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Upstream and downstream of mTOR

2004 • 4,085 citations

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

2003 • 3,104 citations

IRF-7 is the master regulator of type-I interferon-dependent immune responses

2005 • 2,108 citations

Innate immune recognition of viral infection

2006 • 1,790 citations

Plasmacytoid dendritic cells in immunity

2004 • 1,645 citations

IPC: Professional Type 1 Interferon-Producing Cells and Plasmacytoid Dendritic Cell Precursors

2004 • 1,635 citations

Growing roles for the mTOR pathway

2005 • 1,526 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

2004 • 1,326 citations

Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction

2000 • 1,304 citations

Danger signals: SOS to the immune system

2001 • 1,198 citations

Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

2001 • 1,017 citations

Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

2004 • 994 citations

Regulation of cap-dependent translation by eIF4E inhibitory proteins

2005 • 944 citations

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation

1999 • 928 citations

Type I Interferon in Systemic Lupus Erythematosus and Other Autoimmune Diseases

2006 • 926 citations

Spatiotemporal regulation of MyD88–IRF-7 signalling for robust type-I interferon induction

2005 • 886 citations

Cyclosporin A, FK-506, and Rapamycin: Pharmacologic Probes of Lymphocyte Signal Transduction

1992 • 675 citations

Rapamune® (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression

1998 • 664 citations

mTOR, translation initiation and cancer

2006 • 592 citations

Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity

2006 • 527 citations

mTOR Complex1–S6K1 signaling: at the crossroads of obesity, diabetes and cancer

2007 • 473 citations

Yellow fever vaccine

2005 • 455 citations

eIF4E – from translation to transformation

2004 • 439 citations

Rapamycin-Conditioned Dendritic Cells Are Poor Stimulators of Allogeneic CD4+ T Cells, but Enrich for Antigen-Specific Foxp3+ T Regulatory Cells and Promote Organ Transplant Tolerance

2007 • 416 citations

Most lymphoid organ dendritic cell types are phenotypically and functionally immature

2003 • 362 citations

Osteopontin expression is essential for interferon-α production by plasmacytoid dendritic cells

2006 • 333 citations

Translational control of the innate immune response through IRF-7

2008 • 312 citations

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K

2002 • 293 citations

Nanoparticles and microparticles as vaccine-delivery systems

2007 • 250 citations

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

2008 • 215 citations

Plasmacytoid dendritic cell precursors/type I interferon-producing cells sense viral infection by Toll-like receptor (TLR) 7 and TLR9

2004 • 210 citations

Role of Phosphoinositide 3-Kinase in Innate Immunity

2007 • 186 citations

Cutting Edge: Cooperation of IPS-1- and TRIF-Dependent Pathways in Poly IC-Enhanced Antibody Production and Cytotoxic T Cell Responses

2008 • 151 citations

Phosphorylation-Induced Dimerization of Interferon Regulatory Factor 7 Unmasks DNA Binding and a Bipartite Transactivation Domain

2000 • 142 citations

Modified Vaccinia Virus Ankara Induces Toll-Like Receptor-Independent Type I Interferon Responses

2007 • 120 citations

The mammalian target of the rapamycin (mTOR) kinase pathway: its role in tumourigenesis and targeted antitumour therapy.

2005 • 104 citations

The multifaceted role of mTOR in cellular stress responses

2004 • 93 citations

Now I know my CpGs

2001 • 80 citations

mTOR — beyond transplantation

2005 • 41 citations