Human inhibitory and activating Ig-like receptors which modulate the function of myeloid cells

The Nature of the Principal Type 1 Interferon-Producing Cells in Human Blood

1999 • 2,255 citations

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

1999 • 1,754 citations

NK CELL RECEPTORS

1998 • 1,666 citations

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 • 998 citations

A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells

1997 • 933 citations

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

1998 • 892 citations

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis

1998 • 706 citations

A Novel Immunoglobulin Superfamily Receptor for Cellular and Viral MHC Class I Molecules

1997 • 681 citations

A family of proteins that inhibit signalling through tyrosine kinase receptors

1997 • 648 citations

Molecular Cloning of NKp46: A Novel Member of the Immunoglobulin Superfamily Involved in Triggering of Natural Cytotoxicity

1998 • 562 citations

Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules.

1998 • 498 citations

The Ly-49 and NKR-P1 Gene Families Encoding Lectin-Like Receptors on Natural Killer Cells: The NK Gene Complex

1993 • 465 citations

Cutting Edge: Human Myelomonocytic Cells Express an Inhibitory Receptor for Classical and Nonclassical MHC Class I Molecules

1998 • 430 citations

A Novel Inhibitory Receptor (ILT3) Expressed on Monocytes, Macrophages, and Dendritic Cells Involved in Antigen Processing

1997 • 426 citations

Costimulatory regulation of T cell function

1999 • 391 citations

The CD1 Family: A Third Lineage of Antigen-Presenting Molecules

1995 • 389 citations

LAIR-1, a Novel Inhibitory Receptor Expressed on Human Mononuclear Leukocytes

1997 • 386 citations

The Inhibitory Receptor LIR-1 Uses a Common Binding Interaction to Recognize Class I MHC Molecules and the Viral Homolog UL18

1999 • 357 citations

The ILT2(LIR1) and CD94/NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells

1999 • 355 citations

Integrin-associated Protein Is a Ligand for the P84 Neural Adhesion Molecule

1999 • 347 citations

A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

1997 • 327 citations

A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells

1997 • 325 citations

Natural killer cell receptors

1995 • 314 citations

Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: Structural evidence for new stimulatory and inhibitory pathways

1997 • 298 citations

Signal Transduction during Natural Killer Cell Activation: Inside the Mind of a Killer

1997 • 293 citations

Human Signal-Regulatory Protein Is Expressed on Normal, But Not on Subsets of Leukemic Myeloid Cells and Mediates Cellular Adhesion Involving Its Counterreceptor CD47

1999 • 285 citations

Expression cloning of a human Fc receptor for IgA.

1990 • 259 citations

Tetrameric Complexes of Human Histocompatibility Leukocyte Antigen (HLA)-G Bind to Peripheral Blood Myelomonocytic Cells

1999 • 252 citations

Signal-Regulatory Protein Is Selectively Expressed by Myeloid and Neuronal Cells

1998 • 248 citations

High Expression of Inhibitory Receptor SHPS-1 and Its Association with Protein-tyrosine Phosphatase SHP-1 in Macrophages

1998 • 233 citations

Organization of the leukocyte receptor cluster (LRC) on human Chromosome 19q13.4

1999 • 225 citations

Killer cell inhibitory receptors: diversity, specificity, and function

1997 • 223 citations

Regulation of Early Events in Integrin Signaling by Protein Tyrosine Phosphatase SHP-2

1999 • 219 citations

DAP12-mediated Signal Transduction in Natural Killer Cells

1998 • 212 citations

The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1

1998 • 208 citations

Requirement of SH2-containing Protein Tyrosine Phosphatases SHP-1 and SHP-2 for Paired Immunoglobulin-like Receptor B (PIR-B)–mediated Inhibitory Signal

1998 • 205 citations

Identification of Major Binding Proteins and Substrates for the SH2-Containing Protein Tyrosine Phosphatase SHP-1 in Macrophages

1998 • 201 citations

The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes

1998 • 198 citations

A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors

1997 • 183 citations

A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells

1999 • 182 citations

Molecular Cloning of a Novel Murine Cell-surface Glycoprotein Homologous to Killer Cell Inhibitory Receptors

1997 • 173 citations

Human myeloid cells express an activating ILT receptor (ILT1) that associates with Fc receptor gamma-chain.

1999 • 172 citations

Cutting Edge: Signal-Regulatory Protein β1 Is a DAP12-Associated Activating Receptor Expressed in Myeloid Cells

2000 • 161 citations

A Gene Outside the Human MHC Related to Classical HLA Class I Genes

1995 • 161 citations

Biochemical Nature and Cellular Distribution of the Paired Immunoglobulin-like Receptors, PIR-A and PIR-B

1999 • 152 citations

Cutting Edge: Human Myeloid Cells Express an Activating ILT Receptor (ILT1) That Associates with Fc Receptor γ-Chain

1999 • 145 citations

Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1

1999 • 140 citations

Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor.

1997 • 137 citations

The Tyrosine Phosphatase PTP1C Associates with Vav, Grb2, and mSos1 in Hematopoietic Cells

1996 • 124 citations

Roles of the Complex Formation of SHPS-1 with SHP-2 in Insulin-stimulated Mitogen-activated Protein Kinase Activation

1998 • 116 citations

Mouse natural killer cells express gp49B1, a structural homologue of human killer inhibitory receptors.

1997 • 116 citations

Cutting Edge: KAP10, a Novel Transmembrane Adapter Protein Genetically Linked to DAP12 but with Unique Signaling Properties

1999 • 115 citations

Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49.

1994 • 114 citations

The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1+ NK cell clones

1999 • 113 citations

Transduction of cytotoxic signals in natural killer cells: a general model of fine tuning between activatory and inhibitory pathways in lymphocytes

1997 • 107 citations

Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells

1997 • 104 citations

Isotypic variation of novel immunoglobulin-like transcript/killer cell inhibitory receptor loci in the leukocyte receptor complex

1998 • 99 citations

Paired Immunoglobulin-like Receptor (PIR)-A Is Involved in Activating Mast Cells through Its Association with Fc Receptor γ Chain

1998 • 99 citations

Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells.

1997 • 90 citations

Plasmacytoid T cells: A cell population normally present in the reactive lymph node

1988 • 82 citations

Molecular cloning of gp49, a cell-surface antigen that is preferentially expressed by mouse mast cell progenitors and is a new member of the immunoglobulin superfamily

1991 • 79 citations

Inhibitory and Stimulatory Functions of Paired Ig-Like Receptor (PIR) Family in RBL-2H3 Cells

1998 • 78 citations

The MIC gene family

1996 • 76 citations

Inhibitory and activating receptors involved in immune surveillance by human NK and myeloid cells

1999 • 65 citations

Paired Immunoglobulin-like Receptors of Activating and Inhibitory Types

1999 • 38 citations

A Novel Family of Inhibitory Receptors for HLA Class I Molecules That Modulate Function of Lymphoid and Myeloid Cells

1999 • 23 citations