Proton Electrochemical Gradients and Active Transport: The Saga of lac Permease

Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism

1961 • 4,416 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

Specific labeling and partial purification of the M protein, a component of the beta-galactoside transport system of Escherichia coli.

1965 • 374 citations

Methods in Protein Sequence Analysis

1982 • 190 citations

TheLac carrier protein inEscherichia coli

1983 • 179 citations

Molecular biology and energetics of membrane transport

1976 • 166 citations

Intramolecular dislocation of the COOH terminus of the lac carrier protein in reconstituted proteoliposomes.

1984 • 114 citations

Peptide-specific antibody locates the COOH terminus of the lactose carrier of Escherichia coli on the cytoplasmic side of the plasma membrane.

1983 • 103 citations

Monoclonal antibodies against the lac carrier protein from Escherichia coli. 2. Binding studies with membrane vesicles and proteoliposomes reconstituted with purified lac carrier protein

1984 • 96 citations

Reconstitution of active transport in proteoliposomes containing cytochrome o oxidase and lac carrier protein purified from Escherichia coli.

1983 • 88 citations

Monoclonal antibodies against the lac carrier protein from Escherichia coli. 1. Functional studies

1984 • 86 citations

Mechanism of lactose translocation in proteoliposomes reconstituted with lac carrier protein purified from Escherichia coli. I. Effect of pH and imposed membrane potential on efflux, exchange, and counterflow

1983 • 85 citations

Site-directed mutagenesis of cys148 in the lac carrier protein of Escherichia coli

1984 • 85 citations

Purified reconstituted lac carrier protein from Escherichia coli is fully functional.

1984 • 83 citations

Topology of the lac carrier protein in the membrane of Escherichia coli.

1983 • 79 citations

Sidedness of native membrane vesicles of Escherichia coli and orientation of the reconstituted lactose :H⁺ carrier

1984 • 79 citations

Mechanism of lactose translocation in proteoliposomes reconstituted with lac carrier protein purified from Escherichia coli. II. Deuterium solvent isotope effects

1983 • 77 citations

Energy Coupling in the Lactose Transport System of Escherichia coli

1970 • 59 citations

Mutations in the lacY gene of Escherichia coli define functional organization of lactose permease.

1981 • 57 citations

An ecf mutation in Escherichia coli pleiotropically affecting energy coupling in active transport but not generation or maintenance of membrane potential

1977 • 56 citations

Morphology of proteoliposomes reconstituted with purified lac carrier protein from Escherichia coli.

1984 • 46 citations

Lactose permease: a carrier on the move

1983 • 45 citations

Does the lactose carrier of Escherichia coli function as a monomer?

1983 • 35 citations

The eup genetic locus of Escherichia coli and its role in H+/solute symport.

1981 • 30 citations

Identification of Internal Residues of Lactose Permease of Escherichia Coli by Radiolabel Sequencing of Peptide Mixtures

1982 • 22 citations