High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT _3AB receptor

Single-Channel Recording

1995 • 2,565 citations

Molecular, pharmacological and functional diversity of 5-HT receptors

2002 • 1,822 citations

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

2001 • 1,736 citations

The spectrum of behaviors influenced by serotonin

1998 • 1,126 citations

Fast events in single‐channel currents activated by acetylcholine and its analogues at the frog muscle end‐plate.

1985 • 768 citations

Molecular Structure and Function of the Glycine Receptor Chloride Channel

2004 • 744 citations

The 5-HT3B subunit is a major determinant of serotonin-receptor function

1999 • 555 citations

Nervous system distribution of the serotonin 5-HT3 receptor mRNA.

1993 • 369 citations

Fitting and Statistical Analysis of Single-Channel Records

1995 • 333 citations

Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E

2003 • 245 citations

Autosomal dominant nocturnal frontal lobe epilepsy

2004 • 237 citations

The 5-HT₃receptor as a therapeutic target

2007 • 228 citations

5-hydroxytryptamine is a fast excitatory transmitter at 5-HT3 receptors in rat amygdala

1992 • 192 citations

The molecular basis of the structure and function of the 5-HT 3 receptor: a model ligand-gated ion channel (Review)

2002 • 188 citations

Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species.

1995 • 179 citations

Variations in the 5-Hydroxytryptamine Type 3B Receptor Gene as Predictors of the Efficacy of Antiemetic Treatment in Cancer Patients

2003 • 157 citations

Effects of the Serotonin Type 2A, 3A and 3B Receptor and the Serotonin Transporter Genes on Paroxetine and Fluvoxamine Efficacy and Adverse Drug Reactions in Depressed Japanese Patients

2006 • 155 citations

Characterization of the Novel Human Serotonin Receptor Subunits 5-HT_3C,5-HT_3D, and 5-HT_3E

2007 • 145 citations

The Cheng-Prusoff relationship: something lost in the translation

1993 • 131 citations

Association between the 5′ UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder

2001 • 129 citations

Physiology and pathophysiology of the 5-HT3 receptor.

2004 • 107 citations

Atomic force microscopy reveals the stoichiometry and subunit arrangement of 5-HT₃receptors

2005 • 107 citations

Chronic Fluoxetine Treatment Increases the Expression of PSA-NCAM in the Medial Prefrontal Cortex

2006 • 95 citations

Distinguishable Haplotype Blocks in the HTR3A and HTR3B Region in the Japanese Reveal Evidence of Association of HTR3B with Female Major Depression

2006 • 87 citations

Calcium influx through presynaptic 5-HT3 receptors facilitates GABA release in the hippocampus: in vitro slice and synaptosome studies

2004 • 84 citations

Polymorphisms in the 5-Hydroxytryptamine 2A Receptor and CytochromeP4502D6 Genes Synergistically Predict Fluvoxamine-Induced Side Effects in Japanese Depressed Patients

2005 • 74 citations

Modulation of Dopamine Transmission by 5HT2C and 5HT3 Receptors: A Role in the Antidepressant Response

2006 • 72 citations

The effect of 5-hydroxytryptamine 3A and 3B receptor genes on nausea induced by paroxetine

2006 • 71 citations

Physiology and pathophysiology of the 5‐HT₃receptor

2004 • 68 citations

Evidence for a vagal pathophysiology for bulimia nervosa and the accompanying depressive symptoms

2006 • 56 citations

Activation of presynaptic 5-HT3 receptors facilitates glutamatergic synaptic inputs to area postrema neurons in rat brain slices

2004 • 54 citations

The 5-HT 3 receptor as a therapeutic target

2007 • 48 citations

Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression

2007 • 44 citations

Identification of 5-HT3A and 5-HT3B receptor subunits in human hippocampus

2007 • 34 citations

Immunolabelling of the 5‐HT_3B receptor subunit in the central and peripheral nervous systems in rodents

2007 • 26 citations

Potentiation of 5-HT3 receptor functions in the hippocampal CA1 region of rats following repeated electroconvulsive shock treatments

2001 • 26 citations

Rapid and Direct Modulation of GABAAReceptors by Halothane

2000 • 21 citations