Molecular characteristics of excitatory amino acid receptors

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1991 • 2,406 citations

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

The physiology of excitatory amino acids in the vertebrate central nervous system

1987 • 1,718 citations

Ca2 ⁺ Permeability of KA-AMPA—Gated Glutamate Receptor Channels Depends on Subunit Composition

1991 • 1,458 citations

A Family of AMPA-Selective Glutamate Receptors

1990 • 1,453 citations

Excitatory amino acid receptors in the vertebrate central nervous system.

1989 • 1,316 citations

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1990 • 1,234 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

NMDA receptors - their role in long-term potentiation

1987 • 1,177 citations

Cloning by functional expression of a member of the glutamate receptor family

1989 • 1,009 citations

Molecular Cloning and Functional Expression of Glutamate Receptor Subunit Genes

1990 • 925 citations

Structure-activity relationships in the development of excitatory ammo acid receptor agonists and competitive antagonists

1990 • 905 citations

Excitatory amino acid receptors and synaptic plasticity

1990 • 872 citations

Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels

1991 • 827 citations

Identification of a Site in Glutamate Receptor Subunits That Controls Calcium Permeability

1991 • 774 citations

Cooperative Modulation of [³H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

1988 • 755 citations

cDNA eloping of bovine substance-K receptor through oocyte expression system

1987 • 748 citations

A new type of glutamate receptor linked to inositol phospholipid metabolism

1987 • 743 citations

Glutamate stimulates inositol phosphate formation in striatal neurones

1985 • 734 citations

Agonists and antagonists for excitatory amino acid receptors

1987 • 692 citations

Glutamate activates multiple single channel conductances in hippocampal neurons

1987 • 691 citations

Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

1990 • 649 citations

Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development

1990 • 646 citations

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

1991 • 638 citations

A family of glutamate receptor genes: Evidence for the formation of heteromultimeric receptors with distinct channel properties

1990 • 581 citations

Cloning, Expression, and Gene Structure of a G Protein-Coupled Glutamate Receptor from Rat Brain

1991 • 524 citations

7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex.

1988 • 517 citations

Enhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal Neurons

1991 • 486 citations

Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells

1991 • 461 citations

Coupling of Inositol Phospholipid Metabolism with Excitatory Amino Acid Recognition Sites in Rat Hippocampus

1986 • 444 citations

Regulation of neurotransmitter receptor desensitization by protein phosphorylation

1990 • 439 citations

Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons

1987 • 420 citations

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

1991 • 404 citations

Excitatory amino acid receptors in the brain: membrane binding and receptor autoradiographic approaches

1990 • 397 citations

Ligand-gated ion channels in the brain: The amino acid receptor superfamily

1990 • 397 citations

Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate- and kainate-sensitive glutamate binding sites.

1985 • 374 citations

The structure of ion channels in membranes of excitable cells

1989 • 368 citations

Noncompetitive excitatory amino acid receptor antagonists

1990 • 361 citations

Protein phosphorylation in the nervous system

1984 • 329 citations

New class of glutamate agonist structurally related to ibotenic acid

1980 • 309 citations

A new mechanism for glutamate receptor action: phosphoinositide hydrolysis

1988 • 241 citations

Concanavalin A selectively reduces desensitization of mammalian neuronal quisqualate receptors.

1989 • 228 citations

Selective release of endogenous zinc from the hippocampal mossy fibers in situ

1987 • 220 citations

Complex structure of quisqualate-sensitive glutamate receptors in rat cortex

1985 • 216 citations

Permeation of Calcium Ions Through Non-NMDA Glutamate Channels in Retinal Bipolar Cells

1991 • 209 citations

Molecular structure of the chick cerebellar kainate-binding subunit of a putative glutamate receptor

1989 • 204 citations

Mechanisms of blockade of excitatory amino acid receptor channels

1990 • 199 citations

Modulation of Glutamate Receptors: Molecular Mechanisms and Functional Implications

1989 • 198 citations

Regulation of synaptic transmission in the central nervous system: Long-term potentiation

1989 • 186 citations

Sequence and expression of a frog brain complementary DNA encoding a kainate-binding protein

1989 • 181 citations

Functional expression from cloned cDNAs of glutamate receptor species responsive to kainate and quisqualate

1990 • 178 citations

The inhibitory glycine receptor: A ligand‐gated chloride channel of the central nervous system

1990 • 165 citations

Long‐lasting modification of the synaptic properties of rat CA3 hippocampal neurones induced by kainic acid.

