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Processing of primary microRNAs by the Microprocessor complex

Data up to Jan 2025

Published2004
Citations2,617
References29

Total Citations Per Year

Abstract

References (29)

The nuclear RNase III Drosha initiates microRNA processing

2003 • 4,966 citations

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

2000 • 4,834 citations

Role for a bidentate ribonuclease in the initiation step of RNA interference

2001 • 4,804 citations

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

2003 • 2,893 citations

Asymmetry in the Assembly of the RNAi Enzyme Complex

2003 • 2,761 citations

Nuclear Export of MicroRNA Precursors

2003 • 2,662 citations

The Microprocessor complex mediates the genesis of microRNAs

2004 • 2,625 citations

A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA

2001 • 2,623 citations

MicroRNA maturation: stepwise processing and subcellular localization

2002 • 2,410 citations

A Protein Interaction Map of Drosophila melanogaster

2003 • 2,294 citations

Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing

2001 • 1,847 citations

Role of MicroRNAs in Plant and Animal Development

2003 • 1,765 citations

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

2001 • 1,761 citations

MicroRNA-Directed Cleavage of HOXB8 mRNA

2004 • 1,680 citations

Cleavage of Scarecrow-like mRNA Targets Directed by a Class of Arabidopsis miRNA

2002 • 1,569 citations

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

2004 • 1,370 citations

siRNAs can function as miRNAs

2003 • 1,252 citations

The lin-4 Regulatory RNA Controls Developmental Timing in Caenorhabditis elegans by Blocking LIN-14 Protein Synthesis after the Initiation of Translation

1999 • 1,174 citations

Single Processing Center Models for Human Dicer and Bacterial RNase III

2004 • 985 citations

Both Natural and Designed Micro RNAs Can Inhibit the Expression of Cognate mRNAs When Expressed in Human Cells

2002 • 824 citations

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

2003 • 690 citations

Fragile X-related protein and VIG associate with the RNA interference machinery

2002 • 646 citations

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

2003 • 569 citations

The dsRNA Binding Protein RDE-4 Interacts with RDE-1, DCR-1, and a DExH-Box Helicase to Direct RNAi in C. elegans

2002 • 538 citations

The Arabidopsis double-stranded RNA-binding protein HYL1 plays a role in microRNA-mediated gene regulation

2004 • 504 citations

A micrococcal nuclease homologue in RNAi effector complexes

2003 • 451 citations

Human RNase III Is a 160-kDa Protein Involved in Preribosomal RNA Processing

2000 • 193 citations

Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region

2003 • 134 citations

Redistribution of U-snRNPs during mitosis

1986 • 108 citations

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Processing of primary microRNAs by the Microprocessor complex (2004) – Nature | Metascience Observatory Explorer