Expression and functional roles of neural cell surface molecules and extracellular matrix components during development and regeneration of peripheral nerves

Society for Neuroscience 2007 abstracts

2007 • 2,107 citations

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

The Fine Structure of the Nervous System.

1970 • 1,971 citations

A differentiation antigen of human NK and K cells identified by a monoclonal antibody (HNK-1).

1981 • 1,411 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors

1990 • 1,232 citations

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

1991 • 1,171 citations

Neural Cell Adhesion Molecule: Structure, Immunoglobulin-Like Domains, Cell Surface Modulation, and Alternative RNA Splicing

1987 • 1,134 citations

The Fine Structure of the Nervous System

1991 • 1,058 citations

Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion.

1984 • 739 citations

Laminin promotes neuritic regeneration from cultured peripheral and central neurons.

1983 • 726 citations

Extracellular Matrix Molecules and their Receptors: Functions in Neural Development

1991 • 726 citations

Neurite extension by peripheral and central nervous system neurons in response to substratum-bound fibronectin and laminin

1983 • 672 citations

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

1988 • 653 citations

Kinetics of homophilic binding by embryonic and adult forms of the neural cell adhesion molecule.

1983 • 635 citations

Tenascin: An Extracellular Matrix Protein Prominent in Specialized Embryonic Tissues and Tumors

1989 • 604 citations

fine structure of the nervous system

1976 • 594 citations

Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere.

1990 • 588 citations

A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction

1989 • 566 citations

Peripheral Nerve Regeneration

1990 • 560 citations

Inhibitors of Neurite Growth

1993 • 545 citations

Nerve growth factor, laminin, and fibronectin promote neurite growth in human fetal sensory ganglia cultures

1982 • 541 citations

Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin

1985 • 538 citations

Extracellular Matrix Molecules that Influence Neural Development

1989 • 537 citations

Schwann cell basal lamina and nerve regeneration

1983 • 511 citations

Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons

1992 • 493 citations

Spatial‐Temporal progress of peripheral nerve regeneration within a silicone chamber: Parameters for a bioassay

1983 • 488 citations

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve.

1986 • 482 citations

Morphoregulatory molecules

1988 • 460 citations

PROTEIN COMPOSITION OF MYELIN OF THE PERIPHERAL NERVOUS SYSTEM

1973 • 446 citations

Structure of sulfated glucuronyl glycolipids in the nervous system reacting with HNK-1 antibody and some IgM paraproteins in neuropathy.

1986 • 432 citations

Identification of the major proteins that promote neuronal process outgrowth on Schwann cells in vitro.

1988 • 420 citations

Two contrary functions of tenascin: Dissection of the active sites by recombinant tenascin fragments

1989 • 415 citations

Neural cell adhesion molecules influence second messenger systems

1989 • 387 citations

Cell adhesion molecules in vertebrate neural development.

1988 • 386 citations

The L2/HNK-1 carbohydrate of neural cell adhesion molecules is involved in cell interactions.

1988 • 373 citations

The amino acid sequences of the myelin-associated glycoproteins: homology to the immunoglobulin gene superfamily

1987 • 370 citations

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and myelin-associated glycoprotein) in regenerating adult mouse sciatic nerve.

1988 • 364 citations

Motor axons preferentially reinnervate motor pathways

1993 • 362 citations

Adult and embryonic mouse neural cell adhesion molecules have different binding properties

1983 • 350 citations

Membrane glycoproteins involved in neurite fasciculation.

1987 • 347 citations

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.

1990 • 346 citations

Role of myelin Po protein as a homophilic adhesion molecule

1990 • 344 citations

Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction.

1987 • 335 citations

Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing.

1987 • 320 citations

Polysialic acid as a regulator of intramuscular nerve branching during embryonic development

1990 • 319 citations

Altered expression of neuronal cell adhesion molecules induced by nerve injury and repair.

1986 • 319 citations

Characterization of sulfated glucuronic acid containing glycolipids reacting with IgM M-proteins in patients with neuropathy.

1987 • 315 citations

Regenerative changes in rat dorsal roots following wallerian degeneration

1963 • 309 citations

Degeneration & regeneration of the nervous system

1928 • 306 citations

Preferential reinnervation of motor nerves by regenerating motor axons.

1988 • 301 citations

Enhanced expression of the developmentally regulated extracellular matrix molecule tenascin following adult brain injury.

1992 • 297 citations

Preferential reinnervation of motor nerves by regenerating motor axons

1988 • 291 citations

Studies of adhesion molecules mediating interactions between cells of peripheral nervous system indicate a major role for L1 in mediating sensory neuron growth on Schwann cells in culture.

1988 • 288 citations

Isolation from chick somites of a glycoprotein fraction that causes collapse of dorsal root ganglion growth cones

1990 • 286 citations

Molecular cloning and primary structure of myelin-associated glycoprotein.

