A murine homolog of the yeast RNA1 gene is required for postimplantation development.

PCR protocols — A guide to methods and applications

1990 • 12,897 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Structural features in eukaryotic mRNAs that modulate the initiation of translation.

1991 • 1,849 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.

1991 • 1,358 citations

FUNCTION AND REGULATION OF RAS

1993 • 1,161 citations

Cloning of the T gene required in mesoderm formation in the mouse

1990 • 847 citations

Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line.

1992 • 729 citations

The House Mouse: Atlas of Embryonic Development

1972 • 689 citations

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo

1993 • 680 citations

Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus

1982 • 611 citations

Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation

1993 • 606 citations

The House Mouse

1989 • 559 citations

Mouse Embryonic Stem Cells and Reporter Constructs to Detect Developmentally Regulated Genes

1989 • 491 citations

Development and applications of a molecular genetic linkage map of the mouse genome

1991 • 427 citations

Catalog Of Mutant Genes And Polymorphic Loci

1996 • 404 citations

A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.

1992 • 281 citations

Linkage, recombination and mapping

1981 • 279 citations

A yeast mutant which accumulates precursor tRNAs

1978 • 231 citations

The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus.

1990 • 228 citations

THE MOLECULAR AND CELLULAR BASIS OF PREIMPLANTATION MOUSE DEVELOPMENT

1981 • 183 citations

Clonal Analysis of Cell Fate During Gastrulation and Early Neurulation in the Mouse

2007 • 172 citations

The embryonic lethality of homozygous lethal yellow mice (Ay/Ay) is associated with the disruption of a novel RNA-binding protein.

1993 • 171 citations

Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure.

1992 • 142 citations

Evidence for expression of the paternal genome in the two-cell mouse embryo

1981 • 139 citations

DNA Methylation and Development

2015 • 135 citations

A fast and simple procedure for sequencing double stranded DNA with Sequenase

1991 • 98 citations

A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif.

1993 • 93 citations

Selective disruption of genes expressed in totipotent embryonal stem cells.

1992 • 92 citations

Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine Hβ58 embryonic lethal transgene insertion

1992 • 88 citations

Identification of cellular promoters by using a retrovirus promoter trap

1989 • 74 citations

Analysis of yeast prp20 mutations and functional complementation by the human homologue RCC1, a protein involved in the control of chromosome condensation

1991 • 67 citations

Structural and functional analyses of Saccharomyces cerevisiae wild-type and mutant RNA1 genes.

1989 • 65 citations

Retrovirus promoter-trap vector to induce lacZ gene fusions in mammalian cells

1991 • 57 citations

Characterization of an essential Saccharomyces cerevisiae gene related to RNA processing: cloning of RNA1 and generation of a new allele with a novel phenotype.

1985 • 48 citations

Fluorescence-activated sorting of totipotent embryonic stem cells expressing developmentally regulated lacZ fusion genes.

1992 • 48 citations

Molecular analysis of the Mov 34 mutation: transcript disrupted by proviral integration in mice is conserved in Drosophila

1990 • 42 citations

SRN1, a yeast gene involved in RNA processing, is identical to HEX2/REG1, a negative regulator in glucose repression.

1992 • 41 citations

Enrichment of Insertional Mutants Following Retrovirus Gene Trap Selection

1993 • 35 citations

An interspecific linkage map of mouse chromosome 15 positioned with respect to the centromere

1992 • 33 citations

Expression of Pax-3- and neuroectoderm-inducing activities during differentiation of P19 embryonal carcinoma cells

1992 • 24 citations

A suppressor of temperature-sensitive rna mutations that affect mRNA metabolism in Saccharomyces cerevisiae.

1982 • 23 citations

Blind—A Dominant Mutation in Mice

1968 • 14 citations

Developmental studies of the lethal gene Bld in the mouse. I. Post-implantation development of the lethal homozygote.

1979 • 8 citations

The yeast RNA1 protein, necessary for RNA processing, is homologous to the human ribonuclease/angiogenin inhibitor (RAI)

1992 • 6 citations