Ligand Discrimination in Signaling through an ErbB4 Receptor Homodimer

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

Signaling Through Scaffold, Anchoring, and Adaptor Proteins

1997 • 2,268 citations

Dimerization of cell surface receptors in signal transduction

1995 • 1,631 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

Specificity within the EGF family/ErbB receptor family signaling network

1998 • 804 citations

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand‐receptor interactions

1997 • 719 citations

A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling

1994 • 601 citations

Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å

1996 • 589 citations

Efficiency of signalling through cytokine receptors depends critically on receptor orientation

1998 • 543 citations

Neuregulins and Their Receptors: A Versatile Signaling Module in Organogenesis and Oncogenesis

1997 • 471 citations

Heregulin induces tyrosine phosphorylation of HER4/p180erbB4

1993 • 445 citations

Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

1998 • 423 citations

Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases

1997 • 390 citations

Structure of the FGF Receptor Tyrosine Kinase Domain Reveals a Novel Autoinhibitory Mechanism

1996 • 376 citations

Multiple positive and negative regulators of signaling by the EGF-receptor

1999 • 330 citations

ErbB-1 and ErbB-2 Acquire Distinct Signaling Properties Dependent upon Their Dimerization Partner

1998 • 259 citations

The PTB domain: a new protein module implicated in signal transduction

1995 • 249 citations

Epidermal growth factor and transforming growth factor-alpha: differential intracellular routing and processing of ligand-receptor complexes.

1991 • 247 citations

The Transmembrane Molecule Kekkon 1 Acts in a Feedback Loop to Negatively Regulate the Activity of the Drosophila EGF Receptor during Oogenesis

1999 • 210 citations

Alternative Intracellular Routing of ErbB Receptors May Determine Signaling Potency

1998 • 208 citations

An Intramembrane Modulator of the ErbB2 Receptor Tyrosine Kinase That Potentiates Neuregulin Signaling

1999 • 197 citations

Receptor signaling: When dimerization is not enough

1999 • 179 citations

Neuregulins and their receptors

1995 • 178 citations

Heregulin Stimulates Mitogenesis and Phosphatidylinositol 3-Kinase in Mouse Fibroblasts Transfected with erbB2/neu and erbB3

1995 • 141 citations

Activation of Neu (ErbB-2) Mediated by Disulfide Bond-Induced Dimerization Reveals a Receptor Tyrosine Kinase Dimer Interface

1998 • 105 citations

Differential Signaling by the Epidermal Growth Factor-like Growth Factors Neuregulin-1 and Neuregulin-2

1998 • 87 citations

Proxy activation of protein ErbB2 by heterologous ligands implies a heterotetrameric mode of receptor tyrosine kinase interaction

1998 • 60 citations

Structural analysis of p185c-neu and epidermal growth factor receptor tyrosine kinases: oligomerization of kinase domains.

1996 • 47 citations

Superagonistic behaviour of epidermal growth factor/transforming growth factor-α chimaeras: correlation with receptor routing after ligand-induced internalization

1997 • 29 citations