Effects of the Serotonin Type 2A, 3A and 3B Receptor and the Serotonin Transporter Genes on Paroxetine and Fluvoxamine Efficacy and Adverse Drug Reactions in Depressed Japanese Patients

The Epidemiology of Major Depressive Disorder

2003 • 7,767 citations

Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

1996 • 5,154 citations

Allelic Variation of Human Serotonin Transporter Gene Expression

1996 • 2,225 citations

Use of Unlinked Genetic Markers to Detect Population Stratification in Association Studies

1999 • 1,226 citations

Pharmacokinetics of selective serotonin reuptake inhibitors

2000 • 826 citations

DEFINITION AND EPIDEMIOLOGY OF TREATMENT-RESISTANT DEPRESSION

1996 • 764 citations

Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine

1998 • 605 citations

The 5-HT3B subunit is a major determinant of serotonin-receptor function

1999 • 555 citations

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders in Primary Care

2007 • 473 citations

CYP2D6 and CYP2C19 genotype‐based dose recommendations for antidepressants: a first step towards subpopulation‐specific dosages

2001 • 429 citations

Allelic Variation in the Serotonin Transporter Promoter Affects Onset of Paroxetine Treatment Response in Late-Life Depression

2000 • 410 citations

Serotonin transporter gene polymorphism and antidepressant response

2000 • 392 citations

Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder

1997 • 305 citations

Inhibition of P-Glycoprotein by Newer Antidepressants

2003 • 290 citations

Pharmacogenetics of Antidepressant Medication Intolerance

2003 • 284 citations

The Pharmacological and Functional Characteristics of the Serotonin 5-HT3A Receptor Are Specifically Modified by a 5-HT3B Receptor Subunit

1999 • 278 citations

The –1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity

2004 • 254 citations

A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter

1998 • 254 citations

Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders

2002 • 251 citations

Investigation of serotonin-related genes in antidepressant response

2004 • 234 citations

Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluvoxamine in Japanese depressed patients

2002 • 227 citations

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Bipolar Disorders, Part I: Treatment of Bipolar Depression

2002 • 189 citations

Serotonin-2A-receptor and -transporter polymorphisms: lack of association in patients with major depression

2001 • 188 citations

Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder

2005 • 184 citations

Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species.

1995 • 179 citations

Prediction of Antidepressant Response to Milnacipran by Norepinephrine Transporter Gene Polymorphisms

2004 • 159 citations

Variations in the 5-Hydroxytryptamine Type 3B Receptor Gene as Predictors of the Efficacy of Antiemetic Treatment in Cancer Patients

2003 • 157 citations

Association between the 5′ UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder

2001 • 129 citations

Cloning and functional expression of a human 5-hydroxytryptamine type 3AS receptor subunit.

1995 • 117 citations

Serotonin-2 Receptors and Human Sleep Effect of a Selective Antagonist on EEG Power Spectra

1999 • 111 citations

Functional promoter polymorphism of the human serotonin transporter

1997 • 108 citations

Serotonin Receptor 2A Gene Polymorphism (–1438A/G) and Short-Term Treatment Response to Citalopram

2005 • 105 citations

Influence of monoamine oxidase A and serotonin receptor 2A polymorphisms in SSRI antidepressant activity

2002 • 100 citations

Serotonin transporter gene (5-HTTLPR) is not associated with depressive symptomatology in mood disorders

1999 • 99 citations

A Double-Blind Comparison of Fluvoxamine and Paroxetine in the Treatment of Depressed Outpatients

1997 • 89 citations

A Polymorphism in the Serotonin Receptor 3A (HTR3A) Gene and Its Association With Harm Avoidance in Women

2003 • 87 citations

The pharmacogenomics of selective serotonin reuptake inhibitors

2004 • 83 citations

Controlled clinical comparison of paroxetine and fluvoxamine considering the serotonin transporter promoter polymorphism

2005 • 78 citations

Association between -1438G/A Promoter Polymorphism in the 5-HT<sub>2A</sub> Receptor Gene and Fluvoxamine Response in Japanese Patients with Major Depressive Disorder

2002 • 77 citations

Polymorphisms in the 5-Hydroxytryptamine 2A Receptor and CytochromeP4502D6 Genes Synergistically Predict Fluvoxamine-Induced Side Effects in Japanese Depressed Patients

2005 • 74 citations

Distribution and characterization of the [3H]granisetron-labelled 5-HT3 receptor in the human forebrain

1993 • 66 citations

Investigation of the human serotonin receptor gene HTR3B in bipolar affective and schizophrenic patients

2004 • 53 citations

T102C and –1438 G/A polymorphisms of the 5-HT2A receptor gene in Turkish patients with obsessive–compulsive disorder

2003 • 49 citations

Plasma Tryptophan to Large Neutral Amino Acids Ratio and Therapeutic Response to a Selective Serotonin Uptake Inhibitor

1994 • 48 citations

LY367265, an inhibitor of the 5-hydroxytryptamine transporter and 5-hydroxytryptamine2A receptor antagonist: a comparison with the antidepressant, nefazodone

2000 • 48 citations

Pharmacological characterization of the 5‐HT receptors mediating contraction and relaxation of canine isolated proximal stomach smooth muscle

2002 • 41 citations

Monoamine Oxidase A Gene Polymorphism, 5-HT<sub>2A</sub> Receptor Gene Polymorphism and Incidence of Nausea Induced by Fluvoxamine

2003 • 35 citations

Long-term treatment with antidepressants in primary care

1998 • 24 citations

Controlled comparison of paroxetine and fluvoxamine in major depression

1994 • 23 citations

Molecular Cloning of Alternatively Spliced Human 5‐HT₃ Receptor cDNAs^a

1998 • 17 citations

The interaction of antidepressant drugs with neurotransmitter receptor bidning sites and 5-HT uptake sites in human brain in vitro

1993 • 6 citations