Feedback Phosphorylation of an RGS Protein by MAP Kinase in Yeast

The MAPK signaling cascade

1995 • 3,300 citations

PEST sequences and regulation by proteolysis

1996 • 1,606 citations

Method to Correlate Tandem Mass Spectra of Modified Peptides to Amino Acid Sequences in the Protein Database

1995 • 1,269 citations

G Protein-coupled Receptors

1998 • 1,033 citations

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

p21-containing cyclin kinases exist in both active and inactive states.

1994 • 646 citations

RGS Proteins and Signaling by Heterotrimeric G Proteins

1997 • 522 citations

Mammalian RGS Proteins: Barbarians at the Gate

1998 • 487 citations

MAP Kinases with Distinct Inhibitory Functions Impart Signaling Specificity during Yeast Differentiation

1997 • 434 citations

Sst2, a Negative Regulator of Pheromone Signaling in the Yeast Saccharomyces cerevisiae: Expression, Localization, and Genetic Interaction and Physical Association with Gpa1 (the G-Protein α Subunit)

1996 • 331 citations

Isolation and Genetic Analysis of Saccharomyces cerevisiae Mutants Supersensitive to G1 Arrest by a Factor and α Factor Pheromones

1982 • 322 citations

Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.

1992 • 292 citations

FAR1 links the signal transduction pathway to the cell cycle machinery in yeast

1993 • 290 citations

[5] Assay of yeast mating reaction

1991 • 286 citations

FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1.

1993 • 274 citations

Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous- growth signalling pathway

1997 • 270 citations

Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae.

1996 • 229 citations

Pheromonal regulation and sequence of the Saccharomyces cerevisiae SST2 gene: a model for desensitization to pheromone.

1987 • 212 citations

Inhibition of G-Protein Signaling by Dominant Gain-of-Function Mutations in Sst2p, a Pheromone Desensitization Factor in Saccharomyces cerevisiae

1995 • 198 citations

A dominant truncation allele identifies a gene, STE20, that encodes a putative protein kinase necessary for mating in Saccharomyces cerevisiae.

1993 • 189 citations

Protein identification by solid phase microextraction—capillary zone electrophoresis—microelectrospray—tandem mass spectrometry

1996 • 184 citations

Far1 and Fus3 link the mating pheromone signal transduction pathway to three G1-phase Cdc28 kinase complexes.

1993 • 174 citations

A Point Mutation in Gαo and Gαi1Blocks Interaction with Regulator of G Protein Signaling Proteins

1998 • 172 citations

A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae.

1992 • 168 citations

Interaction between RGS7 and polycystin

1999 • 164 citations

Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases.

1993 • 146 citations

Feedback Regulation of β-Arrestin1 Function by Extracellular Signal-regulated Kinases

1999 • 136 citations

Sst2 Is a GTPase-Activating Protein for Gpa1: Purification and Characterization of a Cognate RGS−Gα Protein Pair in Yeast

1998 • 124 citations

Selective Uncoupling of RGS Action by a Single Point Mutation in the G Protein α-Subunit

1998 • 116 citations

Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway.

1995 • 86 citations

Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway.

1994 • 69 citations

Optimization of solid phase microextraction - capillary zone electrophoresis - mass spectrometry for high sensitivity protein identification

1998 • 50 citations

Control of MAP kinase signaling specificity or how not to go HOG wild: Figure 1.

1998 • 43 citations

Second Site Suppressor Mutations of a GTPase-deficient G-Protein α-Subunit

1998 • 30 citations

Identification and expression of G protein-coupled receptors

1998 • 28 citations