NADPH oxidase activity is required for endothelial cell proliferation and migration

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

1997 • 4,504 citations

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1993 • 3,605 citations

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1994 • 3,367 citations

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

1994 • 2,753 citations

Requirement for Generation of H ₂ O ₂ for Platelet-Derived Growth Factor Signal Transduction

1995 • 2,505 citations

Antioxidant and redox regulation of gene transcription

1996 • 1,999 citations

Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway

1998 • 1,963 citations

Angiostatin induces and sustains dormancy of human primary tumors in mice

1996 • 1,193 citations

An essential role for free radicals and derived species in signal transduction

1997 • 909 citations

Oxidative Stress as a Regulator of Gene Expression in the Vasculature

1999 • 810 citations

p22 Is a Critical Component of the Superoxide-generating NADH/NADPH Oxidase System and Regulates Angiotensin IIinduced Hypertrophy in Vascular Smooth Muscle Cells

1996 • 768 citations

Oxidant Signaling in Vascular Cell Growth, Death, and Survival

2000 • 742 citations

Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol.

1994 • 647 citations

Role of NADH/NADPH Oxidase–Derived H ₂ O ₂ in Angiotensin II–Induced Vascular Hypertrophy

1998 • 616 citations

Oscillatory and Steady Laminar Shear Stress Differentially Affect Human Endothelial Redox State

1998 • 607 citations

A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial Wall

2000 • 596 citations

Reactive Oxygen Species Mediate the Activation of Akt/Protein Kinase B by Angiotensin II in Vascular Smooth Muscle Cells

1999 • 563 citations

The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase

1986 • 551 citations

Apoptosis: Activate NF-κB or die?

1997 • 524 citations

Oxidized Low Density Lipoprotein (ox-LDL) Binding to ox-LDL Receptor-1 in Endothelial Cells Induces the Activation of NF-κB through an Increased Production of Intracellular Reactive Oxygen Species

2000 • 484 citations

Halting angiogenesis suppresses carcinoma cell invasion

1997 • 430 citations

Differential Activation of Mitogen-Activated Protein Kinases by H ₂ O ₂ and O ₂ ⁻ in Vascular Smooth Muscle Cells

1995 • 416 citations

VEGF Prevents Apoptosis of Human Microvascular Endothelial Cells via Opposing Effects on MAPK/ERK and SAPK/JNK Signaling

1999 • 374 citations

rac1 Regulates a Cytokine-Stimulated, Redox-Dependent Pathway Necessary for NF-κB Activation

1996 • 337 citations

Stimulation of a Vascular Smooth Muscle Cell NAD(P)H Oxidase by Thrombin

1999 • 332 citations

Vasostatin, a Calreticulin Fragment, Inhibits Angiogenesis and Suppresses Tumor Growth

1998 • 314 citations

Tumour necrosis factor α activates a p22phox-based NADH oxidase in vascular smooth muscle

1998 • 313 citations

Antisense targeting of basic fibroblast growth factor and dibroblast growth factor receptor-1 in human melanomas blocks intratumoral angiogenesis and tumor growth

1997 • 290 citations

Endothelial NADPH Oxidase as the Source of Oxidants in Lungs Exposed to Ischemia or High K ⁺

1998 • 265 citations

Platelet-Derived Growth Factor–Stimulated Superoxide Anion Production Modulates Activation of Transcription Factor NF-κB and Expression of Monocyte Chemoattractant Protein 1 in Human Aortic Smooth Muscle Cells

1997 • 257 citations

Induction of Apoptosis by Pyrrolidinedithiocarbamate and N-Acetylcysteine in Vascular Smooth Muscle Cells

1996 • 248 citations

Overexpression of Human Catalase Inhibits Proliferation and Promotes Apoptosis in Vascular Smooth Muscle Cells

1999 • 214 citations

Inhibition of NADPH Oxidase Activation by 4-(2-Aminoethyl)-benzenesulfonyl Fluoride and Related Compounds

1997 • 196 citations

Expression of a functional neutrophil-type NADPH oxidase in cultured rat coronary microvascular endothelial cells

1998 • 188 citations

Cyclic strain induces an oxidative stress in endothelial cells

1997 • 179 citations

Shear-induced tyrosine phosphorylation in endothelial cells requires Rac1-dependent production of ROS

1999 • 150 citations

Simulated Ischemia in Flow-Adapted Endothelial Cells Leads to Generation of Reactive Oxygen Species and Cell Signaling

1999 • 143 citations

The involvement of reactive oxygen species and arachidonic acid in α₁‐adrenoceptor‐induced smooth muscle cell proliferation and migration

1997 • 101 citations