Sphingosine-1-phosphate Lyase Is Involved in the Differentiation of F9 Embryonal Carcinoma Cells to Primitive Endoderm

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1996 • 1,493 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

1993 • 879 citations

Hormonal induction of differentiation in teratocarcinoma stem cells: Generation of parietal endoderm by retinoic acid and dibutyryl cAMP

1980 • 803 citations

Sphingosine 1-phosphate signalling in mammalian cells

2000 • 698 citations

Sphingosine Kinase Expression Increases Intracellular Sphingosine-1-Phosphate and Promotes Cell Growth and Survival

1999 • 516 citations

Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival

1998 • 468 citations

Sphingosine 1-phosphate signalling in mammalian cells

2000 • 458 citations

Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum

1997 • 442 citations

Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway

1998 • 404 citations

Calcium mobilization via sphingosine kinase in signalling by the FcɛRI antigen receptor

1996 • 374 citations

The novel mechanism of initiation of picornavirus RNA translation

1990 • 368 citations

Involvement of Sphingosine 1-Phosphate in Nerve Growth Factor-Mediated Neuronal Survival and Differentiation

1997 • 278 citations

Sphingosine‐1‐phosphate: signaling inside and out

2000 • 275 citations

Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway.

1994 • 273 citations

Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities

1989 • 259 citations

The BST1 Gene of Saccharomyces cerevisiaeIs the Sphingosine-1-phosphate Lyase

1997 • 235 citations

Purification and Characterization of Rat Kidney Sphingosine Kinase

1998 • 221 citations

Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors

1998 • 208 citations

Functions of a new family of sphingosine-1-phosphate receptors

2000 • 194 citations

Molecular Cloning of Differentially Expressed Genes in Human Epithelial Ovarian Cancer

1994 • 183 citations

FcγRI Coupling to Phospholipase D Initiates Sphingosine Kinase-mediated Calcium Mobilization and Vesicular Trafficking

1998 • 172 citations

Identification of the First Mammalian Sphingosine Phosphate Lyase Gene and Its Functional Expression in Yeast

1998 • 168 citations

N,N-Dimethylsphingosine Inhibition of Sphingosine Kinase and Sphingosine 1-Phosphate Activity in Human Platelets

1996 • 162 citations

Molecular cloning of complementary DNA to mouse tissue plasminogen activator mRNA and its expression during F9 teratocarcinoma cell differentiation.

1988 • 156 citations

Simultaneous Quantitative Analysis of Sphingoid Base 1-Phosphates in Biological Samples by o-Phthalaldehyde Precolumn Derivatization after Dephosphorylation with Alkaline Phosphatase

2002 • 149 citations

Sphingosine 1-phosphate receptors

2001 • 139 citations

Functional Roles of Sphingosine, Sphingosine 1-Phosphate, and Methylsphingosines: In Regard to Membrane Sphingolipid Signaling Pathways

1997 • 134 citations

Analysis of Phosphorylated Sphingolipid Long-Chain Bases Reveals Potential Roles in Heat Stress and Growth Control in Saccharomyces

1999 • 133 citations

Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2

1998 • 119 citations

Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q2211DNA sequence was deposited in the EMBL database (AJ011304).

2000 • 108 citations

Expression of the cytokeratin endo A gene during early mouse embryogenesis.

1985 • 108 citations

Regulation of Rat DOC-2 Gene during Castration-Induced Rat Ventral Prostate Degeneration and Its Growth Inhibitory Function in Human Prostatic Carcinoma Cells*

1998 • 99 citations

[28] Sphingosine-1-phosphate lyase

2000 • 97 citations

Regulatory Effect of Phorbol Esters on Sphingosine Kinase in BALB/C 3T3 Fibroblasts (Variant A31): Demonstration of Cell Type-Specific Response - A Preliminary Note

1994 • 87 citations

Molecular basis for resistance to the anticancer drug cisplatin in Dictyostelium The GenBank accession numbers for the sequences reported in this paper are AF233610 (S-1-P lyase), AF233612 (PIP5K), AF233611 (P2Y purine receptor 1), AF233613 (CAAX prenyl protease) and AF233614 (unidentified gene).

2000 • 82 citations

TheDPL1Gene Is Involved in Mediating the Response to Nutrient Deprivation inSaccharomyces cerevisiae

1999 • 70 citations

Sphingosine-1-phosphate lyase has a central role in the development of Dictyostelium discoideum

2001 • 67 citations

Cell Type-specific Localization of Sphingosine Kinase 1a in Human Tissues

2001 • 58 citations

The Ras/Erk Pathway Induces Primitive Endoderm but Prevents Parietal Endoderm Differentiation of F9 Embryonal Carcinoma Cells

1999 • 54 citations

Disabled-2 Mediates c-Fos Suppression and the Cell Growth Regulatory Activity of Retinoic Acid in Embryonic Carcinoma Cells

2001 • 38 citations

Differential Expression of Mouse Disabled 2 Gene in Retinoic Acid-treated F9 Embryonal Carcinoma Cells and Early Mouse Embryos

1999 • 27 citations

p67 isoform of mouse disabled 2 protein acts as a transcriptional activator during the differentiation of F9 cells

2000 • 26 citations

Differentiation of F9 Teratocarcinoma Stem Cells to Primitive Endoderm Is Regulated by the Giα2/Gsα Axis via Phospholipase C and Not Adenylylcyclase

1996 • 17 citations

A Putative G-Protein-Coupled Receptor, H218, Is Down-regulated during the Retinoic Acid-Induced Differentiation of F9 Embryonal Carcinoma Cells

1998 • 13 citations

Increased expression of c-jun, but not retinoic acid receptor β, is associated with F9 teratocarcinoma stem cell differentiation induced by polyamine depletion

1997 • 8 citations