Regulation of Drosophila wing vein patterning: net encodes a bHLH protein repressing rhomboid and is repressed by rhomboid-dependent Egfr signalling

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Basic local alignment search tool

1990 • 87,358 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

The Genome of Drosophila Melanogaster

1992 • 3,126 citations

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

Notch Signaling

1995 • 1,282 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing

1996 • 629 citations

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

1994 • 624 citations

A modular misexpression screen in Drosophila detecting tissue-specific phenotypes.

1996 • 564 citations

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

1994 • 560 citations

Structure and function of helix-loop-helix proteins

1994 • 496 citations

The engrailed locus of drosophila: In situ localization of transcripts reveals compartment-specific expression

1985 • 456 citations

Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system.

1994 • 395 citations

rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster.

1990 • 389 citations

In Situ Activation Pattern of Drosophila EGF Receptor Pathway During Development

1997 • 372 citations

Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila

1993 • 359 citations

The white gene as a marker in a new P-element vector for gene transfer inDrosophila

1987 • 355 citations

The WRPW Motif of the Hairy-Related Basic Helix-Loop-Helix Repressor Proteins Acts as a 4-Amino-Acid Transcription Repression and Protein-Protein Interaction Domain

1996 • 344 citations

Evolution and role of Pax genes

1993 • 337 citations

The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway.

1993 • 320 citations

Active repression mechanisms of eukaryotic transcription repressors

1996 • 308 citations

Compartments in the wing of Drosophila: A study of the engrailed gene

1976 • 297 citations

Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues

1998 • 295 citations

Molecular genetics of the achaete-scute gene complex of D. melanogaster

1985 • 287 citations

Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation.

1994 • 252 citations

Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster.

1985 • 251 citations

Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis

1995 • 246 citations

Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed

1997 • 240 citations

BEAUTY: an enhanced BLAST-based search tool that integrates multiple biological information resources into sequence similarity search results.

1995 • 229 citations

Specificity for the Hairy/Enhancer of split Basic Helix-Loop-Helix (bHLH) Proteins Maps outside the bHLH Domain and Suggests Two Separable Modes of Transcriptional Repression

1995 • 223 citations

Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins.

1992 • 220 citations

Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins.

1996 • 218 citations

Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster.

1983 • 213 citations

Choosing a cell fate: a view from the Notch locus

1991 • 213 citations

Choosing a cell fate: a view from the Notch locus

1991 • 196 citations

Repression versus activation in the control of gene transcription

1994 • 187 citations

The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins.

1992 • 179 citations

Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing

1997 • 178 citations

Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development

1996 • 175 citations

Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis

1986 • 171 citations

Analysis of the genetic hierarchy guiding wing vein development in Drosophila

1995 • 165 citations

The Pax2 homolog sparkling is required for development of cone and pigment cells in theDrosophila eye

1997 • 152 citations

The function of engrailed and the specification of Drosophila wing pattern

1995 • 146 citations

Beadex encodes an LMO protein that regulates Apterous LIM–homeodomain activity in Drosophila wing development: a model for LMO oncogene function

1998 • 144 citations

DEVELOPMENTAL GENETICS OF THE VENATION PATTERN OF DROSOPHILA

1992 • 144 citations

rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development

1999 • 139 citations

u-shaped encodes a zinc finger protein that regulates the proneural genesachaete and scute during the formation of bristles in Drosophila

1997 • 139 citations

The Drosophila Serum Response Factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered

1996 • 130 citations

The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing

1997 • 127 citations

Behaviour of cells mutant for an EGFreceptorhomologue ofDrosophilain genetic mosaics

1990 • 110 citations

ventral veinless, the gene encoding the Cf1a transcription factor, links positional information and cell differentiation during embryonic and imaginal development in Drosophila melanogaster

1995 • 106 citations

Boundaries in the Drosophila wing imaginal disc organize vein-specific genetic programs

1998 • 106 citations

hairy mediates dominant repression in the Drosophila embryo

1997 • 103 citations

Molecular, Phenotypic, and Expression Analysis ofvein,a Gene Required for Growth of theDrosophilaWing Disc

1996 • 100 citations

The Drosophila decapentaplegic and short gastrulation genes function antagonistically during adult wing vein development

1996 • 93 citations

Ultrasonic relaxation in the study of rotational isomers

1957 • 92 citations

Genetic analysis of the wing vein pattern of Drosophila

1990 • 88 citations

Three distinct roles for the engrailed gene in Drosophila wing development

1994 • 87 citations

blistered: a gene required for vein/intervein formation in wings of Drosophila

1994 • 85 citations

The knirps and knirps-related genes organize development of the second wing vein in Drosophila

1998 • 80 citations

A network of interacting transcriptional regulators involved in Drosophila neural fate specification revealed by the yeast two-hybrid system

1997 • 78 citations

Genetic interactions and cell behaviour in blistered mutants during proliferation and differentiation of the Drosophila wing

1998 • 66 citations

Inductive mechanisms in the process of wing vein formation inDrosophila

1977 • 62 citations

Cloning of the extra sex combs gene of Drosophila and its identification by P-element-mediated gene transfer

1985 • 54 citations

Down-regulation of Drosophila Egf-r mRNA levels following hyperactivated receptor signaling

1994 • 46 citations

Control of EGF receptor activation in Drosophila

1997 • 45 citations

Differential requirement for EGF-like ligands in Drosophila wing development

1997 • 41 citations

Localized activation of RTK/MAPK pathways during Drosophila development

1998 • 39 citations

Built by association: structure and function of helix-loop-helix DNA-binding proteins

1994 • 39 citations

New functions of the Drosophila rhomboid gene during embryonic and adult development are revealed by a novel genetic method, enhancer piracy

1994 • 34 citations

Growth and patterning from the engrailed interface.

1998 • 25 citations

Repression of the wing vein development in Drosophila by the nuclear matrix protein Plexus

1999 • 23 citations

Neurogenesis in Drosophila: an historical perspective and some prospects.

1997 • 22 citations

The use of S-2-cyanoethyl phosphorothioate In the preparation of ollgo 5′-deoxy-5′-thlothymldylates

1975 • 20 citations

Wing surface interactions in venation patterning in Drosophila

1997 • 11 citations

A simple procedure for assigning a sequence motif with an obscure pattern: application to the basic/helix-loop-helix motif

1994 • 6 citations

Deleted Work

1955 • 0 citations