Sp3 repression of polymorphic human NRH:quinone oxidoreductase 2 gene promoter

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

The Sp-family of transcription factors

1999 • 1,098 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

Sp1-mediated transcriptional activation is repressed by Sp3.

1994 • 692 citations

Regulation of γ-Glutamylcysteine Synthetase Subunit Gene Expression by the Transcription Factor Nrf2

1999 • 584 citations

Multiple specific contacts between a mammalian transcription factor and its cognate promoters

1984 • 565 citations

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

1992 • 533 citations

Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2

2000 • 515 citations

Chemoprotection against cancer by Phase 2 enzyme induction

1995 • 454 citations

Regulation of genes encoding NAD(P)H:quinone oxidoreductases

2000 • 419 citations

Transcriptional Regulation of the Antioxidant Response Element

2000 • 364 citations

Transcriptional initiation is controlled by upstream GC-box interactions in a TATAA-less promoter.

1990 • 270 citations

Disruption of the DT Diaphorase (NQO1) Gene in Mice Leads to Increased Menadione Toxicity

1998 • 262 citations

Functional Analyses of the Transcription Factor Sp4 Reveal Properties Distinct from Sp1 and Sp3

1995 • 208 citations

Small Maf (MafG and MafK) Proteins Negatively Regulate Antioxidant Response Element-mediated Expression and Antioxidant Induction of the NAD(P)H:Quinone Oxidoreductase1 Gene

2000 • 205 citations

In Vivo Role of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) in the Regulation of Intracellular Redox State and Accumulation of Abdominal Adipose Tissue

2001 • 195 citations

Sp1 Trans-Activation of Cell Cycle Regulated Promoters Is Selectively Repressed by Sp3

1995 • 193 citations

NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis.

2000 • 139 citations

Enzyme-directed bioreductive drug development revisited: a commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes, particularly DT-diaphorase.

1994 • 127 citations

Start site selection by Sp1 in the TATA-less human Ha-ras promoter.

1994 • 126 citations

Sp3 and Sp4 Can Repress Transcription by Competing with Sp1 for the Core cis-Elements on the Human ADH5/FDHMinimal Promoter

1999 • 126 citations

An Association between Idiopathic Parkinson's Disease and Polymorphisms of Phase II Detoxification Enzymes: Glutathione S-Transferase M1 and Quinone Oxidoreductase 1 and 2

2001 • 123 citations

Human NAD(P)H:quinone oxidoreductase2. Gene structure, activity, and tissue-specific expression.

1994 • 117 citations

NAD(P)H : quinone Oxidoreductase 1 Deficiency and Increased Susceptibility to 7,12-Dimethylbenz[a]-anthracene-Induced Carcinogenesis in Mouse Skin

2001 • 116 citations

NRH:quinone oxidoreductase2 (NQO2)

2000 • 112 citations

Disruption of Dihydronicotinamide Riboside:Quinone Oxidoreductase 2 (NQO2) Leads to Myeloid Hyperplasia of Bone Marrow and Decreased Sensitivity to Menadione Toxicity

2002 • 109 citations

Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies.

1994 • 106 citations

DT-diaphorase: possible roles in cancer chemotherapy and carcinogenesis.

1997 • 72 citations

The Human POLD1 Gene

1997 • 70 citations

The Sp family of transcription factors in the regulation of the human and mouse MUC2 gene promoters.

2001 • 55 citations

Sp3 Represses Gene Expression via the Titration of Promoter-specific Transcription Factors

2002 • 36 citations

Regulation of Mouse Ah Receptor (Ahr) Gene Basal Expression by Members of the Sp Family of Transcription Factors

1998 • 33 citations