Inhibitors of calmodulin and protein kinase C block different phases of hippocampal long-term potentiation

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

1986 • 1,842 citations

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

1983 • 1,106 citations

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

1987 • 947 citations

Long-Term Potentiation

1987 • 804 citations

Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro

1988 • 800 citations

Potentiation of synaptic transmission in the hippocampus by phorbol esters

1986 • 647 citations

Translocation of Protein Kinase C Activity May Mediate Hippocampal Long-Term Potentiation

1986 • 532 citations

Anisomycin blocks the late phase of long-term potentiation in the dentate gyrus of freely moving rats

1984 • 508 citations

Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase.

1984 • 389 citations

Protein kinase C injection into hippocampal pyramidal cells elicits features of long term potentiation

1987 • 340 citations

The Neural and Molecular Bases of Learning

1988 • 304 citations

N‐methyl aspartate activates voltage‐dependent calcium conductance in rat hippocampal pyramidal cells.

1983 • 281 citations

R 24571: A new powerful inhibitor of red blood cell Ca++-transport ATPase and of calmodulin-regulated functions

1981 • 260 citations

Protein kinase C inhibitors eliminate hippocampal long-term potentiation

1987 • 252 citations

R 24 571: A potent inhibitor of calmodulin-activated enzymes

1981 • 241 citations

Polymyxin B, an inhibitor of protein kinase C, prevents the maintenance of synaptic long-term potentiation in hippocampal CA1 neurons

1988 • 178 citations

Phospholipid-sensitive Ca2+-dependent protein kinase: a major protein phosphorylation system

1984 • 120 citations

C-Kinase activation prolongs Ca2+-dependent inactivation of K+ currents

1986 • 102 citations

Trifluoperazine inhibits hippocampal long-term potentiation and the phosphorylation of a 40,000 dalton protein

1980 • 81 citations

Modulation of long-term potentiation: Effects of adrenergic and neuroleptic drugs

1982 • 78 citations

Interaction of calmodulin inhibitors and protein kinase C inhibitors with voltage-dependent calcium channels

1987 • 65 citations

Blockade of tetanic- and calcium-induced long-term potentiation in the hippocampal slice preparation by neuroleptics

1984 • 57 citations

Long-term potentiation of synaptic transmission in the hippocampus of the rat; effect of calmodulin and oleoyl-acetyl-glycerol on release of [3H]glutamate

1986 • 53 citations

Phorbol ester-induced hippocampal long-term potentiation is counteracted by inhibitors of protein kinase C

1988 • 48 citations

Tetanic stimulation affects the metabolism of phosphoinositides in hippocampal slices

1984 • 45 citations

Requirement of extracellular Ca2+ after tetanus for induction of long-term potentiation in guinea pig hippocampal slices

1987 • 32 citations

Alterations in calmodulin content in fractions of rat hippocampal slices during tetanic- and calcium-induced long-term potentiation

1988 • 22 citations