Substitution of glutamine-60 with glutamic acid causes the lac permease of Escherichia coli to become temperature sensitive

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

A complementation analysis of the restriction and modification of DNA in Escherichia coli

1969 • 3,866 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

1981 • 868 citations

[13] Bacterial Membranes

1971 • 653 citations

Sequence of the lactose permease gene

1980 • 501 citations

Structure of the lac carrier protein of Escherichia coli.

1983 • 299 citations

The electrochemical gradient of protons and its relationship to active transport in Escherichia coli membrane vesicles.

1976 • 296 citations

Lactose Carrier Protein of Escherichia coli Structure and Expression of Plasmids Carrying the Y Gene of the lac Operon

1980 • 262 citations

The relation between the electrochemical proton gradient and active transport in Escherichia coli membrane vesicles

1977 • 218 citations

A new method for the purification and identification of covalently closed circular DNA molecules

1978 • 210 citations

The electrochemical proton gradient in Escherichia coli membrane vesicles

1977 • 208 citations

TheLac carrier protein inEscherichia coli

1983 • 179 citations

Localization of D-lactate dehydrogenase in native and reconstituted Escherichia coli membrane vesicles

1975 • 167 citations

[72] Transport in isolated bacterial membrane vesicles

1974 • 165 citations

Amplification of the lactose carrier protein in Escherichia coli using a plasmid vector

1978 • 161 citations

Effect of single amino acid replacements on the thermal stability of the NH2-terminal domain of phage lambda repressor.

1984 • 153 citations

Site-directed mutagenesis of cys148 in the lac carrier protein of Escherichia coli

1984 • 85 citations

Purified reconstituted lac carrier protein from Escherichia coli is fully functional.

1984 • 83 citations

Functional and immunochemical characterization of a mutant of Escherichia coli energy uncoupled for lactose transport

1985 • 66 citations

Lactose permease: a carrier on the move

1983 • 45 citations

Proton Electrochemical Gradients and Active Transport: The Saga of lac Permease

1985 • 31 citations