1987 • 284 citations

Linkage Between Axonal Ensheathment and Basal Lamina Production by Schwann Cells

1986 • 284 citations

Three markers of adult non-myelin-forming Schwann cells, 217c(Ran-1), A5E3 and GFAP: development and regulation by neuron–Schwann cell interactions

1990 • 277 citations

J1/tenascin in substrate-bound and soluble form displays contrary effects on neurite outgrowth.

1991 • 276 citations

Protein zero of peripheral nerve myelin: Biosynthesis, membrane insertion, and evidence for homotypic interaction

1990 • 276 citations

The dermal-epidermal junction of human skin contains a novel laminin variant.

1992 • 268 citations

Expression of tenascin in the developing and adult cerebellar cortex

1992 • 267 citations

Development of the major pathways for neurite outgrowth in the chick hindlimb

1985 • 265 citations

Neurite outgrowth patterns in cerebellar microexplant cultures are affected by antibodies to the cell surface glycoprotein L1

1986 • 264 citations

Schwann cell precursors and their development

1991 • 261 citations

Potential of Schwann cells from unmyelinated nerves to produce myelin: a quantitative ultrastructural and radiographic study

1976 • 260 citations

Peanut agglutinin and chondroitin-6-sulfate are molecular markers for tissues that act as barriers to axon advance in the avian embryo

1991 • 260 citations

Unwrapping the genes of myelin

1988 • 246 citations

Immunohistological localization of the adhesion molecules L1, N‐CAM, and MAG in the developing and adult optic nerve of mice

1989 • 233 citations

Isolation and nucleotide sequence of mouse NCAM cDNA that codes for a Mr 79,000 polypeptide without a membrane-spanning region.

1987 • 231 citations

The relationships between interphase Schwann cells and axons before myelination: A quantitative electron microscopic study

1973 • 230 citations

Polysialic acid influences specific pathfinding by avian motoneurons

1992 • 229 citations

Neural cell recognition molecule F11: Homology with fibronectin type III and immunoglobulin type C domains

1989 • 222 citations

THE RELATIONSHIP BETWEEN AXONS AND SCHWANN CELLS DURING DEVELOPMENT OF PERIPHERAL NERVES IN THE RAT

1959 • 222 citations

Distinct roles for adhesion molecules during innervation of embryonic chick muscle

1988 • 219 citations

What distinguishes tenascin from fibronectin?

1990 • 219 citations

Molecular topography of the neural cell adhesion molecule N-CAM: surface orientation and location of sialic acid-rich and binding regions.

1983 • 217 citations

Tenascin promotes cerebellar granule cell migration and neurite outgrowth by different domains in the fibronectin type III repeats.

1992 • 211 citations

Structure of a glycolipid reacting with monoclonal IgM in neuropathy and with HNK-1

1985 • 211 citations

A detailed structural model of cytotactin: protein homologies, alternative RNA splicing, and binding regions.

1989 • 198 citations

Primary sequence of a motor neuron-selective adhesive site in the synaptic basal lamina protein s-laminin

1989 • 194 citations

Recombinant myelin-associated glycoprotein confers neural adhesion and neurite outgrowth function

1989 • 190 citations

Amino acid sequence of mouse tenascin and differential expression of two tenascin isoforms during embryogenesis.

1991 • 186 citations

The L2/HNK‐1 Carbohydrate Epitope is Involved in the Preferential Outgrowth of Motor Neurons on Ventral Roots and Motor Nerves

1992 • 183 citations

Expression of the neural cell adhesion molecules L1 and N-CAM and their common carbohydrate epitope L2/HNK-1 during development and after transection of the mouse sciatic nerve

1985 • 183 citations

Localization during development of alternatively spliced forms of cytotactin mRNA by in situ hybridization.

1990 • 179 citations

Carbohydrates and Carbohydrate-Binding Proteins in the Nervous System

1990 • 179 citations

Tenascin is accumulated along developing peripheral nerves and allows neurite outgrowth in vitro

1990 • 177 citations

Myelin-Associated Glycoprotein in Development and Disease

1983 • 172 citations

Inhibition of Schwann cell myelination in vitro by antibody to the L1 adhesion molecule

1990 • 169 citations

Enhanced expression of the extracellular matrix molecule J1/tenascin in the regenerating adult mouse sciatic nerve

1990 • 162 citations

Heterotypic binding between neuronal membrane vesicles and glial cells is mediated by a specific cell adhesion molecule.

1984 • 162 citations

An alternatively spliced region of the human hexabrachion contains a repeat of potential N-glycosylation sites.

