Structural Determination of Lipid-bound ApoA-I Using Fluorescence Resonance Energy Transfer

High density lipoprotein as a protective factor against coronary heart disease

1977 • 5,019 citations

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

1999 • 1,708 citations

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

1999 • 1,527 citations

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

1999 • 1,441 citations

Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI

1991 • 990 citations

Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation

1997 • 417 citations

Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice.

1994 • 372 citations

A Detailed Molecular Belt Model for Apolipoprotein A-I in Discoidal High Density Lipoprotein

1999 • 334 citations

The apolipoprotein multigene family: biosynthesis, structure, structure-function relationships, and evolution.

1988 • 315 citations

Apolipoprotein A-I: structure–function relationships

2000 • 293 citations

Structure and thermodynamic properties of high density lipoprotein recombinants.

1977 • 192 citations

Differentiation of lipid-associating helices by use of three-dimensional molecular hydrophobicity potential calculations

1991 • 181 citations

Molecular basis of exchangeable apolipoprotein function

2000 • 153 citations

Profluorescent protease substrates: intramolecular dimers described by the exciton model.

1996 • 140 citations

Predicting the structure of apolipoprotein A-I in reconstituted high-density lipoprotein disks

1997 • 138 citations

Structure and function of apolipoprotein A-I and high-density lipoprotein

2000 • 132 citations

The conformation of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles. 13C NMR studies of lysine ionization behavior.

1992 • 131 citations

The Structure of Human Lipoprotein A-I

1999 • 130 citations

Amphipathic helixes and plasma lipoproteins: Thermodynamic and geometric considerations

1977 • 122 citations

ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice

1998 • 114 citations

Truncation of the Amino Terminus of Human Apolipoprotein A-I Substantially Alters Only the Lipid-Free Conformation

1997 • 108 citations

Mode of assembly of amphipathic helical segments in model high-density lipoproteins

1990 • 106 citations

Regulation of lecithin cholesterol acyltransferase activity

1998 • 96 citations

Investigation of the lipid domains and apolipoprotein orientation in reconstituted high density lipoproteins by fluorescence and IR methods.

1990 • 81 citations

Structure of apolipoprotein A-I in three homogeneous, reconstituted high density lipoprotein particles.

1990 • 81 citations

The Hydrophobic Face Orientation of Apolipoprotein A-I Amphipathic Helix Domain 143–164 Regulates Lecithin:Cholesterol Acyltransferase Activation

1998 • 68 citations

HIGH-DENSITY LIPOPROTEIN AND ATHEROSCLEROSIS

1975 • 53 citations

HDL Deficiency in Genetically Engineered Mice Requires Elevated LDL to Accelerate Atherogenesis

1997 • 52 citations

[35] Use of cross-linking reagents to study lipoprotein structure

1986 • 50 citations

Alteration in Apolipoprotein A-I 22-Mer Repeat Order Results in a Decrease in Lecithin:Cholesterol Acyltransferase Reactivity

1997 • 49 citations

Stereospecific reaction of muscle fiber proteins with the 5' or 6' isomer of (iodoacetamido)tetramethylrhodamine

1992 • 44 citations

The Orientation of Helix 4 in Apolipoprotein A-I-containing Reconstituted High Density Lipoproteins

2000 • 40 citations

High level secretion of wild-type and mutant forms of human proapoA-I using baculovirus-mediated Sf-9 cell expression

1996 • 40 citations

Distinct Central Amphipathic α-Helices in Apolipoprotein A-I Contribute to the in Vivo Maturation of High Density Lipoprotein by Either Activating Lecithin-Cholesterol Acyltransferase or Binding Lipids

2000 • 39 citations

Single Repeat Deletion in ApoA-I Blocks Cholesterol Esterification and Results in Rapid Catabolism of Δ6 and Wild-type ApoA-I in Transgenic Mice

2000 • 39 citations

Location and dynamics of a membrane-bound fluorescent hapten. A spectroscopic study

1984 • 37 citations

Dynamic nature of the quaternary structure of the vesicular stomatitis virus envelope glycoprotein

1990 • 31 citations

Proximity Relationships between Engineered Cysteine Residues in Chicken Skeletal Myosin Regulatory Light Chain:

1995 • 13 citations

Labeling of the cytoplasmic domain of the influenza virus hemagglutinin with fluorescein reveals sites of interaction with membrane lipid bilayers

1985 • 12 citations

The Transformation of Nascent Disc Shaped High Density Lipoproteins into Mature Spherical High Density Lipoproteins: Conformational Analysis of Apolipoprotein A-I in Model Intermediate Particles

1994 • 5 citations