Cloning and Functional Characterization of Related TC10 Isoforms, a Subfamily of Rho Proteins Involved in Insulin-stimulated Glucose Transport

Signaling pathways in insulin action: molecular targets of insulin resistance

2000 • 932 citations

Characterization of Rac and Cdc42 Activation in Chemoattractant-stimulated Human Neutrophils Using a Novel Assay for Active GTPases

1999 • 765 citations

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

2000 • 646 citations

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

2001 • 606 citations

Molecular Basis of Insulin-stimulated GLUT4 Vesicle Trafficking

1999 • 417 citations

Moving GLUT4: The Biogenesis and Trafficking of GLUT4 Storage Vesicles

1997 • 301 citations

PTG, a Protein Phosphatase 1-Binding Protein with a Role in Glycogen Metabolism

1997 • 293 citations

Characterization of Four Novel ras-Like Genes Expressed in a Human Teratocarcinoma Cell Line

1990 • 285 citations

A Novel, Multifunctional c-Cbl Binding Protein in Insulin Receptor Signaling in 3T3-L1 Adipocytes

1998 • 216 citations

Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles

2001 • 187 citations

Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation

2001 • 171 citations

Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles

2001 • 165 citations

Insulin stimulates tyrosine phosphorylation of the proto-oncogene product of c-Cbl in 3T3-L1 adipocytes

1997 • 155 citations

The sorbin homology domain: A motif for the targeting of proteins to lipid rafts

2001 • 151 citations

The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake.

1995 • 149 citations

Membrane-permeant Esters of Phosphatidylinositol 3,4,5-Trisphosphate

1998 • 149 citations

Activation of Mitogen-activated Protein Kinase and Phosphatidylinositol 3′-Kinase Is Not Sufficient for the Hormonal Stimulation of Glucose Uptake, Lipogenesis, or Glycogen Synthesis in 3T3-L1 Adipocytes

1995 • 148 citations

Insulin-stimulated Tyrosine Phosphorylation of Caveolin Is Specific for the Differentiated Adipocyte Phenotype in 3T3-L1 Cells

1997 • 143 citations

Stimulation of IRS-1-associated Phosphatidylinositol 3-Kinase and Akt/Protein Kinase B but Not Glucose Transport by β1-Integrin Signaling in Rat Adipocytes

1998 • 122 citations

Characterization of TCL, a New GTPase of the Rho Family related to TC10 and Cdc42

2000 • 120 citations

Munc18c Function Is Required for Insulin-Stimulated Plasma Membrane Fusion of GLUT4 and Insulin-Responsive Amino Peptidase Storage Vesicles

2000 • 104 citations

Two Naturally Occurring Insulin Receptor Tyrosine Kinase Domain Mutants Provide Evidence That Phosphoinositide 3-Kinase Activation Alone Is Not Sufficient for the Mediation of Insulin's Metabolic and Mitogenic Effects

1997 • 92 citations

Insulin Stimulates Actin Comet Tails on Intracellular GLUT4-containing Compartments in Differentiated 3T3L1 Adipocytes

2001 • 80 citations

Spatial compartmentalization of signal transduction in insulin action

2001 • 75 citations

The Small GTP-Binding Protein TC10 Promotes Nerve Elongation in Neuronal Cells, and Its Expression Is induced during Nerve Regeneration in Rats

2000 • 74 citations

Guanosine 5′-O-(3-Thiotriphosphate) (GTPγS) Stimulation of GLUT4 Translocation is Tyrosine Kinase-dependent

1998 • 69 citations

Divergent signalling mechanisms involved in insulin-stimulated GLUT4 vesicle trafficking to the plasma membrane

1999 • 9 citations