T-Lymphocyte—Activating Properties of Epidermal Antigen-Presenting Cells from Normal and Psoriatic Skin: Evidence that Psoriatic Epidermal Antigen-Presenting Cells Resemble Cultured Normal Langerhans Cells

Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro.

1985 • 1,141 citations

Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB.

1980 • 983 citations

Immunologic Functions of Ia-Bearing Epidermal Langerhans Cells

1978 • 732 citations

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.

1987 • 592 citations

Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells.

1989 • 542 citations

Psoriasis: a disease of abnormal Keratinocyte proliferation induced by T lymphocytes

1986 • 335 citations

Role of Growth Factors, Cytokines, and Their Receptors in the Pathogenesis of Psoriasis

1990 • 248 citations

Expression of HLA-DR molecules by keratinocytes, and presence of Langerhans cells in the dermal infiltrate of active psoriatic plaques.

1986 • 196 citations

Effects of ultraviolet radiation on human epidermal cell alloantigen presentation: initial depression of Langerhans cell-dependent function is followed by the appearance of T6- Dr+ cells that enhance epidermal alloantigen presentation.

1985 • 189 citations

Low-dose cyclosporin A in severe psoriasis. A double-blind study

1988 • 187 citations

In vitro evidence that Langerhans cells can adopt two functionally distinct forms capable of antigen presentation to T lymphocytes.

1989 • 177 citations

Psoriatic Epidermal Cells Demonstrate Increased Numbers and Function of Non-Langerhans Antigen-presenting Cells

1989 • 105 citations

Functional Dichotomy between Langerhans Cells that Present Antigen to Naive and to Memory/Effector T Lymphocytes

1990 • 104 citations

Intralesional cyclosporine in the treatment of psoriasis

1990 • 99 citations

Langerhans Cells: Antigen Presenting Cells of the Epidermis

1984 • 90 citations

Effectiveness of cyclosporine treatment in severe psoriasis: A clinical and immunologic study

1989 • 58 citations

The immune functions of epidermal cells.

1989 • 58 citations

Comparison of Effects of Transforming Growth Factor-Beta and Cyclosporin A on Antigen-Presenting Cells of Blood and Epidermis

1991 • 52 citations

Keratinocyte proliferation in wound healing and skin diseases

1988 • 46 citations

Cutaneous T-Cell Lymphoma Lesional Epidermal Cells Activate Autologous CD4+ T Lymphocytes: Involvement of Both CD1+OKM5+ and CD1+OKM5− Antigen-Presenting Cells

1990 • 38 citations

Stimulation of T cells by autologous mononuclear leukocytes and epidermal cells in psoriasis

1986 • 34 citations

Keratinocyte expression of OKM5 antigen in inflammatory cutaneous disease

1989 • 30 citations

Expression of OKM5 Antigen on Epidermal Cells in Mycosis Fungoides Plaque Stage

1988 • 28 citations

Reduced density of T6-positive epidermal Langerhans´ cells in uninvolved skin of patients with psoriasis

1987 • 17 citations

Keratinocyte and epidermal leukocyte expression of CD36 (OKM5) in benign and malignant skin diseases

1990 • 17 citations

Speculations on the Immunopathogenesis of Psoriasis: T-Cell Violation of a Keratinocyte Sphere of Influence

1990 • 15 citations

The Biochemistry of Skin Disease: Psoriasis

1971 • 11 citations