Localization and modulation of ErbB receptor tyrosine kinases

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

1997 • 1,371 citations

RING Finger Proteins

2000 • 1,216 citations

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1999 • 1,134 citations

The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase

1999 • 1,045 citations

Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1

1999 • 1,000 citations

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

1998 • 865 citations

Structure of a c-Cbl–UbcH7 Complex

2000 • 824 citations

Kinesin Superfamily Motor Protein KIF17 and mLin-10 in NMDA Receptor-Containing Vesicle Transport

2000 • 700 citations

A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain

1998 • 548 citations

Decorin Is a Biological Ligand for the Epidermal Growth Factor Receptor

1999 • 376 citations

Regulation of Neuregulin Signaling by PSD-95 Interacting with ErbB4 at CNS Synapses

2000 • 376 citations

The LIN-2/LIN-7/LIN-10 Complex Mediates Basolateral Membrane Localization of the C. elegans EGF Receptor LET-23 in Vulval Epithelial Cells

1998 • 366 citations

Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.

2000 • 345 citations

Ligand-induced Ubiquitination of the Epidermal Growth Factor Receptor Involves the Interaction of the c-Cbl RING Finger and UbcH7

1999 • 328 citations

The RING Finger of c-Cbl Mediates Desensitization of the Epidermal Growth Factor Receptor

1999 • 308 citations

ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor

2000 • 289 citations

Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor.

1998 • 278 citations

LIN-10 Is a Shared Component of the Polarized Protein Localization Pathways in Neurons and Epithelia

1998 • 271 citations

LET-23 Receptor Localization by the Cell Junction Protein LIN-7 during C. elegans Vulval Induction

1996 • 268 citations

The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses

2000 • 261 citations

An Autoregulatory Cascade of EGF Receptor Signaling Patterns the Drosophila Egg

1998 • 247 citations

Interaction between the Adhesion Receptor, CD44, and the Oncogene Product, p185 , Promotes Human Ovarian Tumor Cell Activation

1997 • 243 citations

The Transmembrane Molecule Kekkon 1 Acts in a Feedback Loop to Negatively Regulate the Activity of the Drosophila EGF Receptor during Oogenesis

1999 • 210 citations

Sustained Down-regulation of the Epidermal Growth Factor Receptor by Decorin

2000 • 210 citations

Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1

2000 • 200 citations

An Intramembrane Modulator of the ErbB2 Receptor Tyrosine Kinase That Potentiates Neuregulin Signaling

1999 • 197 citations

Identification of an Evolutionarily Conserved Heterotrimeric Protein Complex Involved in Protein Targeting

1998 • 193 citations

The formation of neuromuscular synapses

1998 • 189 citations

Threonine Phosphorylation Diverts Internalized Epidermal Growth Factor Receptors from a Degradative Pathway to the Recycling Endosome

2000 • 179 citations

Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapses.

1995 • 172 citations

The Evolutionarily Conserved N-terminal Region of Cbl Is Sufficient to Enhance Down-regulation of the Epidermal Growth Factor Receptor

2000 • 143 citations

Cd44 Enhances Neuregulin Signaling by Schwann Cells

2000 • 143 citations

Ligand Discrimination in Signaling through an ErbB4 Receptor Homodimer

2000 • 128 citations

TheDrosophila kekkonGenes: Novel Members of both the Leucine-Rich Repeat and Immunoglobulin Superfamilies Expressed in the CNS

1996 • 109 citations

Basolateral Localization of theCaenorhabditis elegansEpidermal Growth Factor Receptor in Epithelial Cells by the PDZ Protein LIN-10

1999 • 107 citations

Ligand discrimination by ErbB receptors: differential signaling through differential phosphorylation site usage

2000 • 98 citations

Differential signaling and regulation of apical vs. basolateral EGFR in polarized epithelial cells

1998 • 80 citations

c-Cbl Is a Suppressor of the Neu Oncogene

2000 • 74 citations

Multiple facets of sialomucin complex/MUC4, a membrane mucin and ErbB2 ligand, in tumors and tissues (Y2K update)

2000 • 73 citations

The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses

2000 • 72 citations

EGF receptor residues Leu679, Leu680 mediate selective sorting of ligand-receptor complexes in early endosomal compartments

2000 • 66 citations

Glucocorticoid-induced Functional Polarity of Growth Factor Responsiveness Regulates Tight Junction Dynamics in Transformed Mammary Epithelial Tumor Cells

1995 • 55 citations

E3-13.7 Integral Membrane Proteins Encoded by Human Adenoviruses Alter Epidermal Growth Factor Receptor Trafficking by Interacting Directly with Receptors in Early Endosomes

2000 • 37 citations

Regulation of EGF signaling by cell polarity in MDCK kidney epithelial cells

1999 • 22 citations

Membrane receptor location defines receptor interaction with signaling proteins in a polarized epithelium

1999 • 21 citations