Efficient Processing of Primary microRNA Hairpins by Drosha Requires Flanking Nonstructured RNA Sequences

MicroRNAs

2004 • 33,206 citations

The nuclear RNase III Drosha initiates microRNA processing

2003 • 4,966 citations

Role for a bidentate ribonuclease in the initiation step of RNA interference

2001 • 4,804 citations

MicroRNAs Modulate Hematopoietic Lineage Differentiation

2003 • 3,241 citations

The Microprocessor complex mediates the genesis of microRNAs

2004 • 2,625 citations

Processing of primary microRNAs by the Microprocessor complex

2004 • 2,617 citations

The Drosha-DGCR8 complex in primary microRNA processing

2004 • 2,096 citations

Identification of Mammalian microRNA Host Genes and Transcription Units

2004 • 1,966 citations

Single Processing Center Models for Human Dicer and Bacterial RNase III

2004 • 985 citations

Solubilization and Purification of Enzymatically Active Glutathione S-Transferase (pGEX) Fusion Proteins

1993 • 891 citations

Both Natural and Designed Micro RNAs Can Inhibit the Expression of Cognate mRNAs When Expressed in Human Cells

2002 • 824 citations

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

2002 • 622 citations

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

2004 • 554 citations

Sequence requirements for micro RNA processing and function in human cells

2003 • 538 citations

Ribonuclease activity and RNA binding of recombinant human Dicer

2002 • 449 citations

RNAi: A Guide to Gene Silencing

2003 • 141 citations

The RNase III Family: A Conserved Structure and Expanding Functions in Eukaryotic dsRNA Metabolism

2001 • 100 citations

Regulation of ribonuclease III processing by double-helical sequence antideterminants

1997 • 92 citations

Recognition of a conserved class of RNA tetraloops by Saccharomyces cerevisiae RNase III

2000 • 83 citations

Recognition of a conserved class of RNA tetraloops by Saccharomyces cerevisiae RNase III

2000 • 68 citations

Substrate recognition by a eukaryotic RNase III: The double-stranded RNA-binding domain of Rnt1p selectively binds RNA containing a 5′-AGNN-3′ tetraloop

2000 • 62 citations

Evaluation of the RNA Determinants for Bacterial and Yeast RNase III Binding and Cleavage

2004 • 50 citations

Sequence Dependence of Substrate Recognition and Cleavage by Yeast RNase III

2003 • 41 citations