Back to search

Pilot study of recombinant human soluble tumor necrosis factor (TNF) receptor (p75) fusion protein (TNFR:Fc; Enbrel) in patients with refractory multiple myeloma: increase in plasma TNFα levels during treatment

Data up to Jan 2025

Published2003
Citations63
References34

Total Citations Per Year

Abstract

References (34)

A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

1975 • 3,051 citations

Antitumor Activity of Thalidomide in Refractory Multiple Myeloma

1999 • 2,565 citations

Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

1997 • 1,651 citations

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors

1986 • 1,433 citations

Etanercept Therapy in Rheumatoid Arthritis

1999 • 1,407 citations

Anti-TNFα Therapy of Rheumatoid Arthritis: What Have We Learned?

2001 • 1,237 citations

Treatment of Septic Shock with the Tumor Necrosis Factor Receptor:Fc Fusion Protein

1996 • 1,217 citations

An interleukin 1 like factor stimulates bone resorption in vitro

1983 • 1,017 citations

A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins

1990 • 977 citations

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

1990 • 918 citations

Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists.

1993 • 837 citations

Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome

1995 • 805 citations

Multiple Myeloma: Increasing Evidence for a Multistep Transformation Process

1998 • 761 citations

Effective Treatment of Advanced Multiple Myeloma Refractory to Alkylating Agents

1984 • 667 citations

Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients

2001 • 553 citations

Safety and Efficacy of a Soluble P75 Tumor Necrosis Factor Receptor (Enbrel, Etanercept) in Patients With Advanced Heart Failure

1999 • 397 citations

Results of Targeted Anti–Tumor Necrosis Factor Therapy With Etanercept (ENBREL) in Patients With Advanced Heart Failure

2001 • 386 citations

[Etanercept for therapy of rheumatoid arthritis].

2005 • 344 citations

Etanercept combined with conventional treatment in Wegener's granulomatosis: A six-month open-label trial to evaluate safety

2001 • 220 citations

Production of cytokines by bone marrow cells obtained from patients with multiple myeloma

1989 • 156 citations

Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group

1995 • 153 citations

Tumor necrosis factor is a survival and proliferation factor for human myeloma cells.

1999 • 100 citations

Differential mobilization of myeloma cells and normal hematopoietic stem cells in multiple myeloma after treatment with cyclophosphamide and granulocyte-macrophage colony-stimulating factor

1996 • 85 citations

Etanercept in rheumatoid arthritis

2001 • 82 citations

TNF and IL‐6 are potent growth factors for OH‐2, a novel human myeloma cell line

1994 • 80 citations

Etanercept (Enbrel): update on therapeutic use

2000 • 72 citations

Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors.

1996 • 47 citations

Etanercept and urticaria in patients with juvenile idiopathic arthritis.

2000 • 46 citations

EVALUATION OF RECOMBINANT HUMAN SOLUBLE DIMERIC TUMOR NECROSIS FACTOR RECEPTOR FOR PREVENTION OF OKT3-ASSOCIATED ACUTE CLINICAL SYNDROME1,2

1996 • 45 citations

Autocrine Growth by Two Cytokines, Interleukin-6 and Tumor Necrosis Factor Alpha, in the Myeloma Cell Line KHM-1A

1990 • 31 citations

THE ROLE OF THE TWO TNF RECEPTORS IN PROLIFERATION, NF-κB ACTIVATION AND DISCRIMINATION BETWEEN TNF AND LTαSIGNALLING IN THE HUMAN MYELOMA CELL LINE OH-2

1996 • 27 citations

New insights in the clinical biology of multiple myeloma.

1997 • 17 citations

Multiple myeloma and other differentiated B-cell disorders.

1994 • 6 citations

Refractory multiple myeloma: recent advances in therapy.

1995 • 5 citations

Cited By (0)

Loading...
Pilot study of recombinant human soluble tumor necrosis factor (TNF) receptor (p75)… (2003) – Leukemia Research | Metascience Observatory Explorer