The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

NITRIC OXIDE AND MACROPHAGE FUNCTION

1997 • 4,106 citations

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

A Class I Antigen, HLA-G, Expressed in Human Trophoblasts

1990 • 1,417 citations

Implantation and the placenta: key pieces of the development puzzle

1994 • 1,362 citations

Fc Receptors

1991 • 1,220 citations

F<scp>c</scp>RECEPTOR BIOLOGY

1997 • 1,219 citations

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 • 998 citations

A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells

1997 • 933 citations

RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

1996 • 871 citations

Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FeγRIIB

1996 • 770 citations

A Novel Immunoglobulin Superfamily Receptor for Cellular and Viral MHC Class I Molecules

1997 • 681 citations

Recruitment of Tyrosine Phosphatase HCP by the Killer Cell Inhibitory Receptor

1996 • 625 citations

Recruitment and Activation of PTP1C in Negative Regulation of Antigen Receptor Signaling by FcγRIIB1

1995 • 535 citations

Deletion of SHIP or SHP-1 Reveals Two Distinct Pathways for Inhibitory Signaling

1997 • 505 citations

The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation

1995 • 448 citations

Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.

1993 • 395 citations

Fc receptors: Rubor redux

1994 • 361 citations

Major histocompatibility complex class I‐specific receptors on human natural killer and T lymphocytes

1997 • 360 citations

Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors.

1995 • 359 citations

Sequential Involvement of Lck and SHP-1 with MHC-Recognizing Receptors on NK Cells Inhibits FcR-Initiated Tyrosine Kinase Activation

1996 • 341 citations

Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation.

1996 • 332 citations

The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cells

1997 • 327 citations

A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

1997 • 327 citations

Dendritic cells capable of stimulating T cells in germinal centres

1996 • 309 citations

Production of human cells expressing individual transferred HLA-A,-B,-C genes using an HLA-A,-B,-C null human cell line.

1989 • 305 citations

Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: Structural evidence for new stimulatory and inhibitory pathways

1997 • 298 citations

A macrophage Fcγ receptor and the mast cell receptor for IgE share an identical subunit

1989 • 268 citations

Characterization and expression of the gene for the human Fc receptor gamma subunit. Definition of a new gene family.

1990 • 225 citations

Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C.

1996 • 213 citations

Functional Association between the Human Myeloid Immunoglobulin A Fc Receptor (CD89) and FcR γChain

1995 • 205 citations

Biological activity of human-mouse IgG1, IgG2, IgG3, and IgG4 chimeric monoclonal antibodies with antitumor specificity.

1988 • 202 citations

Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase.

1993 • 198 citations

Fc-dependent inhibition of mouse B cell activation by whole anti-mu antibodies.

1983 • 187 citations

A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors

1997 • 183 citations

Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.

1993 • 178 citations

Association of the high-affinity receptor for IgG (Fc gamma RI) with the gamma subunit of the IgE receptor.

1993 • 176 citations

The Emerging Field of Receptor-Mediated Inhibitory Signaling: SHP or SHIP?

1996 • 174 citations

Mechanisms for Regulating Expression of Membrane Isoforms of FcγRIII (CD16)

1989 • 162 citations

Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/activatory counterparts.

1997 • 161 citations

Phenotypical and functional characterization of Fey receptor I (CD64)‐negative monocytes, a minor human monocyte subpopulation with high accessory and antiviral activity

1993 • 152 citations

Characterization of expression, cytokine regulation, and effector function of the high affinity IgG receptor Fc gamma RI (CD64) expressed on human blood dendritic cells.

1997 • 150 citations

Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn.

1994 • 148 citations

Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells.

1992 • 145 citations

Fc gamma RI and Fc gamma RII on monocytes and granulocytes are cytotoxic trigger molecules for tumor cells.

1987 • 140 citations

Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor.

1997 • 137 citations

Involvement of p72syk, a protein-tyrosine kinase, in Fc gamma receptor signaling

1993 • 137 citations

Cross-linking of both Fc gamma RI and Fc gamma RII induces secretion of tumor necrosis factor by human monocytes, requiring high affinity Fc-Fc gamma R interactions. Functional activation of Fc gamma RII by treatment with proteases or neuraminidase.

1990 • 136 citations

Phagocytosis of tumor cells by human monocytes cultured in recombinant macrophage colony-stimulating factor.

1990 • 127 citations

Identification of the Major Tyrosine Kinase Substrate in Signaling Complexes Formed after Engagement of Fcγ Receptors

1995 • 117 citations

Induction of phagocytosis by a protein tyrosine kinase

1995 • 106 citations

Clustering of the high affinity Fc receptor for immunoglobulin G (Fc gamma RI) results in phosphorylation of its associated gamma-chain.

1994 • 93 citations

Stimulation of tyrosine phosphorylation and calcium mobilization by Fc gamma receptor cross-linking. Regulation by the phosphotyrosine phosphatase CD45.

1993 • 92 citations

What Goes Up Must Come Down: The Emerging Spectrum of Inhibitory Receptors

1997 • 79 citations

Monocyte Fc gamma receptor cross-linking induces IL-8 production.

1995 • 76 citations

Protein tyrosine phosphorylation induced via the IgG receptors Fc gamma Ri and Fc gamma RII in the human monocytic cell line THP-1.

1992 • 75 citations

Flow cytometric analysis of murine splenic B lymphocyte cytosolic free calcium response to anti‐IgM and anti‐IgD

1987 • 62 citations

Cross‐linking of Both Types of IgG Fc Receptors, FcγyRI and FcγyRII, Enhances Intracellular Free Ca²⁺ in the Monocytic Cell Line U937

1990 • 58 citations

Human leukocytes kill varicella-zoster virus-infected fibroblasts in the presence of murine monoclonal antibodies to virus-specific glycoproteins

1985 • 40 citations

Antibody-dependent cellular cytotoxicity against HIV-coated target cells by peripheral blood monocytes from HIV seropositive asymptomatic patients.

1990 • 34 citations

Human B cells express two types of interleukin-1 receptors

1990 • 30 citations