Non-competitive antagonists are potent activators of ventral tegmental A10 dopamine neurons

Manual of pharmacologic calculations with computer programs

1988 • 1,456 citations

[³H]MK‐801 Labels a Site on the N‐Methyl‐D‐Aspartate Receptor Channel Complex in Rat Brain Membranes

1988 • 453 citations

1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs.

1986 • 379 citations

Pharmacological and autoradiographic discrimination of sigma and phencyclidine receptor binding sites in brain with (+)-[3H]SKF 10,047, (+)-[3H]-3-[3-hydroxyphenyl]-N-(1-propyl)piperidine and [3H]-1-[1-(2-thienyl)cyclohexyl]piperidine.

1986 • 339 citations

Manual of pharmacologic calculations with computer programs

1988 • 297 citations

Naloxone-inaccessible sigma receptor in rat central nervous system.

1983 • 214 citations

The effects of phencyclidine and N-allylnormetazocine on midbrain dopamine neuronal activity

1984 • 181 citations

Metabolites of haloperidol display preferential activity at σ receptors compared to dopamine D-2 receptors

1990 • 149 citations

MK-801 powerfully protects against N-methyl aspartate neurotoxicity

1987 • 141 citations

Phencyclidine and σ opiate receptors in brain: Biochemical and autoradiographical differentiation

1985 • 124 citations

Subjective effects of narcotic antagonists cyclazocine and nalorphine on the Addiction Research Center Inventory (ARCI)

1970 • 124 citations

Non-competitive N-methyl-D-aspartate antagonists protect against sound-induced seizures in DBA/2 mice

1989 • 84 citations

Alterations in the stereochemistry of the .kappa.-selective opioid agonist U50,488 result in high-affinity .sigma. ligands

1989 • 73 citations

Effects of phencyclidine on ventral tegmental A10 dopamine neurons in the rat

1986 • 68 citations

A comparison of the binding of σ opioids and phencyclidine, and the interaction with antipsychotic drugs in rat brain membranes

1986 • 65 citations

Synthesis and characterization of a series of diarylguanidines that are noncompetitive N-methyl-D-aspartate receptor antagonists with neuroprotective properties.

1989 • 48 citations

Dopaminergic involvement in the mechanism of action of pentazocine

1979 • 11 citations

Do kappa opioids mimic sigma agonists as amino acid antagonists?

1986 • 9 citations