Gene Polymorphisms of Homocysteine Metabolism-Related Enzymes in Chinese Patients with Occlusive Coronary Artery or Cerebral Vascular Diseases

Homocysteine and Atherothrombosis

1998 • 2,021 citations

Common Methylenetetrahydrofolate Reductase Gene Mutation Leads to Hyperhomocysteinemia but Not to Vascular Disease

1998 • 672 citations

Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.

1996 • 670 citations

Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.

1991 • 615 citations

Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase.

1988 • 607 citations

Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders

1996 • 399 citations

Hyperhomocysteinemia, Atherosclerosis and Thrombosis

1999 • 364 citations

The Mutation Ala677→Val in the Methylene Tetrahydrofolate Reductase Gene: A Risk Factor for Arterial Disease and Venous Thrombosis

1997 • 313 citations

Genetic Polymorphism of 5,10-Methylenetetrahydrofolate Reductase (MTHFR) as a Risk Factor for Coronary Artery Disease

1997 • 264 citations

Thermolabile Methylenetetrahydrofolate Reductase in Coronary Artery Disease

1997 • 230 citations

Common Mutation in Methylenetetrahydrofolate Reductase

1996 • 226 citations

Human Methionine Synthase

1997 • 181 citations

High prevalence of a mutation in the cystathionine beta-synthase gene.

1996 • 171 citations

Methylenetetrahydrofolate Reductase Gene and Coronary Artery Disease

1997 • 169 citations

The molecular basis of homocystinuria due to cystathionine beta-synthase deficiency in Italian families, and report of four novel mutations.

1995 • 162 citations

Analysis of the 677 C→T Mutation of the Methylenetetrahydrofolate Reductase Gene in Different Ethnic Groups

1998 • 158 citations

Polygenic influence on plasma homocysteine: association of two prevalent mutations, the 844ins68 of cystathionine β-synthase and A2756G of methionine synthase, with lowered plasma homocysteine levels

2000 • 148 citations

Genetic Polymorphism of Methylenetetrahydrofolate Reductase and Myocardial Infarction

1996 • 145 citations

Cloning, mapping and RNA analysis of the human methionine synthase gene

1996 • 144 citations

Defects in human methionine synthase in cblG patients

1996 • 115 citations

Genetic causes of mild hyperhomocysteinemia in patients with premature occlusive coronary artery diseases

1999 • 113 citations

Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population

1999 • 91 citations

Relationship Between Homocysteine and Thrombotic Disease

1998 • 69 citations

Thermolabile Methylenetetrahydrofolate Reductase

1997 • 24 citations