The Drosophila Brahma (SWI/SNF) chromatin remodeling complex exhibits cell-type specific activation and repression functions

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Rb Interacts with Histone Deacetylase to Repress Transcription

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brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

1992 • 951 citations

ATP-Dependent Nucleosome Remodeling

2002 • 779 citations

ATP-Dependent Chromatin-Remodeling Complexes

2000 • 734 citations

Exit from G1 and S Phase of the Cell Cycle Is Regulated by Repressor Complexes Containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

2000 • 650 citations

Reconstitution of a Core Chromatin Remodeling Complex from SWI/SNF Subunits

1999 • 608 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

GENES AFFECTING THE REGULATION OF SUC2 GENE EXPRESSION BY GLUCOSE REPRESSION IN SACCHAROMYCES CEREVISIAE

1984 • 567 citations

Binding and Stimulation of HIV-1 Integrase by a Human Homolog of Yeast Transcription Factor SNF5

1994 • 523 citations

Functional selectivity of recombinant mammalian SWI/SNF subunits

2000 • 503 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Five SWI genes are required for expression of the HO gene in yeast

1984 • 450 citations

Repression and activation by multiprotein complexes that alter chromatin structure.

1996 • 444 citations

Promoter targeting and chromatin remodeling by the SWI/SNF complex

2000 • 433 citations

Constitutional Mutations of the hSNF5/INI1 Gene Predispose to a Variety of Cancers

1999 • 428 citations

Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

2000 • 413 citations

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

1999 • 394 citations

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

2000 • 394 citations

THE POLYCOMB AND TRITHORAX GROUP PROTEINS OF DROSOPHILA: Trans-Regulators of Homeotic Gene Function

1995 • 390 citations

Recent advances in understanding chromatin remodeling by Swi/Snf complexes

2003 • 348 citations

The Swi/Snf family

2000 • 343 citations

Programming off and on states in chromatin: mechanisms of Polycomb and trithorax group complexes

2002 • 331 citations

An extensive 3′ cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-β family in Drosophila

1991 • 330 citations

Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5

2002 • 320 citations

The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway.

1993 • 320 citations

Spectrum of hSNF5IINI1 Somatic Mutations in Human Cancer and Genotype-Phenotype Correlations

1999 • 308 citations

Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators.

1994 • 306 citations

The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation.

1993 • 299 citations

Disruption of Ini1 Leads to Peri-Implantation Lethality and Tumorigenesis in Mice

2001 • 292 citations

Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes

2001 • 278 citations

Activation Domain–Mediated Targeting of the SWI/SNF Complex to Promoters Stimulates Transcription from Nucleosome Arrays

1999 • 245 citations

Functional interdependence of the yeast SNF2, SNF5, and SNF6 proteins in transcriptional activation.

1991 • 244 citations

mSin3A/Histone Deacetylase 2- and PRMT5-Containing Brg1 Complex Is Involved in Transcriptional Repression of the Myc Target Gene cad

2003 • 236 citations

The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex.

1995 • 225 citations

Cell Cycle Arrest and Repression of Cyclin D1 Transcription by INI1/hSNF5

2002 • 224 citations

When the SWI/SNF complex remodels … the cell cycle

2001 • 196 citations

Genetic Analysis of brahma: The Drosophila Homolog of the Yeast Chromatin Remodeling Factor SWI2/SNF2

1998 • 188 citations

Transcription Activator Interactions with Multiple SWI/SNF Subunits

2002 • 183 citations

Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing

1997 • 178 citations

The Drosophila BRM complex facilitates global transcription by RNA polymerase II

2002 • 168 citations

A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle

2002 • 166 citations

Analysis of the genetic hierarchy guiding wing vein development in Drosophila

1995 • 165 citations

Structural analysis of the yeast SWI/SNF chromatin remodeling complex

2003 • 164 citations

The Neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation

2000 • 161 citations

Leukemic HRX Fusion Proteins Inhibit GADD34-Induced Apoptosis and Associate with the GADD34 and hSNF5/INI1 Proteins

1999 • 159 citations

The in vivo functions of ATP-dependent chromatin-remodelling factors

2002 • 158 citations

Yeast SNF2/SWI2, SNF5, and SNF6 proteins function coordinately with the gene-specific transcriptional activators GAL4 and Bicoid.

1992 • 157 citations

Expression and function of decapentaplegic and thick veins during the differentiation of the veins in the Drosophila wing

1997 • 154 citations

Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes

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Functional analysis of the DNA-stimulated ATPase domain of yeast SWI2/SNF2

1996 • 144 citations

Osa-containing Brahma chromatin remodeling complexes are required for the repression of Wingless target genes

2000 • 141 citations

Chromatin remodeling and Rb activity

2000 • 138 citations

The Drosophila Serum Response Factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered

1996 • 130 citations

Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth

2002 • 130 citations

Genetic analysis of the brahma gene of Drosophila melanogaster and polytene chromosome subdivisions 72AB.

1994 • 126 citations

The trithorax group gene osa encodes an ARID-domain protein that genetically interacts with the Brahma chromatin-remodeling factor to regulate transcription

1999 • 117 citations

Evidence that Swi/Snf directly represses transcription in S. cerevisiae

2002 • 109 citations

Boundaries in the Drosophila wing imaginal disc organize vein-specific genetic programs

1998 • 106 citations

eyelidantagonizes wingless signaling during Drosophiladevelopment and has homology to the Bright family of DNA-binding proteins

1997 • 104 citations

E(z): a polycomb group gene or a trithorax group gene?

1996 • 100 citations

Structure-function analysis of integrase interactor 1/hSNF5L1 reveals differential properties of two repeat motifs present in the highly conserved region

1998 • 89 citations

blistered: a gene required for vein/intervein formation in wings of Drosophila

1994 • 85 citations

Drawing lines in the Drosophila wing: initiation of wing vein development

2000 • 82 citations

Chromatin remodeling enzymes: taming the machines

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Recruitment of chromatin remodeling machines

2000 • 77 citations

Emerging roles for chromatin remodeling in cancer biology

2001 • 74 citations

The role of brahma and related proteins in transcription and development

1995 • 71 citations

Essential Roles of Snf5p in Snf-Swi Chromatin Remodeling In Vivo

2001 • 61 citations

Emerging roles for chromatin remodeling in cancer biology

2001 • 61 citations

SNR1 is an essential subunit in a subset of drosophila brm complexes, targeting specific functions during development

2003 • 56 citations

Chromatin remodeling factor encoded by ini1 induces G1 arrest and apoptosis in ini1-deficient cells

2002 • 56 citations

INI1 expression induces cell cycle arrest and markers of senescence in malignant rhabdoid tumor cells

2003 • 53 citations

Wing vein formation in Drosophila melanogaster: Hairless is involved in the cross-talk between Notch and EGF signaling pathways

2002 • 47 citations

Regulation of Drosophila wing vein patterning: net encodes a bHLH protein repressing rhomboid and is repressed by rhomboid-dependent Egfr signalling

2000 • 42 citations

The Drosophila homeotic gene moira regulates expression of engrailed and HOM genes in imaginal tissues

1997 • 40 citations

The Drosophila SNR1 (SNF5/INI1) Subunit Directs Essential Developmental Functions of the Brahma Chromatin Remodeling Complex

2002 • 38 citations

Selective Gene Regulation by SWI/SNF-Related Chromatin Remodeling Factors

2003 • 31 citations

A Systematic Screen for Dominant Second-Site Modifiers of Merlin/NF2 Phenotypes Reveals an Interaction With blistered/DSRF and scribbler

2001 • 24 citations