PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage

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1999 • 3,923 citations

Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator

2003 • 1,964 citations

Peroxisome proliferator–activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis

2000 • 1,228 citations

Mitochondrial Biogenesis in Mammals: The Role of Endogenous Nitric Oxide

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Molecular and Cellular Basis of Cardiovascular Gender Differences

2005 • 1,044 citations

Nuclear activators and coactivators in mammalian mitochondrial biogenesis

2002 • 611 citations

Mitochondrial localization of estrogen receptor β

2004 • 486 citations

Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells

2002 • 339 citations

Nuclear Receptor Minireview Series

2001 • 308 citations

Estradiol protects against ATP depletion, mitochondrial membrane potential decline and the generation of reactive oxygen species induced by 3‐nitroproprionic acid in SK‐N‐SH human neuroblastoma cells

2001 • 203 citations

SEX DIFFERENCES IN THE MYOCARDIAL INFLAMMATORY RESPONSE TO ACUTE INJURY

2004 • 179 citations

Hypertonic saline resuscitation: a tool to modulate immune function in trauma patients?

1997 • 179 citations

Effect of estrogen on global myocardial ischemia-reperfusion injury in female rats

2000 • 179 citations

HYPERTONIC SALINE RESUSCITATION

1997 • 157 citations

Cellular mechanisms in shock and ischemia and their correction

1983 • 153 citations

Estradiol Administration After Trauma-Hemorrhage Improves Cardiovascular and Hepatocellular Functions in Male Animals

2000 • 152 citations

Hemorrhage Activates Myocardial NFκB and Increases TNF-α in the Heart

1997 • 136 citations

The female reproductive cycle is an important variable in the response to trauma-hemorrhage

2000 • 136 citations

Flutamide: a novel agent for restoring the depressed cell-mediated immunity following soft-tissue trauma and hemorrhagic shock.

1997 • 129 citations

Testosterone receptor blockade after trauma-hemorrhage improves cardiac and hepatic functions in males

1997 • 113 citations

Mechanism of cardiac depression after trauma-hemorrhage: increased cardiomyocyte IL-6 and effect of sex steroids on IL-6 regulation and cardiac function

2004 • 105 citations

FLUTAMIDE

1997 • 100 citations

Recovery of hepatocellular ATP and “pericentral apoptosis” after hemorrhage and resuscitation

2003 • 97 citations

Testosterone: The Crucial Hormone Responsible for Depressing Myocardial Function in Males After Trauma-Hemorrhage

1998 • 94 citations

Carbon monoxide prevents multiple organ injury in a model of hemorrhagic shock and resuscitation.

2005 • 88 citations

Alterations in tissue oxygen consumption and extraction after trauma and hemorrhagic shock

2000 • 87 citations

Insight into the mechanism by which estradiol improves organ functions after trauma-hemorrhage

2000 • 86 citations

ANDROGEN AND ESTROGEN RECEPTORS IN SPLENIC T LYMPHOCYTES: EFFECTS OF FLUTAMIDE AND TRAUMA-HEMORRHAGE

2000 • 85 citations

THE ROLE OF THE MITOCHONDRION IN TRAUMA AND SHOCK

2004 • 55 citations

Mechanism responsible for the salutary effects of flutamide on cardiac performance after trauma-hemorrhagic shock: Upregulation of cardiomyocyte estrogen receptors

2005 • 54 citations

Altered phosphorylation and calcium sensitivity of cardiac myofibrillar proteins during sepsis

2001 • 50 citations

Mitochondrial Transcription Factor A and Its Downstream Targets Are Up-regulated in a Rat Hepatoma

2002 • 50 citations

Sex Differences in Hepatic Heme Oxygenase Expression and Activity Following Trauma and Hemorrhagic Shock

2003 • 45 citations

Protective effect of urinary trypsin inhibitor on myocardial mitochondria during hemorrhagic shock and reperfusion

2003 • 44 citations

INJURY IN THE ERA OF GENOMICS

2001 • 44 citations

L-arginine restores the depressed cardiac output and regional perfusion after trauma-hemorrhage

1998 • 40 citations

Attenuation of Vascular Endothelial Dysfunction by Testosterone Receptor Blockade After Trauma and Hemorrhagic Shock

2001 • 38 citations

Measurement of hepatocellular function, cardiac output, effective blood volume, and oxygen saturation in rats

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Androgen-Induced Oxidative Stress in Human LNCaP Prostate Cancer Cells Is Associated with Multiple Mitochondrial Modifications

1999 • 36 citations

Molecular characterisation of a NADH ubiquinone oxidoreductase subunit 5 from Schistosoma mansoni and inhibition of mitochondrial respiratory chain function by testosterone.

1999 • 20 citations