The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Transcriptional regulation by the phosphorylation-dependent factor CREB

2001 • 2,488 citations

CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals

1999 • 2,076 citations

Mediation by a CREB Family Transcription Factor of NGF-Dependent Survival of Sympathetic Neurons

1999 • 794 citations

Myc-driven murine prostate cancer shares molecular features with human prostate tumors

2003 • 787 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 729 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 637 citations

Myc-Induced T Cell Leukemia in Transgenic Zebrafish

2003 • 543 citations

G<scp>ENETICS OF</scp> M<scp>YELOID</scp> L<scp>EUKEMIAS</scp>

2002 • 530 citations

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

2001 • 426 citations

Flow cytometric identification of murine neutrophils and monocytes

1996 • 357 citations

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

2003 • 297 citations

TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION

1999 • 293 citations

Enforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op Mice

1997 • 292 citations

Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor

1993 • 283 citations

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

2004 • 264 citations

Cell Cycle Regulation of Cyclin A Gene Expression by the Cyclic AMP-Responsive Transcription Factors CREB and CREM

1995 • 233 citations

Cyclin-Dependent Kinases and S Phase Control in Mammalian Cells

2003 • 226 citations

Dimerization of MLL fusion proteins immortalizes hematopoietic cells

2003 • 174 citations

Molecular genetics of acute myeloid leukaemia

2001 • 164 citations

G1 control in mammalian cells

1994 • 154 citations

Mouse MRP8 and MRP14, two intracellular calcium-binding proteins associated with the development of the myeloid lineage

1992 • 141 citations

Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter.

1994 • 96 citations

Cyclin A1 expression in leukemia and normal hematopoietic cells.

1999 • 86 citations

p38 MAP kinase activation mediates γ-globin gene induction in erythroid progenitors

2003 • 80 citations

Altered myelopoiesis and the development of acute myeloid leukemia in transgenic mice overexpressing cyclin A1

2001 • 78 citations

Induction of Apoptosis in BCR/ABL+ Cells By Histone Deacetylase Inhibitors Involves Reciprocal Effects on the RAF/MEK/ERK and JNK Pathways

2003 • 70 citations

Transcriptional Activation of egr-1 by Granulocyte-Macrophage Colony-stimulating Factor but Not Interleukin 3 Requires Phosphorylation of cAMP Response Element-binding Protein (CREB) on Serine 133

1995 • 68 citations

Expression of cyclic adenosine monophosphate response-element binding protein in acute leukemia

2002 • 67 citations

Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function

2001 • 58 citations

Expression of Calcium-Binding Proteins MRP8 and MRP14 Is Associated with Distinct Monocytic Differentiation Pathways in HL-60 Cells

1993 • 56 citations

Transcription factors and translocations in lymphoid and myeloid leukemia

2001 • 54 citations

Prostacylin Receptor Activation Inhibits Proliferation of Aortic Smooth Muscle Cells by Regulating cAMP Response Element-Binding Protein- and Pocket Protein-Dependent Cyclin A Gene Expression

2003 • 51 citations

Reciprocal products of chromosomal translocations in human cancer pathogenesis: key players or innocent bystanders?

2002 • 46 citations

Acute myelogenous leukemia

2002 • 45 citations

Granulocyte Colony-stimulating Factor Induces egr-1Up-regulation through Interaction of Serum Response Element-binding Proteins

2000 • 40 citations

Granulocyte-macrophage colony-stimulating factor stimulation results in phosphorylation of cAMP response element-binding protein through activation of pp90RSK

2000 • 40 citations

Assignment of the human gene for CREB1 to chromosome 2q32.3–q34

1990 • 30 citations

Granulocyte-Macrophage Colony-stimulating Factor Induces the Transcriptional Activation of egr-1 through a Protein Kinase A-independent Signaling Pathway

1995 • 30 citations

Progress in the treatment of acute myeloid leukaemia in adults

2002 • 16 citations

Physical localization of chromosome 20 markers using somatic cell hybrid cell lines and fluorescence in Situ hybridization

1992 • 16 citations

Elevated levels of cyclin A1 and A (A2) mRNA in acute myeloid leukaemia are associated with increased survival

2003 • 15 citations

p55Cdc/Cdc20 Overexpression Promotes Early G ₁ /S Transition in Myeloid Cells

2001 • 11 citations

Analysis of cell death in myeloid cells inducibly expressing the cell cycle protein p55Cdc.

1998 • 10 citations

Changes in Phenotypically Distinct Phagocyte Subpopulations during Nonspecific Modulation of Contact Sensitization

1993 • 4 citations