Insulin Stimulates Actin Comet Tails on Intracellular GLUT4-containing Compartments in Differentiated 3T3L1 Adipocytes

The Interaction between N-WASP and the Arp2/3 Complex Links Cdc42-Dependent Signals to Actin Assembly

1999 • 1,332 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

Exercise, Glucose Transport, and Insulin Sensitivity

1998 • 1,066 citations

Reconstitution of actin-based motility of Listeria and Shigella using pure proteins

1999 • 968 citations

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

2000 • 646 citations

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

2001 • 606 citations

Kinetic Analysis of Secretory Protein Traffic and Characterization of Golgi to Plasma Membrane Transport Intermediates in Living Cells

1998 • 603 citations

Activation of the Cdc42 Effector N-Wasp by the Shigella flexneri Icsa Protein Promotes Actin Nucleation by Arp2/3 Complex and Bacterial Actin-Based Motility

1999 • 513 citations

Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3

2000 • 501 citations

Actin-Dependent Propulsion of Endosomes and Lysosomes by Recruitment of N-Wasp✪

2000 • 444 citations

Molecular Basis of Insulin-stimulated GLUT4 Vesicle Trafficking

1999 • 417 citations

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling

1999 • 407 citations

Chromaffin cell cortical actin network dynamics control the size of the release-ready vesicle pool and the initial rate of exocytosis

1995 • 341 citations

A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

2000 • 318 citations

Translocation of the glucose transporter (GLUT4) to the cell surface in permeabilized 3T3-L1 adipocytes: effects of ATP insulin, and GTP gamma S and localization of GLUT4 to clathrin lattices

1992 • 307 citations

Moving GLUT4: The Biogenesis and Trafficking of GLUT4 Storage Vesicles

1997 • 301 citations

Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action.

1993 • 297 citations

Insulin-stimulated GLUT4 Translocation in Adipocytes Is Dependent upon Cortical Actin Remodeling

2001 • 279 citations

A comparative study of the actin-based motilities of the pathogenic bacteria Listeria monocytogenes, Shigella flexneri and Rickettsia conorii

1999 • 257 citations

Comparison of GLUT4 and GLUT1 subcellular trafficking in basal and insulin-stimulated 3T3-L1 cells.

1993 • 252 citations

Effects of insulin on steady state kinetics of GLUT4 subcellular distribution in rat adipocytes. Evidence of constitutive GLUT4 recycling.

1992 • 225 citations

Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri

1998 • 224 citations

Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin.

1991 • 223 citations

Corequirement of Specific Phosphoinositides and Small GTP-binding Protein Cdc42 in Inducing Actin Assembly in Xenopus Egg Extracts

1998 • 219 citations

Insulin-induced actin filament remodeling colocalizes actin with phosphatidylinositol 3-kinase and GLUT4 in L6 myotubes

2000 • 213 citations

Control of actin dynamics

1998 • 206 citations

Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters to the plasma membrane.

1994 • 204 citations

The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42

1998 • 188 citations

Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles

2001 • 187 citations

Synip

1999 • 183 citations

Secrets of actin-based motility revealed by a bacterial pathogen

2000 • 171 citations

Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles

2001 • 165 citations

Insulin-Responsive Compartments Containing GLUT4 in 3T3-L1 and CHO Cells: Regulation by Amino Acid Concentrations

2001 • 158 citations

Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes

1998 • 155 citations

Actin filaments play a critical role in insulin-induced exocytotic recruitment but not in endocytosis of GLUT4 in isolated rat adipocytes

2000 • 151 citations

Insulin action on the internalization of the GLUT4 glucose transporter in isolated rat adipocytes

1993 • 149 citations

Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake

2000 • 142 citations

Distinct cellular effects and interactions of the Rho-family GTPase TC10

1998 • 140 citations

Insulin and nonhydrolyzable GTP analogs induce translocation of GLUT 4 to the plasma membrane in alpha-toxin-permeabilized rat adipose cells

1991 • 139 citations

The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways.

1996 • 130 citations

Perinuclear Localization and Insulin Responsiveness of GLUT4 Requires Cytoskeletal Integrity in 3T3-L1 Adipocytes

2000 • 128 citations

Insulin receptor substrate-1 (IRS1) and Shc compete for a limited pool of Grb2 in mediating insulin downstream signaling.

1994 • 109 citations

Insulin Action on GLUT4 Traffic Visualized in Single 3T3-L1 Adipocytes by Using Ultra-fast Microscopy

2001 • 107 citations

Comparison of glucose-transporter-containing vesicles from rat fat and muscle tissues: evidence for a unique endosomal compartment

1995 • 103 citations

A Role for Kinesin in Insulin-stimulated GLUT4 Glucose Transporter Translocation in 3T3-L1 Adipocytes

2001 • 102 citations

GLUT4 – At the Cross Roads Between Membrane Trafficking and Signal Transduction

2001 • 102 citations

Cycling of actin assembly in synaptosomes and neurotransmitter release

1989 • 95 citations

Insulin-mediated GLUT4 Translocation Is Dependent on the Microtubule Network

2001 • 92 citations

Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression

1998 • 70 citations

Guanosine 5′-O-(3-Thiotriphosphate) (GTPγS) Stimulation of GLUT4 Translocation is Tyrosine Kinase-dependent

1998 • 69 citations

Dissection of GLUT4 Recycling Pathway into Exocytosis and Endocytosis in Rat Adipocytes

1995 • 57 citations

Cdc42 is required for membrane dependent actin polymerization in vitro

1998 • 44 citations