The Drosha-DGCR8 complex in primary microRNA processing

MicroRNAs

2004 • 33,206 citations

The nuclear RNase III Drosha initiates microRNA processing

2003 • 4,966 citations

Role for a bidentate ribonuclease in the initiation step of RNA interference

2001 • 4,804 citations

MicroRNA genes are transcribed by RNA polymerase II

2004 • 4,200 citations

RNA interference is mediated by 21- and 22-nucleotide RNAs

2001 • 3,271 citations

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

2003 • 2,893 citations

Asymmetry in the Assembly of the RNAi Enzyme Complex

2003 • 2,761 citations

Nuclear Export of MicroRNA Precursors

2003 • 2,662 citations

A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA

2001 • 2,623 citations

Functional siRNAs and miRNAs Exhibit Strand Bias

2003 • 2,516 citations

MicroRNA maturation: stepwise processing and subcellular localization

2002 • 2,410 citations

Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing

2001 • 1,847 citations

A uniform system for microRNA annotation

2003 • 1,841 citations

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

2001 • 1,761 citations

Identification of Virus-Encoded MicroRNAs

2004 • 1,571 citations

Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi

2001 • 1,492 citations

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

2004 • 1,370 citations

Distinct Roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA Silencing Pathways

2004 • 1,254 citations

Single Processing Center Models for Human Dicer and Bacterial RNase III

2004 • 985 citations

A Role for the RNase III Enzyme DCR-1 in RNA Interference and Germ Line Development in Caenorhabditis elegans

2001 • 853 citations

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

2003 • 690 citations

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

2002 • 622 citations

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

2002 • 573 citations

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

2003 • 569 citations

Sequence requirements for micro RNA processing and function in human cells

2003 • 538 citations

The dsRNA Binding Protein RDE-4 Interacts with RDE-1, DCR-1, and a DExH-Box Helicase to Direct RNAi in C. elegans

2002 • 538 citations

Structure and conserved RNA binding of the PAZ domain

2003 • 468 citations

Ribonuclease activity and RNA binding of recombinant human Dicer

2002 • 449 citations

Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

2003 • 442 citations

miRNAs on the move: miRNA biogenesis and the RNAi machinery

2004 • 395 citations

MicroRNA precursors in motion: exportin-5 mediates their nuclear export

2004 • 273 citations

Crystallographic and Modeling Studies of RNase III Suggest a Mechanism for Double-Stranded RNA Cleavage

2001 • 230 citations

Human let-7 stem-loop precursors harbor features of RNase III cleavage products

2003 • 164 citations

Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region

2003 • 134 citations