Ceramide induces apoptosis in PC12 cells

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Programmed Cell Death and the Control of Cell Survival: Lessons from the Nervous System

1993 • 1,470 citations

The molecular biology of apoptosis.

1996 • 963 citations

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

1995 • 835 citations

Induction of Apoptosis by the Low-Affinity NGF Receptor

1993 • 774 citations

A Selective Procedure for DNA Extraction from Apoptotic Cells Applicable for Gel Electrophoresis and Flow Cytometry

1994 • 670 citations

Ceramide: an intracellular signal for apoptosis

1995 • 604 citations

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

1994 • 583 citations

Signal transduction through lipid second messengers

1996 • 496 citations

Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32

1996 • 481 citations

ICE Family Proteases: Mediators of All Apoptotic Cell Death?

1996 • 440 citations

Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death.

1996 • 371 citations

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development.

1994 • 371 citations

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1991 • 337 citations

Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide.

1993 • 305 citations

Neurotrophins Induce Sphingomyelin Hydrolysis

1995 • 245 citations

prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2

1996 • 203 citations

Internucleosomal DNA cleavage and neuronal cell survival/death

1993 • 194 citations

Ceramide Induces Apoptosis in Cultured Mesencephalic Neurons

1996 • 191 citations

Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle.

1994 • 174 citations

Staurosporine Induces Programmed Cell Death in Embryonic Neurons and Activation of the Ceramide Pathway

1996 • 174 citations

A Mediator Role of Ceramide in the Regulation of Neuroblastoma Neuro2a Cell Differentiation

1995 • 165 citations

An ICE‐like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP.1 cells

1995 • 158 citations

Induction of apoptotic DNA fragmentation and cell death by natural ceramide

1995 • 158 citations

Role of multiple cellular proteases in the execution of programmed cell death

1995 • 141 citations

A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells

1995 • 138 citations

Modulation of cell growth and differentiation by ceramide

1992 • 99 citations

Nerve Growth Factor (NGF)-Mediated Protection of Neural Crest Cells from Antimitotic Agent-Induced Apoptosis: The Role of the Low-Affinity NGF Receptor

1996 • 88 citations

A cleavage-site-directed inhibitor of interleukin-1β-converting enzyme-like proteases inhibits apoptosis in primary cultures of rat hepatocytes

1996 • 76 citations

Inhibition of NGF-induced neurite outgrowth of PC12 cells by Bacillus cereus sphingomyelinase, a bacterial hemolysin

1994 • 14 citations