Activation of Human Neutrophil Procollagenase by Nitrogen Dioxide and Peroxynitrite: A Novel Mechanism for Procollagenase Activation Involving Nitric Oxide

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1992 • 2,725 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Peroxynitrite oxidation of sulfhydryls.

1991 • 2,479 citations

Endothelium‐derived relaxing and contracting factors

1989 • 2,017 citations

Redox signaling: Nitrosylation and related target interactions of nitric oxide

1994 • 1,732 citations

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

1990 • 1,423 citations

Nitric oxide activates cyclooxygenase enzymes.

1993 • 1,416 citations

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

1992 • 1,319 citations

Oxidants in Cigarette Smoke Radicals, Hydrogen Peroxide, Peroxynitrate, and Peroxynitritea

1993 • 1,142 citations

A Fluorometric Assay for the Measurement of Nitrite in Biological Samples

1993 • 1,022 citations

Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum

1991 • 875 citations

Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide

1992 • 702 citations

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation.

1990 • 699 citations

Peroxynitrite‐mediated oxidative protein modifications

1995 • 611 citations

Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide.

1994 • 596 citations

New nitric oxide-releasing zwitterions derived from polyamines

1993 • 587 citations

Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not.

1994 • 585 citations

Peroxynitrite Reaction with Carbon Dioxide/Bicarbonate: Kinetics and Influence on Peroxynitrite-Mediated Oxidations

1996 • 583 citations

Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.bul.NO (nitric oxide) through a radical reaction

1993 • 569 citations

Oxidative Autoactivation of Latent Collagenase by Human Neutrophils

1985 • 466 citations

Expression of matrix metalloproteinase-2 and -9 during early human wound healing.

1994 • 411 citations

Nitric Oxide Activates Metalloprotease Enzymes in Articular Cartilage

1995 • 410 citations

Stepwise activation mechanisms of the precursor of matrix metalloproteinase 3 (stromelysin) by proteinases and (4-aminophenyl)mercuric acetate

1990 • 381 citations

Generation of nitric oxide by human neutrophils

1989 • 298 citations

Interactions of peroxynitrite with human plasma and its constituents: oxidative damage and antioxidant depletion

1994 • 287 citations

Activation of purified guanylate cyclase by nitric oxide requires heme comparison of heme-deficient, heme-reconstituted and heme-containing forms of soluble enzyme from bovine lung

1982 • 262 citations

Relation of Smoking and Age to Emphysema

1972 • 201 citations

Biological effects of cigarette smoke, wood smoke, and the smoke from plastics: The use of electron spin resonance

1992 • 179 citations

Effects of Tetracyclines on Neutrophil, Gingival, and Salivary Collagenases

1994 • 172 citations

Determination of nitric oxide using fluorescence spectroscopy

1996 • 172 citations

Activation of Human Matrix Metalloproteinases by Various Bacterial Proteinases

1997 • 170 citations

Reaction of Nitric Oxide with the Free Sulfhydryl Group of Human Serum Albumin Yields a Sulfenic Acid and Nitrous Oxide

1995 • 146 citations

Activation of latent human neutrophil collagenase by reactive oxygen species and serine proteases

1990 • 137 citations

Hydroxyl radical production by H2O2 plus Cu,Zn-superoxide dismutase reflects the activity of free copper released from the oxidatively damaged enzyme.

1992 • 134 citations

Bactericidal activity of alkyl peroxyl radicals generated by heme-iron-catalyzed decomposition of organic peroxides

1992 • 120 citations

Proteolytic inactivation of alpha 1-proteinase inhibitor and alpha 1-antichymotrypsin by oxidatively activated human neutrophil metalloproteinases.

1992 • 114 citations

Quantitation of nitric oxide using 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide (PTIO)

1996 • 102 citations

Characterization and activation of procollagenase from human polymorphonuclear leucocytes

1990 • 101 citations

Multiple functions of nitric oxide in pathophysiology and microbiology: analysis by a new nitric oxide scavenger

1994 • 93 citations

Reaction of tetranitromethane with sulfhydryl groups in proteins

1969 • 91 citations

Effects of thiols, sugars, and proteins on nitric oxide activation of guanylate cyclase.

1979 • 90 citations

Damage of amino acids and proteins induced by nitrogen dioxide, a free radical toxin, in air

1994 • 84 citations

In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2.

1993 • 82 citations

Pronounced enhancement of .NO-dependent antimicrobial action by an .NO-oxidizing agent, imidazolineoxyl N-oxide

1993 • 76 citations

Cigarette Smoke Activates Guanylate Cyclase and Increases Guanosine 3′,5′-Monophosphate in Tissues

1977 • 60 citations

Modulatory Role of Nitric Oxide on Superoxide-Dependent Luminol Chemiluminescence

1996 • 55 citations

Thermodynamic considerations on the formation of reactive species from hypochlorite, superoxide and nitrogen monoxide Could nitrosyl chloride be produced by neutrophils and macrophages?

1994 • 54 citations

Purification to homogeneity of latent and active 58-kilodalton forms of human neutrophil collagenase

1990 • 43 citations

Cyclic GMP Elevation by 5-Hydroxytryptamine Is Due to Nitric Oxide Derived from Endogenous Nitrosothiol in NG108-15 Cells

1996 • 17 citations

Nitrogen Dioxide Reactivity with Proteins: Effects on Activity and Immunoreactivity with α-1-Proteinase Inhibitor and Implications for NO2-Mediated Peptide Degradation

1993 • 16 citations

Collagenase in Rheumatoid Arthritis

1985 • 8 citations