Gene transfer of nitric oxide synthase

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Asymmetric Dimethylarginine (ADMA): A Novel Risk Factor for Endothelial Dysfunction

1998 • 1,182 citations

Constitutive Expression of phVEGF ₁₆₅ After Intramuscular Gene Transfer Promotes Collateral Vessel Development in Patients With Critical Limb Ischemia

1998 • 1,109 citations

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells.

1993 • 1,079 citations

Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene.

1995 • 783 citations

Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase.

1992 • 712 citations

Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit.

1992 • 697 citations

Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator.

1991 • 529 citations

Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits.

1994 • 501 citations

A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo.

1995 • 490 citations

Nitric Oxide Modulates the Expression of Monocyte Chemoattractant Protein 1 in Cultured Human Endothelial Cells

1995 • 475 citations

Gene therapy inhibiting neointimal vascular lesion

1995 • 387 citations

Fluid shear stress induces endothelial transforming growth factor beta-1 transcription and production. Modulation by potassium channel blockade.

1995 • 356 citations

Nitric oxide and prostacyclin. Divergence of inhibitory effects on monocyte chemotaxis and adhesion to endothelium in vitro.

1991 • 331 citations

Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine.

1994 • 330 citations

Elevatedl-Arginine/Dimethylarginine Ratio Contributes to Enhanced Systemic NO Production by Dietaryl-Arginine in Hypercholesterolemic Rabbits

1996 • 308 citations

Fluid Flow Inhibits Endothelial Adhesiveness

1996 • 300 citations

Shear Stress Modulates Expression of Cu/Zn Superoxide Dismutase in Human Aortic Endothelial Cells

1996 • 294 citations

Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease

1998 • 273 citations

Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta. PGH2 does not contribute to impaired endothelium-dependent relaxation.

1994 • 255 citations

Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production

1995 • 251 citations

Dietary <scp>l</scp> -Arginine Reduces the Progression of Atherosclerosis in Cholesterol-Fed Rabbits

1997 • 251 citations

Inhibition of Endothelial Vascular Cell Adhesion Molecule-1 Expression by Nitric Oxide Involves the Induction and Nuclear Translocation of IκBα

1997 • 250 citations

Asymmetrical Dimethylarginine, an Endogenous Nitric Oxide Synthase Inhibitor, in Experimental Hypertension

1997 • 238 citations

Nitric Oxide Regulates Monocyte Chemotactic Protein-1

1997 • 221 citations

Exposure to Shear Stress Alters Endothelial Adhesiveness

1995 • 181 citations

<scp>l</scp> -Arginine Prevents Xanthoma Development and Inhibits Atherosclerosis in LDL Receptor Knockout Mice

1997 • 159 citations

Endothelial Gene Regulation by Laminar Shear Stress

1997 • 111 citations

Effect of local intra-arterial asymmetric dimethylarginine (ADMA) on the forearm arteriolar bed of healthy volunteers.

1993 • 104 citations

Arginine: A New Therapy for Atherosclerosis?

1997 • 85 citations

In Vivo Gene Transfer of Nitric Oxide Synthase Enhances Vasomotor Function in Carotid Arteries From Normal and Cholesterol-Fed Rabbits

1998 • 84 citations

Accelerated Endothelialization by Local Delivery of Recombinant Human Vascular Endothelial Growth Factor Reduces In-Stent Intimal Formation

1997 • 82 citations

Superoxide anion production by rabbit thoracic aorta: effect of endothelium-derived nitric oxide

1993 • 77 citations