Purification to homogeneity of latent and active 58-kilodalton forms of human neutrophil collagenase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Ultrasensitive Stain for Proteins in Polyacrylamide Gels Shows Regional Variation in Cerebrospinal Fluid Proteins

1981 • 2,972 citations

A simplified method for cyanogen bromide activation of agarose for affinity chromatography

1974 • 1,951 citations

The stabilization of proteins by sucrose.

1981 • 1,084 citations

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation.

1990 • 699 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase.

1985 • 625 citations

Oxidative Autoactivation of Latent Collagenase by Human Neutrophils

1985 • 466 citations

Human skin collagenase: isolation of precursor and active forms from both fibroblast and organ cultures

1977 • 387 citations

The collagen substrate specificity of human skin fibroblast collagenase.

1981 • 371 citations

Human Granulocyte Collagenase

1968 • 335 citations

The collagen substrate specificity of human neutrophil collagenase.

1987 • 285 citations

An endopeptidase from rheumatoid synovial tissue culture

1972 • 252 citations

Human skin fibroblast procollagenase: mechanisms of activation by organomercurials and trypsin

1983 • 208 citations

Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens

1982 • 203 citations

Detergent-activation of latent collagenase and resolution of its component molecules

1982 • 202 citations

Granulocyte collagenase: selective digestion of type I relative to type III collagen.

1977 • 201 citations

The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products.

1987 • 173 citations

Collagenase is a component of the specific granules of human neutrophil leucocytes

1977 • 173 citations

The latent collagenase and gelatinase of human polymorphonuclear neutrophil leucocytes

1980 • 168 citations

Secreted forms of human neutrophil collagenase.

1986 • 167 citations

[8] Catabolism and turnover of collagens: Collagenases

1987 • 151 citations

Synthesis of collagenase and collagenase inhibitors by osteoblast-like cells in culture

1984 • 125 citations

Sequence specificity of human skin fibroblast collagenase. Evidence for the role of collagen structure in determining the collagenase cleavage site.

1987 • 120 citations

Phagocytic Release and Activation of Human Leukocyte Procollagenase

1973 • 115 citations

Purification of human collagenases with a hydroxamic acid affinity column

1986 • 114 citations

The gelatinolytic activity of human skin fibroblast collagenase.

1982 • 105 citations

Characterization and activation of procollagenase from human polymorphonuclear leucocytes

1990 • 101 citations

Monoclonal antibodies to human fibroblast procollagenase. Inhibition of enzymatic activity, affinity purification of the enzyme, and evidence for clustering of epitopes in the amino-terminal end of the activated enzyme

1988 • 91 citations

Purification of pig synovial collagenase to high specific activity

1979 • 91 citations

Metal binding stoichiometry and mechanism of metal ion modulation of the activity of porcine kidney leucine aminopeptidase

1981 • 89 citations

Latent and Active Human Polymorphonuclear Leukocyte Collagenases

1983 • 87 citations

Monocyte procollagenase and tissue inhibitor of metalloproteinases. Identification, characterization, and regulation of secretion.

1987 • 79 citations

Human leukocyte collagenase: Characterization of enzyme kinetics by a new method

1977 • 75 citations

Heterogeneity among human collagenases demonstrated by monoclonal antibody that selectively recognizes and inhibits human neutrophil collagenase.

1984 • 61 citations

Secretion of Collagenolytic Enzymes by Human Polymorphonuclear Leukocytes

1984 • 59 citations

Partial purification and characterization of a chymotrypsin-like enzyme from human neutrophil leucocytes

1974 • 59 citations

Degradation of type I collagen by rat mucosal keratinocytes. Evidence for secretion of a specific epithelial collagenase.

1987 • 53 citations

Molecular cloning of human synovial cell collagenase and selection of a single gene from genomic DNA.

1987 • 51 citations

Proteolytic activities of human fibroblast collagenase: hydrolysis of a broad range of substrates at a single active site

1990 • 44 citations

Mechanism of inhibition of human neutrophil collagenase by Gold(I) chrysotherapeutic compounds

1989 • 41 citations

Separation of the Human Leucocy te Enzymes. Alanine Aminopeptidase, Cathepsin G, Collagenase, Elastase and Myeloperoxidase

1982 • 40 citations

Accurate, quantitative assays for the hydrolysis of soluble type I, II, and III 3H-acetylated collagens by bacterial and tissue collagenases

1986 • 34 citations

Activation of Latent Collagenase Purified from Human Leukocytes

1987 • 28 citations

Purification of human neutrophil collagenase and production of a monospecific antiserum

1982 • 26 citations

Human polymorphonuclear leukocyte collagenase and gelatinase

1984 • 20 citations

The immunologic relationship of human neutrophil and skin collagenases

1987 • 17 citations

Use of lectin affinity chromatography for the purification of collagenase from human polymorphonuclear leukocytes

1986 • 12 citations

Functional constituents of the active site of human neutrophil collagenase

1986 • 10 citations

Kinetics of Collagenase and Neutral Protease Release by Neutrophils Exposed to Microcrystalline Sodium Urate

1983 • 6 citations