Sequence Dependence of Substrate Recognition and Cleavage by Yeast RNase III

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1989 • 1,072 citations

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A conserved double-stranded RNA-binding domain.

1992 • 540 citations

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1998 • 464 citations

The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized

1999 • 419 citations

RNA-binding protein Nrd1 directs poly(A)-independent 3′-end formation of RNA polymerase II transcripts

2001 • 365 citations

RNA recognition by a Staufen double-stranded RNA-binding domain

2000 • 360 citations

Yeast Exosome Mutants Accumulate 3′-Extended Polyadenylated Forms of U4 Small Nuclear RNA and Small Nucleolar RNAs

2000 • 354 citations

Structural origins of gentamicin antibiotic action

1998 • 354 citations

A simple and efficient method to reduce nontemplated nucleotide addition at the 3′ terminus of RNAs transcribed by T7 RNA polymerase

1999 • 315 citations

Preparation of¹³C and¹⁵N labelled RNAs for heteronuclear multi-dimensional NMR studies

1992 • 302 citations

Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation

1998 • 299 citations

Structure of the dsRNA binding domain of E. coli RNase III.

1995 • 279 citations

Germline development in vertebrates and invertebrates

1999 • 274 citations

Preparation of isotopically labeled ribonucleotides for multidimensional NMR spectroscopy of RNA

1992 • 271 citations

NMR solution structure of a dsRNA binding domain from Drosophila staufen protein reveals homology to the N-terminal domain of ribosomal protein S5.

1995 • 262 citations

RNAi and double-strand RNA

1999 • 242 citations

Proteins binding to duplexed RNA: one motif, multiple functions

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Function, mechanism and regulation of bacterial ribonucleases

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RNase III Cleaves Eukaryotic Preribosomal RNA at a U3 snoRNP-Dependent Site

1996 • 230 citations

Crystallographic and Modeling Studies of RNase III Suggest a Mechanism for Double-Stranded RNA Cleavage

2001 • 230 citations

PKR—A protein kinase regulated by double-stranded RNA

1997 • 207 citations

Yeast RNase III as a key processing enzyme in small nucleolar RNAs metabolism

1998 • 175 citations

Control of developmental timing by small temporal RNAs: a paradigm for RNA‐mediated regulation of gene expression

2002 • 173 citations

Processing of a dicistronic small nucleolar RNA precursor by the RNA endonuclease Rnt1

1998 • 165 citations

Seven Novel Methylation Guide Small Nucleolar RNAs Are Processed from a Common Polycistronic Transcript by Rat1p and RNase III in Yeast

1999 • 162 citations

Yeast Rnt1p is required for cleavage of the pre-ribosomal RNA in the 3′ ETS but not the 5′ ETS

1999 • 145 citations

Depletion of yeast RNase III blocks correct U2 3' end formation and results in polyadenylated but functional U2 snRNA

1998 • 123 citations

Alternative 3′-end processing of U5 snRNA by RNase III

1997 • 114 citations

The RNase III Family: A Conserved Structure and Expanding Functions in Eukaryotic dsRNA Metabolism

2001 • 100 citations

Binding of the Protein Kinase PKR to RNAs with Secondary Structure Defects: Role of the Tandem A−G Mismatch and Noncontiguous Helixes

1998 • 97 citations

The regulation of the protein kinase PKR by RNA

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Staufen: a common component of mRNA transport in oocytes and neurons?

2000 • 94 citations

Regulation of ribonuclease III processing by double-helical sequence antideterminants

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Recognition of a conserved class of RNA tetraloops by Saccharomyces cerevisiae RNase III

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U1 snRNA is cleaved by RNase III and processed through an Sm site-dependent pathway

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11 RNAi (nematodes: Caenorhabditis elegans)

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Ribonuclease III: new sense from nuisance

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The Putative Nucleic Acid Helicase Sen1p Is Required for Formation and Stability of Termini and for Maximal Rates of Synthesis and Levels of Accumulation of Small Nucleolar RNAs in Saccharomyces cerevisiae

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Defining the enzyme binding domain of a ribonuclease III processing signal. Ethylation interference and hydroxyl radical footprinting using catalytically inactive RNase III mutants.

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Intrinsic Double-Stranded-RNA Processing Activity of Escherichia coli Ribonuclease III Lacking the dsRNA-Binding Domain

2001 • 62 citations

Substrate recognition by a eukaryotic RNase III: The double-stranded RNA-binding domain of Rnt1p selectively binds RNA containing a 5′-AGNN-3′ tetraloop

2000 • 62 citations

The N-Terminal Domain That Distinguishes Yeast from Bacterial RNase III Contains a Dimerization Signal Required for Efficient Double-Stranded RNA Cleavage

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[14] Biochemical and NMR studies of RNA conformation with an emphasis on RNA pseudoknots

1995 • 52 citations

Mutational analysis of a ribonuclease III processing signal

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Solution structure of conserved AGNN tetraloops: insights into Rnt1p RNA processing

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Separate pathways for excision and processing of 16S and 23S rRNA from the primary rRNA operon transcript from the hyperthermophilic archaebacterium Sulfolobus acldocaldarius: similarities to eukaryotic rRNA processing

1994 • 44 citations

A conserved sequence element in ribonuclease III processing signals is not required for accuratein vitroenzymatic cleavage

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Purification and Characterization of Saccharomyces cerevisiae Rnt1p Nuclease

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Unexpected Electrophoretic Migration of RNA with Different 3‘ Termini Causes a RNA Sizing Ambiguity That Can Be Resolved Using Nuclease P1-Generated Sequencing Ladders

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Structural characterization of a ribonuclease III processing signal

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Double-stranded RNA binding proteins and their substrates.

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