Osteopontin expression is essential for interferon-α production by plasmacytoid dendritic cells

Toll-like receptor control of the adaptive immune responses

2004 • 4,092 citations

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

2000 • 3,456 citations

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

2003 • 2,133 citations

Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes

2003 • 1,999 citations

Plasmacytoid dendritic cells in immunity

2004 • 1,645 citations

IPC: Professional Type 1 Interferon-Producing Cells and Plasmacytoid Dendritic Cell Precursors

2004 • 1,635 citations

TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITY

2004 • 1,157 citations

Eta-1 (Osteopontin): An Early Component of Type-1 (Cell-Mediated) Immunity

2000 • 1,104 citations

Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival

2001 • 1,048 citations

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

2005 • 973 citations

Spatiotemporal regulation of MyD88–IRF-7 signalling for robust type-I interferon induction

2005 • 886 citations

Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon

2003 • 787 citations

TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function

2004 • 719 citations

Cd11c+B220+Gr-1+ Cells in Mouse Lymph Nodes and Spleen Display Characteristics of Plasmacytoid Dendritic Cells

2001 • 717 citations

Generation of Human CD8 T Regulatory Cells by CD40 Ligand–activated Plasmacytoid Dendritic Cells

2002 • 659 citations

Pathogen recognition with Toll-like receptors

2005 • 565 citations

Flexibility of Mouse Classical and Plasmacytoid-derived Dendritic Cells in Directing T Helper Type 1 and 2 Cell Development

2003 • 561 citations

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

2004 • 520 citations

Mice Lacking Osteopontin Show Normal Development and Bone Structure but Display Altered Osteoclast Formation In Vitro

1998 • 426 citations

Regulation of the type I IFN induction: a current view

2005 • 342 citations

The Roles of Toll-Like Receptor 9, MyD88, and DNA-Dependent Protein Kinase Catalytic Subunit in the Effects of Two Distinct CpG DNAs on Dendritic Cell Subsets

2003 • 341 citations

Analysis of regulatory CD8 T cells in Qa-1-deficient mice

2004 • 330 citations

Autoimmunity through Cytokine-Induced Dendritic Cell Activation

2004 • 294 citations

A Subset of Toll-Like Receptor Ligands Induces Cross-presentation by Bone Marrow-Derived Dendritic Cells

2003 • 292 citations

Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration

2000 • 272 citations

Divergent Therapeutic and Immunologic Effects of Oligodeoxynucleotides with Distinct CpG Motifs

2001 • 252 citations

T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells

2003 • 250 citations

Multiple Sclerosis: Deeper Understanding of Its Pathogenesis Reveals New Targets for Therapy

2002 • 242 citations

Type I IFN Protects Against Murine Lupus

2004 • 200 citations

CpG-matured Murine Plasmacytoid Dendritic Cells Are Capable of In Vivo Priming of Functional CD8 T Cell Responses to Endogenous but Not Exogenous Antigens

2004 • 198 citations

Interferons as pathogenic effectors in autoimmunity

2005 • 198 citations

Bone marrow plasmacytoid dendritic cells can differentiate into myeloid dendritic cells upon virus infection

2004 • 196 citations

Osteopontin as a Mediator of NKT Cell Function in T Cell-Mediated Liver Diseases

2004 • 190 citations

Plasma osteopontin levels in multiple sclerosis

2004 • 181 citations

Osteopontin modulates CD44‐dependent chemotaxis of peritoneal macrophages through G‐protein‐coupled receptors: Evidence of a role for an intracellular form of osteopontin

2003 • 167 citations

Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype

2005 • 166 citations

Osteopontin: a bridge between bone and the immune system

2003 • 161 citations

Attenuated Host Resistance againstMycobacterium bovisBCG Infection in Mice Lacking Osteopontin

1999 • 153 citations

Colocalization of Intracellular Osteopontin With CD44 Is Associated With Migration, Cell Fusion, and Resorption in Osteoclasts

2002 • 152 citations

T-bet-dependent expression of osteopontin contributes to T cell polarization

2005 • 143 citations

Role of osteopontin in amplification and perpetuation of rheumatoid synovitis

2005 • 135 citations

Osteopontin: a bridge between bone and the immune system

2003 • 133 citations

Osteopontin Is Involved in the Initiation of Cutaneous Contact Hypersensitivity by Inducing Langerhans and Dendritic Cell Migration to Lymph Nodes

2001 • 130 citations

Role of osteopontin in amplification and perpetuation of rheumatoid synovitis

2005 • 122 citations

Dendritic cells respond to influenza virus through TLR7‐ and PKR‐independent pathways

2004 • 116 citations

IFN-αβ Promote Priming of Antigen-Specific CD8+ and CD4+ T Lymphocytes by Immunostimulatory DNA-Based Vaccines

2002 • 115 citations

Shaping of adaptive immune responses to soluble proteins by TLR agonists: A role for IFN‐α/β

2004 • 101 citations

Cutting Edge: Toll-Like Receptor 9 Expression Is Not Required for CpG DNA-Aided Cross-Presentation of DNA-Conjugated Antigens but Essential for Cross-Priming of CD8 T Cells

2003 • 99 citations

Upregulated renal tubular CD44, hyaluronan, and osteopontin in kdkd mice with interstitial nephritis

1997 • 93 citations

A functional role for osteopontin in experimental crescentic glomerulonephritis in the rat.

1998 • 87 citations

Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice

2005 • 75 citations

Effects of a Hexameric Deoxyriboguanosine Run Conjugation into CpG Oligodeoxynucleotides on Their Immunostimulatory Potentials

2000 • 74 citations

Osteopontin expression in human crescentic glomerulonephritis

2000 • 65 citations

The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells

2005 • 58 citations

Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes

2004 • 54 citations

Inhibition of Lupus by Genetic Alteration of the Interferon-α/β Receptor

2003 • 38 citations

Deficiency of type I interferon contributes to Sle2‐associated component lupus phenotypes

2005 • 38 citations

The importance of being a pDC in antiviral immunity: the IFN mission versus Ag presentation?

2005 • 36 citations

Osteopontin Is Not Required for the Development of Th1 Responses and Viral Immunity

2005 • 32 citations

Identification of differentially expressed genes representing dendritic cell precursors and their progeny

2003 • 28 citations

T-cell receptor crossreactivity and autoimmune disease

2000 • 24 citations

Deleted Work

1955 • 0 citations