1989 • 161 citations

T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo

1991 • 158 citations

The regulation of intramuscular nerve branching during normal development and following activity blockade

1988 • 158 citations

Sulfated glucuronic acid-containing glycoconjugates are temporally and spatially regulated antigens in the developing mammalian nervous system

1987 • 154 citations

Molecular structure and functional testing of human L1CAM: An interspecies comparison

1991 • 154 citations

The appearance of an L1-like molecule in the chick primary visual pathway

1986 • 152 citations

Retrovirally introduced antisense integrin RNA inhibits neuroblast migration in vivo

1992 • 151 citations

Role of macrophages in peripheral nerve degeneration and repair

1992 • 150 citations

Movements of the Schwann cell nucleus implicate progression of the inner (axon-related) Schwann cell process during myelination.

1989 • 145 citations

Recombinant peripheral myelin protein P_o confers both adhesion and neurite outgrowth‐promoting properties

1990 • 133 citations

Demonstration of immunochemical identity between the nerve growth factor-inducible large external (NILE) glycoprotein and the cell adhesion molecule L1.

1985 • 131 citations

Distribution of the adhesion molecules N-CAM and L1 on peripheral neurons and glia in adult rats

1986 • 127 citations

Alternatively spliced mRNAs code for different polypeptide chains of the chicken neural cell adhesion molecule (N-CAM).

1986 • 122 citations

Neuronal cell adhesion molecules and cytotactin are colocalized at the node of Ranvier.

1986 • 121 citations

Polysialic acid is required for optimal growth of axons on a neuronal substrate

1992 • 121 citations

Studies on the control of myelinogenesis. I. Myelination of regenerating axons after entry into a foreign unmyelinated nerve

1975 • 120 citations

Schwann cells: early lineage, regulation of proliferation and control of myelin formation

1992 • 119 citations

Polypeptide components and binding functions of neuron-glia cell adhesion molecules.

1984 • 118 citations

Expression of cytotactin in the normal and regenerating neuromuscular system.

1989 • 117 citations

Understanding the molecules of neural cell contacts: emerging patterns of structure and function

1989 • 114 citations

An LRE (leucine-arginine-glutamate)-dependent mechanism for adhesion of neurons to S-laminin

1991 • 111 citations

Identification of a cDNA clone that contains the complete coding sequence for a 140-kD rat NCAM polypeptide.

1987 • 110 citations

The role of Schwann cells in the development of human peripheral nerves

1965 • 110 citations

Molecular cloning of cDNA encoding the rat neural cell adhesion molecule L1 Two L1 isoforms in the cytoplasmic region are produced by differential splicing

1991 • 110 citations

Mitotic Schwann cells in developing nerve: Their changes in shape, fine structure, and axon relationships

1973 • 110 citations

Degenerative and regenerative changes in the trochlear nerve of goldfish

1984 • 108 citations

Isolation of mouse N-CAM-related cDNA: detection and cloning using monoclonal antibodies.

1985 • 108 citations

Cell Type‐specific Effects of the Neural Adhesion Molecules L1 and N‐CAM on Diverse Second Messenger Systems

1992 • 106 citations

Two developmentally regulated messenger RNAs differing in their coding region may exist for the myelin-associated glycoprotein.

1984 • 105 citations

Immunocytochemical localization of the myelin-associated glycoprotein Fact or Artifact?

1984 • 105 citations

Antibodies to the L1 adhesion molecule inhibit Schwann cell ensheathment of neurons in vitro.

1989 • 103 citations

Evidence for an early role for myelin‐associated glycoprotein in the process of myelination

1989 • 103 citations

Polysialic acid on the surface of axons regulates patterns of normal and activity-dependent innervation

1991 • 102 citations

Identification of a peripheral nerve neurite growth-promoting activity by development and use of an in vitro bioassay.

1987 • 101 citations

Immunohistological Localization of Tenascin in the Developing and Lesioned Adult Mouse Optic Nerve

1992 • 100 citations

P0 is an early marker of the schwann cell lineage in chickens

1991 • 99 citations

Schwann cells infected with a recombinant retrovirus expressing myelin-associated glycoprotein antisense RNA do not form myelin

1991 • 98 citations

Murine tenascin: cDNA cloning, structure and temporal expression of isoforms

1991 • 98 citations

Preferential motor reinnervation: a sequential double-labeling study

1990 • 92 citations

The perinotochordal mesenchyme acts as a barrier to axon advance in the chick embryo: Implications for a general mechanism of axonal guidance

1990 • 92 citations

NCAM: the molecule and its genetics

1986 • 92 citations

Immunoelectron microscopic localization of laminin in normal and regenerating mouse sciatic nerve

1990 • 90 citations

Immunocytological localization of the major peripheral nervous system glycoprotein P0 and the L2/HNK-1 and L3 carbohydrate structures in developing and adult mouse sciatic nerve

