Differential behavioural and neurochemical effects of competitive and non-competitive NMDA receptor antagonists in rats

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1990 • 1,102 citations

Structure-activity relationships in the development of excitatory ammo acid receptor agonists and competitive antagonists

1990 • 905 citations

Anatomical organization of excitatory amino acid receptors and their pathways

1987 • 877 citations

A rapid method for the regional dissection of the rat brain

1980 • 540 citations

Non-competitive antagonists of excitatory amino acid receptors

1987 • 502 citations

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 496 citations

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1989 • 426 citations

Excitatory amino acid binding sites in the basal ganglia of the rat: A quantitative autoradiographic study

1992 • 369 citations

Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study

1991 • 303 citations

Central sympathomimetic activity of (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo [a, d]cyclohepten‐5,10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 229 citations

NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus

1990 • 221 citations

A Semiautomated Analysis Method for Catecholamines, Indoleamines, and Some Prominent Metabolites in Microdissected Regions of the Nervous System: An Isocratic HPLC Technique Employing Coulometric Detection and Minimal Sample Preparation

1986 • 196 citations

A simple model for studying benzodiazepines: Potentiation of hyperactivity induced by cocaine in mice

1982 • 193 citations

Amino acids : chemistry, biology and medicine

1990 • 180 citations

Anticataleptic effects of the N-methyl-D-aspartate antagonist MK-801 in rats

1989 • 168 citations

Non-competitive antagonists are potent activators of ventral tegmental A10 dopamine neurons

1990 • 157 citations

The receptor antagonist MK-801 induces increases in dopamine and serotonin metabolism in several brain regions of rats

1991 • 152 citations

Effect of the NMDA receptor antagonist, MK-801, on locomotor activity and on the metabolism of dopamine in various brain areas of mice

1991 • 141 citations

MK-801-induced stereotypy and its antagonism by neuroleptic drugs

1990 • 138 citations

Mesolimbic and mesocortical dopamine activation induced by phencyclidine: contrasting pattern to striatal response

1987 • 133 citations

Intrastriatal injection of dl-2-amino-5-phosphonovaleric acid (AP-5) induces sniffing stereotypy that is antagonized by haloperidol and clozapine

1986 • 118 citations

Interactions of Phencyclidine Receptor Agonist MK‐801 with Dopaminergic System: Regional Studies in the Rat

1990 • 112 citations

A comparison between the non-competitive NMDA antagonist dizocilpine (MK-801) and the competitive NMDA antagonist D-CPPene with regard to dopamine turnover and locomotor-stimulatory properties in mice

1991 • 88 citations

Differential stimulation of [3H]MK-801 binding to subpopulations of NMDA receptors

1991 • 79 citations

Effects of systemic and intracranial amphetamine injections on behavior in the open field: A detailed analysis

1987 • 79 citations

Mode of binding of [³H]dibenzocycloalkenimine (MK‐801) to the N‐methyl‐D‐aspartate (NMDA) receptor and its therapeutic implication

1988 • 76 citations

Behavioral pharmacological profile of CGS 19755, a competitive antagonist at N-methyl-D-aspartate receptors.

1989 • 73 citations

Role of N-methyl-d-aspartate (NMDA) receptors in experimental catalepsy in rats

1990 • 72 citations

Selective activation of dopaminergic pathways in the mesocortex by compounds that act at the phencyclidine (pcp) binding site: tentative evidence for pcp recognition sites not coupled to n-methyl-d-aspartate (nmda) receptors

1990 • 71 citations

Genetic differences in the effects of competitive and non-competitive NMDA receptor antagonists on locomotor activity in mice

1991 • 59 citations

The contribution of the different binding sites of the N-methyl-D-aspartate (NMDA) receptor to the expression of behavior

1992 • 57 citations

Effects of competitive N-methyl-d-aspartate antagonists on midbrain dopamine neurons: An electrophysiological and behavioral comparison to phencyclidine

1991 • 54 citations

Evidence for involvement of N- receptor in tonic inhibitory control of dopaminergic transmission in rat medial frontal cortex

1990 • 50 citations

Anticataleptic potencies of glutamate-antagonists

1991 • 41 citations

Dopamine release and direct dopamine receptor activation in the central nervous system by D-145, an amantadine derivative

1973 • 37 citations

Neurochemical Interactions of Competitive N‐Methyl‐D‐Aspartate Antagonists with Dopaminergic Neurotransmission and the Cerebellar Cyclic GMP System: Functional Evidence for a Phasic Glutamatergic Control of the Nigrostriatal Dopaminergic Pathway

1991 • 29 citations

Electrophysiological characterization of a novel potent and orally active NMDA receptor antagonist: CGP 37849 and its ethylester CGP 39551

1990 • 29 citations

Allosteric modulatory centers of transmitter amino acid receptors

1989 • 21 citations

Contrasting Neurochemical Interactions of Tiletamine, a Potent Phencyclidine (PCP) Receptor Ligand, with the N‐Methyl‐D‐Aspartate‐Coupled and ‐Uncoupled PCP Recognition Sites

1991 • 18 citations

Effects of systemically and intrastriatally injected haloperidol and apomorphine on grooming, feeding and locomotion in the rat

1987 • 10 citations

Cerebroprotective and anticonvulsant action of competitive and non-competitive NMDA antagonists

1990 • 10 citations