs on capsaicin-sensitive neurones of the guinea-pig bronchus and rabbit ear

1987 • 67 citations

Bidirectional Communication between the Neuroendocrine and Immune Systems Common Hormones and Hormone Receptors

1990 • 63 citations

Neuropeptide y- and alpha-adrenergic receptors in pig spleen: Localization, binding characteristics, cyclic amp effects and functional responses in control and denervated animals

1988 • 63 citations

Neuropeptides and immunopeptides: Messengers in a neuroimmune axis

1989 • 60 citations

Substance P, Cytokines, and Arthritis

1990 • 59 citations

Parallel development of noradrenergic innervation and cellular compartmentation in the rat spleen

1989 • 59 citations

Multiple peptides in cutaneous nerves: regulators under physiological conditions and a pathogenetic role in skin disease?

1988 • 56 citations

The neuroimmune link in the bronchus-associated lymphoid tissue (BALT) of cat and rat: Peptides and neural markers

1991 • 55 citations

Conditioned medium from activated splenocytes increases substance P in sympathetic ganglia

1990 • 52 citations

The neuro-B cell link of peptidergic innervation in the Bursa Fabricii

1991 • 51 citations

The Tachykinin Neuroimmune Connection in Inflammatory Pain

1991 • 50 citations

Interrelation of peptidergic innervation with mast cells and ED1-positive cells in rat thymus

1991 • 48 citations

Gamma interferon-like immunoreactivity in the rat nervous system

1990 • 47 citations

Substance P-immunoreactive nerve fibers in tracheobronchial lymph nodes of the guinea pig: Origin, ultrastructure and coexistence with other peptides

1990 • 45 citations

Depression of lymphocyte traffic in sheep by vasoactive intestinal peptide (VIP).

1988 • 44 citations

Muscarinic cholinergic binding sites on rat lymphocytes

1988 • 42 citations

Mushroom allergy

1988 • 41 citations

Opioid Peptides.

1990 • 37 citations

Tachykinins and Calcitonin Gene-Related Peptide in Oxazolone-Induced Allergic Contact Dermatitis in Mice

1990 • 36 citations

Substance P receptors in rat spleen: characterization and autoradiographic distribution

1986 • 34 citations

Interleukin‐1 Interaction with neuroregulatory systems: Selective enhancement by recombinant human and mouse interleukin‐1 of in vitro opioid peptide receptor binding in rat brain

1989 • 33 citations

Production of Neuroendocrine Peptide Hormones by the Immune System

1988 • 33 citations

The neuroimmune connection in human tonsils

1991 • 32 citations

Capsaicin-sensitive tachykinin-like immunoreactivity in the thymus of rats and guinea-pigs

1988 • 31 citations

Effect of the neuropeptides β‐MSH, neurotensin, NPY, PHI, somatostatin and substance P on proliferation of lymphocytes in vitro

1989 • 28 citations

Inhibition of Natural Killer Activity by Calcitonin Gene-Related Peptide

1989 • 27 citations

Peptidergic Innervation in Chronic Pancreatitis

1990 • 23 citations

Immunoregulation by neuroendocrine factors

1989 • 23 citations

The Cholinergic and Adrenergic Innervation of the Rat Thymus

1988 • 21 citations

A Decade of neuropeptides : past, present, and future

1990 • 20 citations

Thymic lymphopoiesis and cholinergic innervation.

1988 • 20 citations

Neuropeptides and the Immune System: Substance P Receptors in Bronchus‐Associated Lymphoid Tissue of Rat

1987 • 20 citations

Increased Delayed-Type Hypersensitivity Reaction in Rats Neuromanipulated with Capsaicin

1989 • 18 citations

Distribution of Met-enkephalyl-Arg-Gly-Leu in rat larynx: Partial coexistence with vasoactive intestinal polypeptide, peptide histidine isoleucine and neuropeptide Y

1990 • 15 citations

Neuropeptides as Neuronal Growth Regulating Factors

1990 • 11 citations

[Immunohistochemical demonstration of neuropeptide Y in the normal human thymus and in thymoma].

1989 • 2 citations