1988 • 87 citations

Characterization of a newt tenascin cDNA and localization of tenascin mRNA during newt limb regeneration by in situ hybridization

1991 • 87 citations

REGENERATION IN THE PERIPHERAL NERVOUS SYSTEM

1989 • 87 citations

Tenascin/J1/Cytotactin: The Potential Function of Hexabrachion Proteins in Neural Development

1989 • 86 citations

The monoclonal antibody HNK-1 reacts with a human peripheral nerve ganglioside

1984 • 86 citations

Myelinated, but not unmyelinated axons, reversibly down-regulate N-CAM in Schwann cells

1987 • 85 citations

The role of laminin, a component of Schwann cell basal lamina, in rat sciatic nerve regeneration within antiserum-treated nerve grafts

1992 • 81 citations

Binding properties of liposomes containing the myelin‐associated glycoprotein MAG to neural cell cultures

1990 • 80 citations

Molecular specificity of L2 monoclonal antibodies that bind to carbohydrate determinants of neural cell adhesion molecules and their resemblance to other monoclonal antibodies recognizing the myelin-associated glycoprotein

1986 • 80 citations

Purification and partial characterization of the myelin-associated glycoprotein from adult rat brain

1983 • 79 citations

Topographic maps and molecular gradients

1993 • 79 citations

Expression of recombinant myelin-associated glycoprotein in primary Schwann cells promotes the initial investment of axons by myelinating Schwann cells.

1990 • 75 citations

Expression of myelin protein gene transcripts by schwann cells of regenerating nerve

1990 • 65 citations

An in Vitro Neurite-Promoting Antigen Functions in Axonal Regeneration in Vivo

1987 • 64 citations

Growth of axons into developing muscles of the chick forelimb is preceded by cells that stain with Schwann cell antibodies

1987 • 64 citations

Neural Protein 1B236/Myelin‐Associated Glycoprotein (MAG) Defines a Subgroup of the Immunoglobulin Superfamily

1987 • 61 citations

Analysis of high PSA N-CAM expression during mammalian spinal cord and peripheral nervous system development

1991 • 57 citations

A neurite outgrowth-promoting molecule in developing fiber tracts

1988 • 55 citations

Physiological and morphological changes in developing peripheral nerves of rat embryos

1988 • 52 citations

Cells and cell‐interactions that guide motor axons in the developing chick embryo

1991 • 51 citations

Nerve-dependent and -independent tenascin expression in the developing chick limb bud

1991 • 51 citations

Complex expression pattern of tenascin during innervation of the posterior limb buds of the developing chicken

1991 • 50 citations

Molecular biology of the major myelin genes

1986 • 50 citations

A new membrane antigen revealed by monoclonal antibodies is associated with motoneuron axonal pathways

1989 • 44 citations

Molecular cloning of NILE glycoprotein and evidence for its continued expression in mature rat CNS

1991 • 41 citations

Accurate reinnervation of motor end plates after disruption of sheath cells and muscle fibers

1986 • 41 citations

Expression of the large myelin-associated glycoprotein isoform during the development in the mouse peripheral nervous system

1991 • 40 citations

The location and distribution of neural crest-derived Schwann cells in developing peripheral nerves in the chick forelimb

1992 • 39 citations

Myelin-Associated Glycoprotein Gene Expression in the Presence and Absence of Schwann Cell-Axonal Contact

1990 • 39 citations

Schwann cells depleted of galactocerebroside express myelin‐associated glycoprotein and initiate but do not continue the process of myelination

1990 • 35 citations

Migration of schwann cells and axons into developing chick forelimb muscles following removal of either the neural tube or the neural crest

1988 • 33 citations

Developmental Expression of the Myelin‐Associated Glycoprotein in the Peripheral Nervous System Is Different from That in the Central Nervous System

1985 • 32 citations

P₂, P₁, and P₀ myelin protein expression in developing rat sixth nerve: A quantitative immunocytochemical study

1987 • 29 citations

Endopeptidase-24.11 is suppressed in myelin-forming but not in non-myelin-forming schwann cells during development of the rat sciatic nerve

1992 • 27 citations

Intracellular associations of adhesion molecules

1993 • 27 citations

Changes in expression of mRNA specific for cell adhesion molecules (L1 and NCAM) in the transected peripheral nerve of the adult rat

1990 • 25 citations

A Schwann cell antigen recognized by monoclonal antibody 217c is the rat low-affinity nerve growth factor receptor

1991 • 20 citations

Laminin — developmental expression and role in axonal outgrowth in the peripheral nervous system of the chick

1992 • 19 citations

The expression of myelin-associated glycoprotein in regenerating cat sciatic nerve

1988 • 17 citations

Antibodies to the neural cell adhesion molecule disrupt functional recovery in injured nerves

1990 • 11 citations