Autophosphorylation of αCaMKII is not a general requirement for NMDA receptor‐dependent LTP in the adult mouse

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Functional neurogenesis in the adult hippocampus

2002 • 2,813 citations

The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation.

1962 • 2,522 citations

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

The molecular basis of CaMKII function in synaptic and behavioural memory

2002 • 1,855 citations

Driving AMPA Receptors into Synapses by LTP and CaMKII: Requirement for GluR1 and PDZ Domain Interaction

2000 • 1,507 citations

Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice

1992 • 1,458 citations

cAMP-DEPENDENT PROTEIN KINASE: FRAMEWORK FOR A DIVERSE FAMILY OF REGULATORY ENZYMES

1990 • 1,121 citations

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

1983 • 1,106 citations

Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity

2000 • 1,085 citations

Autophosphorylation at Thr ²⁸⁶ of the α Calcium-Calmodulin Kinase II in LTP and Learning

1998 • 1,045 citations

Phosphorylation of the AMPA Receptor GluR1 Subunit Is Required for Synaptic Plasticity and Retention of Spatial Memory

2003 • 782 citations

NEURONAL Ca²⁺/CALMODULIN-DEPENDENT PROTEIN KINASES

1992 • 713 citations

Interaction with the NMDA receptor locks CaMKII in an active conformation

2001 • 695 citations

Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons

2002 • 631 citations

Modulation of AMPA receptor unitary conductance by synaptic activity

1998 • 531 citations

A mechanism for memory storage insensitive to molecular turnover: a bistable autophosphorylating kinase.

1985 • 470 citations

Inducible and Reversible Enhancement of Learning, Memory, and Long-Term Potentiation by Genetic Inhibition of Calcineurin

2001 • 464 citations

Gating of CaMKII by cAMP-Regulated Protein Phosphatase Activity During LTP

1998 • 452 citations

Neurobiology: Memory and molecular turnover

1984 • 377 citations

A developmental switch in the signaling cascades for LTP induction

2002 • 322 citations

Inhibitory Autophosphorylation of CaMKII Controls PSD Association, Plasticity, and Learning

2002 • 294 citations

Physiological identification and analysis of dentate granule cell responses to stimulation of the medial and lateral perforant pathways in the rat

1977 • 283 citations

Signaling from cAMP/PKA to MAPK and Synaptic Plasticity

2003 • 273 citations

Long-term potentiation in the dentate gyrus: induction and increased glutamate release are blocked by d(−)aminophosphonovalerate

1987 • 269 citations

Feasibility of long-term storage of graded information by the Ca2+/calmodulin-dependent protein kinase molecules of the postsynaptic density.

1988 • 261 citations

A molecular mechanism for long-term sensitization in Aplysia

1987 • 234 citations

Visualization of the Distribution of Autophosphorylated Calcium/Calmodulin-Dependent Protein Kinase II after Tetanic Stimulation in the CA1 Area of the Hippocampus

1997 • 234 citations

Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation.

1996 • 230 citations

Increased Phosphorylation of Ca2+/Calmodulin-dependent Protein Kinase II and Its Endogenous Substrates in the Induction of Long Term Potentiation

1995 • 228 citations

Regulatory subunits of cAMP-dependent protein kinases are degraded after conjugation to ubiquitin: a molecular mechanism underlying long-term synaptic plasticity.

1993 • 208 citations

Mechanisms for Generating the Autonomous cAMP-Dependent Protein Kinase Required for Long-Term Facilitation in Aplysia

1999 • 184 citations

Direct Evidence for Biphasic cAMP Responsive Element-Binding Protein Phosphorylation during Long-Term Potentiation in the Rat Dentate GyrusIn Vivo

1999 • 151 citations

DARPP-32, a dopamine- and adenosine 3‘:5‘-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.

1984 • 142 citations

Systematic mutational analysis of cAMP-dependent protein kinase identifies unregulated catalytic subunits and defines regions important for the recognition of the regulatory subunit.

1992 • 122 citations

The role of α-CaMKII autophosphorylation in neocortical experience-dependent plasticity

2000 • 119 citations

Autonomous activity of CaMKII is only transiently increased following the induction of long‐term potentiation in the rat hippocampus

2004 • 104 citations

Protein Phosphatase-1 Regulation in the Induction of Long-Term Potentiation: Heterogeneous Molecular Mechanisms

2000 • 99 citations

Neocortical Long-Term Potentiation and Experience-Dependent Synaptic Plasticity Require α-Calcium/Calmodulin-Dependent Protein Kinase II Autophosphorylation

2003 • 97 citations

Ca ²⁺ /calmodulin-dependent protein kinase II phosphorylation of the presynaptic protein synapsin I is persistently increased during long-term potentiation

1996 • 91 citations

CA1 Long-Term Potentiation Is Diminished but Present in Hippocampal Slices from α-CaMKII Mutant Mice

1998 • 88 citations

Hippocampal Synaptic Metaplasticity Requires Inhibitory Autophosphorylation of Ca²⁺/Calmodulin-Dependent Kinase II

2005 • 64 citations

Parallel kinase cascades are involved in the induction of LTP at hippocampal CA1 synapses

2003 • 58 citations

Subunit interaction sites between the regulatory and catalytic subunits of cAMP-dependent protein kinase. Identification of a specific interchain disulfide bond.

1988 • 34 citations