Variations in the 5-Hydroxytryptamine Type 3B Receptor Gene as Predictors of the Efficacy of Antiemetic Treatment in Cancer Patients

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

1997 • 995 citations

Primary Structure And Functional Expression of the 5HT ₃ Receptor, A Serotonin-gated Ion Channel

1991 • 976 citations

Molecular biology of 5-HT receptors

1994 • 679 citations

Recommendations for the Use of Antiemetics: Evidence-Based, Clinical Practice Guidelines

1999 • 678 citations

Proposal for classifying the acute emetogenicity of cancer chemotherapy.

1997 • 619 citations

The 5-HT3B subunit is a major determinant of serotonin-receptor function

1999 • 555 citations

The Area Postrema and Vomiting

1994 • 337 citations

The Pharmacological and Functional Characteristics of the Serotonin 5-HT3A Receptor Are Specifically Modified by a 5-HT3B Receptor Subunit

1999 • 278 citations

5-HT3 Receptor Antagonists for the Prevention of Chemotherapy-Induced Nausea and Vomiting

1998 • 268 citations

Patient-Tailored Antiemetic Treatment With 5-Hydroxytryptamine Type 3 Receptor Antagonists According to Cytochrome P-450 2D6 Genotypes

2002 • 254 citations

PREVENTION OF EMESIS IN PATIENTS RECEIVING CYTOTOXIC DRUGS BY GR38032F, A SELECTIVE 5-HT3 RECEPTOR ANTAGONIST

1987 • 193 citations

The 5-HT3 Receptor Channel

1995 • 180 citations

Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species.

1995 • 179 citations

Defining the Emetogenicity of Cancer Chemotherapy Regimens: Relevance to Clinical Practice

1999 • 145 citations

Ultrastructure of the 5‐Hydroxytryptamine₃ Receptor

1995 • 132 citations

Cloning and functional expression of a human 5-hydroxytryptamine type 3AS receptor subunit.

1995 • 117 citations

Double-blind, dose-finding study of four intravenous doses of dexamethasone in the prevention of cisplatin-induced acute emesis. Italian Group for Antiemetic Research.

1998 • 95 citations

Mechanism of the Anti-Emetic Activity of 5-HT<sub>3</sub> Receptor Antagonists

1992 • 90 citations

An overview of randomised studies comparing 5-HT3 receptor antagonists to conventional anti-emetics in the prophylaxis of acute chemotherapy-induced vomiting

1997 • 83 citations

Desperately seeking subunits: are native 5-HT3 receptors really homomeric complexes?

1998 • 65 citations

Cancer therapy, vomiting, and antiemetics

1990 • 61 citations

Modified 5-HT3A receptor function by co-expression of alternatively spliced human 5-HT3A receptor isoforms

2000 • 60 citations

The Effectiveness of a Single Intravenous Dose of Ondansetron

1992 • 20 citations

Molecular Cloning of Alternatively Spliced Human 5‐HT₃ Receptor cDNAs^a

1998 • 17 citations

Deleted Work

1955 • 0 citations