The immunomodulator FTY720 is phosphorylated and released from platelets

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

2004 • 2,462 citations

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

2002 • 1,655 citations

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

2002 • 1,478 citations

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

2005 • 681 citations

Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform

2000 • 654 citations

FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. I. FTY720 Selectively Decreases the Number of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing

1998 • 586 citations

Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase

1998 • 528 citations

Structural and functional characteristics of S1P receptors

2004 • 450 citations

Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum

1997 • 442 citations

Expression of the Sphingosine 1-Phosphate Receptor, S1P1, on T-cells Controls Thymic Emigration

2004 • 436 citations

Phosphorylation of the Immunomodulatory Drug FTY720 by Sphingosine Kinases

2003 • 427 citations

Role of ABCC1 in export of sphingosine-1-phosphate from mast cells

2006 • 406 citations

Erythrocytes store and release sphingosine 1‐phosphate in blood

2007 • 355 citations

Extracellular Export of Sphingosine Kinase-1 Enzyme

2002 • 281 citations

Sphingosine Kinase 2 Is Required for Modulation of Lymphocyte Traffic by FTY720

2005 • 211 citations

Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells

2000 • 210 citations

Sphingosine 1-Phosphate Induces Platelet Activation through an Extracellular Action and Shares a Platelet Surface Receptor with Lysophosphatidic Acid

1997 • 200 citations

Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes

2007 • 182 citations

Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate

2007 • 170 citations

Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner

2005 • 157 citations

Simultaneous Quantitative Analysis of Sphingoid Base 1-Phosphates in Biological Samples by o-Phthalaldehyde Precolumn Derivatization after Dephosphorylation with Alkaline Phosphatase

2002 • 149 citations

Metabolism and functional effects of sphingolipids in blood cells

1999 • 116 citations

FTY720 (fingolimod) in renal transplantation

2006 • 102 citations

マスト細胞からのスフィンゴシン‐1‐りん酸の運び出しに果たすABCC1の役割

2006 • 95 citations

Metabolism and functional effects of sphingolipids in blood cells

1999 • 90 citations

Sphingosine-1-phosphate Lyase Is Involved in the Differentiation of F9 Embryonal Carcinoma Cells to Primitive Endoderm

2003 • 75 citations