1988 • 162 citations

Cloning of cDNA for the glutamate-binding subunit of an NMDA receptor complex

1991 • 160 citations

Activity-dependent plasticity in the visual systems of frogs and fish

1991 • 153 citations

Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.

1988 • 146 citations

Characterization of subtypes of excitatory amino acid receptors involved in the stimulation of inositol phosphate synthesis in rat brain synaptoneurosomes

1987 • 129 citations

Subcellular localization of a putative kainate receptor in Bergmann glial cells using a monoclonal antibody in the chick and fish cerebellar cortex

1990 • 115 citations

The non-NMDA receptors: types, protein structure and molecular biology

1990 • 115 citations

A Pertussis Toxin-Sensitive G Protein in Hippocampal Long-Term Potentiation

1989 • 114 citations

A comparison of excitatory amino acid antagonists acting at primary afferent C fibres and motoneurones of the isolated spinal cord of the rat

1987 • 109 citations

Calcium discriminates two [3H]kainate binding sites with different molecular target sizes in rat cortex

1986 • 95 citations

N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.

1989 • 90 citations

A kainic acid receptor from frog brain purified using domoic acid affinity chromatography.

1988 • 88 citations

Quinolinate differentiates between forebrain and cerebellar NMDA receptors

1991 • 81 citations

Differential stimulation of [3H]MK-801 binding to subpopulations of NMDA receptors

1991 • 79 citations

Phylogenetic distribution of [3H]kainic acid receptor binding sites in neuronal tissue

1980 • 72 citations

Solubilization of Kainic Acid Binding Sites from Rat Brain

1987 • 71 citations

Identification of a novel NMDA receptor in rat cerebellum

1991 • 70 citations

Immune labeling and purification of a 71-kDa glutamate-binding protein from brain synaptic membranes. Possible relationship of this protein to physiologic glutamate receptors.

1988 • 67 citations

Blockade of desensitization augments quisqualate excitotoxicity in hippocampal neurons

1990 • 65 citations

Cross‐desensitization Reveals Pharmacological Specificity of Excitatory Amino Acid Receptors in Isolated Hippocampal Neurons

1990 • 56 citations

Molecular target size analyses of the NMDA-receptor complex in rat cortex

1989 • 51 citations

Solubilization, partial purification, and reconstitution of glutamate- and N-methyl-D-aspartate-activated cation channels from brain synaptic membranes

1991 • 46 citations

N-Methyl-D-aspartate/phencyclidine receptor complex of rat forebrain: purification and biochemical characterization

1990 • 41 citations

Characterization and regional distribution of glutamatergic and cholinergic ligand binding sites in goldfish brain

1988 • 41 citations

Immunochemical characterization of brain synaptic membrane glutamate-binding proteins.

1990 • 39 citations

Evidence for a single glutamate receptor of the ionotropic kainate/quisqualate type.

1989 • 35 citations

Solubilization and partial purification of 3-((+-)-2-carboxypiperazine-4-yl)-[1,2-3H]propyl-1-phosphonic acid recognition proteins from rat brain synaptic membranes.

1990 • 34 citations

New wave of non-NMDA excitatory amino acid receptors

1991 • 29 citations

The interaction of a kainate receptor from goldfish brain with a pertussis toxin-sensitive GTP-binding protein

1991 • 27 citations

Spermine reciprocally changes the affinity of NMDA receptor agonists and antagonists

1991 • 23 citations

Distribution of a putative kainic acid receptor in the frog central nervous system determined with monoclonal and polyclonal antibodies: evidence for synaptic and extrasynaptic localization

1990 • 22 citations

Kainate Receptors in Xenopus Central Nervous System: Solubilisation with n‐Octyl‐β‐<scp>d</scp>‐Glucopyranoside

1989 • 21 citations

Autoradiographic distribution of binding sites for the non-NMDA receptor antagonist CNQX in chick brain

1990 • 20 citations

Immune labeling and purification of a 71-kDa glutamate-binding protein from brain synaptic membranes

1988 • 20 citations

Solubilization of Spermidine‐Sensitive (+)‐[³H]5‐Methyl‐10,11 ‐Dihydro‐5H‐Dibenzo[a,d]cyclohepten‐5,10‐Imine ([³H]MK‐801) Binding Activity from Rat Brain

1990 • 16 citations

Regional heterogeneity of rat brain phencyclidine (PCP) receptors revealed by photoaffinity labeling with [3H] azido phencyclidine

1985 • 12 citations

Excitatory amino acid receptors in piriform cortex do not show receptor desensitization

1988 • 9 citations

Vintage amino acid meeting describes new tools for amino acid research, subtypes of metabotropic receptors

1991 • 6 citations