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Targeting MYC dependence in cancer by inhibiting BET bromodomains

Data up to Jan 2025

Published2011
Citations1,054
References22

Total Citations Per Year

Abstract

References (22)

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

2005 • 44,461 citations

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

2003 • 8,996 citations

Selective inhibition of BET bromodomains

2010 • 3,775 citations

Suppression of inflammation by a synthetic histone mimic

2010 • 1,459 citations

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

2008 • 1,002 citations

Myc’s broad reach

2008 • 887 citations

Oncogene Addiction

2008 • 744 citations

Elongation by RNA polymerase II: the short and long of it

2004 • 701 citations

Myc suppression of the p21Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

2002 • 676 citations

IRF4 addiction in multiple myeloma

2008 • 668 citations

The Double Bromodomain-containing Chromatin Adaptor Brd4 and Transcriptional Regulation

2007 • 625 citations

The Myc oncoprotein as a therapeutic target for human cancer

2006 • 533 citations

Translocations involving c-myc and c-myc function

2001 • 465 citations

The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription

2008 • 361 citations

Brd4 Recruits P-TEFb to Chromosomes at Late Mitosis To Promote G1 Gene Expression and Cell Cycle Progression

2007 • 340 citations

Negative Regulation of the Mammalian UV Response by Myc through Association with Miz-1

2002 • 306 citations

Brd4 Marks Select Genes on Mitotic Chromatin and Directs Postmitotic Transcription

2009 • 302 citations

MYC in Oncogenesis and as a Target for Cancer Therapies

2010 • 246 citations

MYC regulation of a “poor-prognosis” metastatic cancer cell state

2010 • 175 citations

NUT midline carcinoma

2010 • 174 citations

Characterization of MYC Translocations in Multiple Myeloma Cell Lines

2008 • 120 citations

A Novel Raji-Burkitt's Lymphoma Model for Preclinical and Mechanistic Evaluation of CD52-Targeted Immunotherapeutic Agents

2008 • 28 citations

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Targeting MYC dependence in cancer by inhibiting BET bromodomains (2011) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer